90 results about "Independent samples" patented technology

An instrument is disclosed for fluorescence assays which is capable of reading many independent samples at the same time. This instrument provides enhanced throughput relative to single-sample instruments, and is well-suited to use in general fluorescence, time-resolved fluorescence, multi-band fluorescence, fluorescence resonance energy transfer (FRET), and fluorescence polarization. This invention is beneficial in applications such as high-throughput drug screening, and automated clinical testing. Also disclosed are means and methods for a fluorescence polarization measurement which is highly sensitive, inherently self-calibrated, and unaffected by lamp flicker or photobleaching. This fluorescence polarization invention can be practiced on a variety of fluorescence instruments, including prior-art equipment such as microscopes and multi-well plate readers.

An instrument is disclosed for fluorescence assays which is capable of reading many independent samples at the same time. This instrument provides enhanced throughput relative to single-sample instruments, and is well-suited to use in general fluorescence, time-resolved fluorescence, multi-band fluorescence, fluorescence resonance energy transfer (FRET), and fluorescence polarization. This invention is beneficial in applications such as high-throughput drug screening, and automated clinical testing. Also disclosed are means and methods for a fluorescence polarization measurement which is highly sensitive, inherently self-calibrated, and unaffected by lamp flicker or photobleaching. This fluorescence polarization invention can be practiced on a variety of fluorescence instruments, including prior-art equipment such as microscopes and multi-well plate readers.

A signal-to-noise estimator is provided for estimating the signal-to-noise ratio in wireless fading channels. The estimator can be applied to likelihood ratio estimation of turbo decoders in third generation wide-band code division multiple access (WCDMA) systems. Time-multiplexed samples of pilot symbols from a wireless receiver are supplied to the estimator to obtain individual estimates of signal power and / or noise power. The estimator uses a de-correlating filter in which the coefficients are known functions (such as eigen-vectors) of the auto-correlation matrix for a wireless channel. The decorrelating filter is used by the estimator to map an observation vector into a set of statistically independent samples. The energy of each vector component is computed individually and combined to produce an aggregate sum for the vector. The aggregate sum can be subtracted from the pilot tone power in order to produce an estimate of noise power.

The invention provides a seabed pore water collection device, comprising: a sampling column, which is composed of a plurality of sampling bottles connected end to end, each sampling bottle is provided with two sealed and independent sample storage chambers, and one end of each sample storage chamber There is a channel connected to the outside of the sampling bottle and controlled by a solenoid valve, and a filter layer is provided at the opening end of the channel; the control barrel is installed at one end of the sampling column, including a sealed operating room, and a control sampling bottle installed in the operating room The working control unit, and the power storage unit that provides power for the control unit; the control unit controls the two solenoid valves of each sampling bottle to open at intervals for a certain period of time according to predetermined conditions when sampling, so as to realize sequential sampling. The invention collects samples successively through two sample storage rooms, so that the samples in the second sample storage room can avoid being polluted by seawater, improve the resolution of pore water samples, and provide technical support for the fine detection of natural gas hydrate geochemical characteristics .

The invention discloses an efficient screw-in soil sampling device. The efficient rotary soil sampling device comprises a bracket and a sampling barrel, wherein a moving rod is arranged in the sampling barrel; the left side of the moving rod is fixedly connected with a pulling tray; the tail end of the right side of the moving rod is fixedly connected with a moving block; the moving block is pressed against a fixed block; the left side of the fixed block is fixedly connected with a sampling pipe; a sliding plate is arranged below the sampling pipe; a sample box is arranged below the sliding plate; the sample box is provided with a plurality of independent sample grids. A screw-in driving device is provided, so that a sampling depth can be reached accurately, and the sampling accuracy is increased; the sampling barrel is provided to obtain soil samples at different depths by one-time perforation, and the sampling efficiency is increased; the rotary sample box which is provided with the independent sample grids is provided for separating and storing soil samples, so that mutual pollution among the soil samples is avoided, the samples are prevented from falling off at the same time, the sample quantity is ensured, and sampling demands are satisfied.

The invention discloses a dry-type biochemical test strip for simultaneously detecting trinomial blood lipid. The dry-type biochemical test strip successively comprises the following parts from top to bottom: an upper baffle, an interlayer and a bottom support. The upper baffle is provided with three independent sample introduction holes. The interlayer is provided with a blood diffusion layer, a filter layer, a hydrophilic layer and a reagent layer which are successively arranged from top to bottom. The bottom support is equipped with three small holes corresponding to the upper baffle. The test strip has advantages of unique design and ingenious conception. By the adoption of the test strip, detection efficiency can be raised, dosage of samples and detection reagents is minimized, detection time is shortened, cost is reduced, and pains of patients are decreased. The test strip is applicable to be popularized in the family at large scale.

