The invention discloses a method for building an
animal model of social position induced depression, which belongs to the technical field of life sciences. The method comprises the following steps of: in natural colonies of non-human primates, recording total
curling time, total spontaneous
activity time and total external stimuli reaction time of each individual; dividing the total
curling time of each individual into four equal parts, wherein the individuals with the shortest
curling time are abnormal and others are depressive; performing independent sample t experiments on the hourly average spontaneous
activity time and the hourly average external stimuli reaction time of the individuals of the two groups, wherein if the spontaneous
activity time and the reaction time of the individuals of the
normal group are obviously longer than those of the individuals of the depressive group, the individuals of the depressive group meet behavior characteristic requirements; and measuring hair
cortisone content and partial
cerebral blood flow values of the individuals of the two groups to perform the independent sample t detection, wherein if the average
cortisone content of the individuals of the
normal group is obviously lower than that of the depressive group and the average partial
cerebral blood flow value of the individuals of the
normal group is obviously higher than that of the depressive group, the individuals of the depressive group meet biochemical criterion requirements. The individuals who simultaneously meet the two types of requirements are the built natural depressive models, so the method can completely simulate the evolution of human depression.