The invention relates to a multi-sample stage allowing for automatic movement of inverted microscopes. The multi-sample stage comprises a sample stage base and an objective lens. Screw supports are arranged on the sample stage base. A screw is arranged on the two screw supports through a coupling. The coupling is connected with a drive motor. A slide is arranged on the sample stage base. A sample cell moving rack is arranged on the slide. The top of the sample cell moving rack is screwed to the screw through a connector. A sample cell fixed rack is arranged on the sample stage base and is provided with a sample cell. The upper surface of the sample cell is made of a quartz glass slide, and the lower surface of the sample cell is made of a cover glass. The periphery of each of the quartz glass slide and the cover glass is sealed with epoxy resin. Space between the quartz slide glass and the cover glass is divided into a plurality of independent sample channels. The quartz glass slide is provided with through holes corresponding to the independent sample channels. The through holes are connected with an automatic sample feeder through sample guide tubes. The multi-sample stage is applicable to various inverted microscopes, is small in size, handy, flexible, and simple and fast to operate, and is an effective tool for the biological single-molecular study.

The invention provides a biochemical micro-reaction system which comprises a first oily liquid, a second oily liquid, a water-based gene sample and a reaction reagent, wherein the density of the first oily liquid is greater than that of the second oily liquid; the water-based gene sample and the reaction reagent are embedded between the first oily liquid and the second oily liquid to form a sandwich structure; the water-based gene sample and the reaction reagent are immiscible and do not react with the first oily liquid and the second oily liquid; and the first oily liquid and the second oily liquid are immiscible. In the biochemical micro-reaction system, each independent sample in a biochemical reaction process can be completely controlled and separated to avoid cross contamination, and a large quantity of consumables can be saved. The invention also provides a high-throughput sequencing database builder based on the biochemical micro-reaction system and an application.

The invention discloses a sampling method for establishing a tobacco near-infrared model, comprising the following steps of: obtaining near-infrared scanning spectrograms of tobacco samples in two mutually independent sample sets (A) and (B); carrying out spectrum preprocessing on the near-infrared scanning spectrograms; obtaining the spectrum Mahalanobis distance di from a sample i to the sample set (A); obtaining the component value distance di' from the sample i to the sample set (A); obtaining the integral Euclidean distance Di from the sample i in the sample set (B) to the sample set (A); selecting samples in the sample set (B) according to specific principles and then adding to the sample set (A) to form a new sample set (A'), and finally obtaining a new near-infrared model A' by the establishment of the sample set (A'). The invention overcomes the problem that the prior art can not give attention to predictive ability and model authenticity and provides a sampling method being capable of getting rid of invalid exceptional data; the established model has good predictive ability and applicability and can be widely applied to tobacco industry.

The invention discloses a rice lodging monitoring method using a thermal infrared image. The method is as follows: 1, farmland image acquisition, to be more specific, fixed point acquisition by an unmanned aerial vehicle (UAV) carrying thermal infrared imaging equipment; 2, characteristic value extraction, to be more specific, extraction of a color characteristic value, a texture characteristic value and a temperature characteristic value of a target area by image analysis tool Matlab; 3, construction of a lodging region discrimination model, to be more specific, training of the rice lodging discrimination model by the characteristic values extracted by the step 2 and known lodging conditions; 4, calibration of the lodging discrimination model, to be more specific, collecting of more lodging rice and non lodging rice samples for calibration of the lodging discrimination model trained in the step 3; and 5, verifying of the lodging discrimination model, to be more specific, verifying ofthe lodging discrimination model calibrated by the step 4 by an independent sample. The method uses the thermal infrared image to identify the difference between a lodging area and a non lodging areaof rice, and provides an effective means for lodging monitoring of the rice.

The invention discloses a successive approximation type analog-to-digital conversion device. The successive approximation type analog-to-digital conversion device comprises a sample-and-hold circuit, a comparator, a shift register, a digital-to-analog converter, a clock generation circuit and a reference voltage generation circuit. The minimum sampling error can be obtained by adopting the independent sample-and-hold circuit, and a most significant bit charge scaling digital-to-analog converter body, a least significant bit voltage scaling digital-to-analog converter body, an amplifier and the like of the digital-to-analog converter form a closed-loop switched capacitor amplifier. Due to the structure, the influence of charge injection and clock feed-through can be eliminated, the load capacitance of the amplifier can be reduced, and accordingly the power consumption can be reduced. In addition, a gapping switch is additionally arranged between the charge scaling digital-to-analog converter body and the amplifier for isolation, and therefore additional charging current caused by charge averaging can be eliminated.

The invention discloses a swept source based common-channel optical coherence tomography (OCT) system and method. The system comprises a broadband swept source, a three-terminal circulator, a probe, an interference system and a control processing system. The probe comprises a GRIN lens and an MEMS (micro-electromechanical system) mirror. Laser emitted by the broadband swept source enters the probe via the three-terminal circulator, part of the laser is converged via the GRIN lens in the probe, the laser after being reflected from the probe via the MEMS mirror is irradiated onto a sample to perform one-dimensional or two-dimensional scanning on the sample so as to obtain sample information, and the converged laser with the sample information returns to the three-end circulator to form reference light. Sample light and the reference light enter the interference system via the three-terminal circulator to form an interference signal, and the interference signal enters the control processing system to be processed to form a sample image. By the OCT system and method, the reference light is provided directly through the end face of the GRIN lens replacing an independent sample arm, and the structure is simple.

The invention discloses a nucleic acid label for second-generation high-flux sequencing and a design method thereof, and relates to a nucleic acid label. The invention provides the nucleic acid label for second-generation high-flux sequencing and the a design method thereof, which are capable of quickly, efficiently, specially and simultaneously labeling almost one hundred independent samples, applicable to the mixed sequencing of a plurality of samples and used under the condition with a 96-pore plate. The nucleic acid label comprises an A group including eight labels with the length of 5nt,a B group including eight labels with the length of 5nt and a C group including twelve labels with the length of 6nt. Designing a first tag sequence: Tag 1: CTAGA; designing other three tags: Tag 2: TGCAG; Tag 3: ACGTC; Tag 4: GATCT; designing other four tags: Tag 5: CGTAC; Tag 6: TAGCA; Tag 7: ATCGT; Tag 8: GCATG; and calculating a positional number with an identical basic group between every two tags.

The present invention relates to methods and systems for the analysis of the dissociation behavior of nucleic acids and the identification of nucleic acids. In one aspect, methods and systems are disclosed for identifying a nucleic acid in a sample including an unknown nucleic acid and for detecting a single nucleotide polymorphism in a nucleic acid in a sample. In another aspect, methods and systems are disclosed for identification of a nucleic acid in a biological sample including at least one unknown nucleic acid by fitting denaturation data including measurements of a quantifiable physical change of the sample at a plurality of independent sample property points to a function to determine an intrinsic physical value and to obtain an estimated physical change function, and identifying the nucleic acid in the biological sample by comparing the intrinsic physical value for at least one unknown nucleic acid to an intrinsic physical value for a known nucleic acid.

Disclosed is a system using each of the descrete emitters in a III-nitride micro-emitter array as a light source for measuring the properties of independent samples of biological materials deposed on a micro-array using some form of detecting device, e.g, a detector array or charge-coupled device. In embodiments the emitter array produces deep ultraviolet in investigating protein-protein interactions or to detect biological and chemical molecules with high specificity by monitoring changes in a protein's intrinsic fluorescence.

Systems and methods that facilitate dimensional transformations of data points are disclosed. In particular, the subject invention provides for a system and methodology that simplifies dimensional transformations while mitigating variations of a distance property between pairs of points. A set of n data points in d dimensional space is represented as an n×d input matrix, where d also corresponds to the number of attributes per data point. A transformed matrix represents the n data points in a lower dimensionality k after being mapped. The transformed matrix is an n×k matrix, where k is the number of attributes per data point and is less than d. The transformed matrix is obtained by multiplying the input matrix by a suitable projection matrix. The projection matrix is generated by randomly populating the entries of the matrix with binary or ternary values according to a probability distribution. Unlike previous methods, the projection matrix is formed without obtaining an independent sample from a Gaussian distribution for each entry in the projection matrix, without applying a linear algebraic technique to generate the projection matrix and without employing arbitrary floating point numbers. Processes and / or algorithms can utilize the reduced transformed matrix instead of the larger input matrix to facilitate computational efficiency and data compression.

The invention relates to an infringement detection method for software codes. The infringement detection method specifically comprises a detection server and a local detection agent; transformed software code key feature information instead of the original form of a software code is transmitted between the detection server and the local detection agent and is stored on a server side; a cloud side detection server is in charge of managing a code feature sample library used for infringement detection and carrying out detection on the basis of an infringement rule; and the local detection agent is in charge of extracting and generating the software code key feature information, reporting the information to a cloud server and carries out localized reading on infringement information issued by the cloud server. Since the method transmits the transformed information between the cloud detection server and the local agent, a software owner does not need to provide a source code, and infringement detection can be carried out astride an organizational boundary. The cloud server positioned in the center can span the organizational boundary, each software development organization does not need to maintain one set of independent sample library, and the cost of the software development organization is lowered. By use of the method, the infringement detection capability of a whole Internet level can be achieved.

The invention discloses a method for building an animal model of social position induced depression, which belongs to the technical field of life sciences. The method comprises the following steps of: in natural colonies of non-human primates, recording total curling time, total spontaneous activity time and total external stimuli reaction time of each individual; dividing the total curling time of each individual into four equal parts, wherein the individuals with the shortest curling time are abnormal and others are depressive; performing independent sample t experiments on the hourly average spontaneous activity time and the hourly average external stimuli reaction time of the individuals of the two groups, wherein if the spontaneous activity time and the reaction time of the individuals of the normal group are obviously longer than those of the individuals of the depressive group, the individuals of the depressive group meet behavior characteristic requirements; and measuring hair cortisone content and partial cerebral blood flow values of the individuals of the two groups to perform the independent sample t detection, wherein if the average cortisone content of the individuals of the normal group is obviously lower than that of the depressive group and the average partial cerebral blood flow value of the individuals of the normal group is obviously higher than that of the depressive group, the individuals of the depressive group meet biochemical criterion requirements. The individuals who simultaneously meet the two types of requirements are the built natural depressive models, so the method can completely simulate the evolution of human depression.

A photoionization detector comprising multiple ionization cells for detecting the presence of chemical compounds in multiple fluid samples. The photoionization detector uses a single source of ultraviolet (UV) radiation to emit high energy photons into at least two ionization cells. Each ionization cell comprises at least one fluid inlet and at least one fluid outlet. Independent samples of fluid can be introduced into each cell and exposed to the UV radiation such that any molecules with an ionization energy lower that the energy of the photons are ionized. Each ionization cell also comprises a set of at least two electrodes arranged to generate an electric field such that ionized molecules are attracted to the electrode at lower voltage potential resulting in an electrical current.

The invention discloses a method for rapidly detecting the nutrient composition of barley straw. The method comprises the following steps: (1) chemical analysis of the nutrient composition of barley straw; (2) near infrared spectrum data collection for a barley straw sample; (3) original spectrum preprocessing; (4) building standard sample screening; (5) calibration model establishment; (6) determination of an optimal model; and (7) model external verification. MPLS is used for improving least square method regression technology matched and combined with different spectrum processing methods and parameters, and establishment for a barley straw near infrared external model is established; three indexes such as 1-VR, SECV and SEC are used for determining the optimal model; and an independent sample set without participating a model calibration process is adopted for carrying out external verification on the optimal model. An NIRS calibration model is established for the nutrient composition in the barley straw sample by using the NIRS technology, corresponding external verification is carried out on the model, the feasibility of the main composition of barley straw predicted by the model is determined, and a method for rapidly predicting the nutrient composition of barley straw is provided in the production process.

The invention discloses a built environment landscape characteristic recognition method based on an internet picture, wherein the recognition method comprises the steps as follows: using the Baidu picture search engine to obtain photographic picture libraries of a target environment and a similar built environment; recording a shooting standing point, a shooting vision central point and a shooting sight line of a shooting behavior in the target environment and importing the recorded information in an analysis platform of ArcGIS, and using ArcGIS software to analyze a visual sensitive region of the target environment in the internet picture and analyzing the sensitivity; by using the network photographic picture libraries of the target environment and the similar built environment, recording feature attributes of the network photographic pictures of the two network photographic picture libraries, and using the independent-sample T test to select a vision characteristic feature of the target environment. Thus, the landscape characteristic of a target built environment is recognized and analyzed. The built environment landscape characteristic recognition method based on the internet picture of the invention could be used for performing visual image analysis to the landscape of a city built environment, and have replicability and operability. The built environment landscape characteristic recognition method based on the internet picture of the invention could use photographer visual analysis of the internet picture and reduction analysis of the shooting behavior, and have timeliness and objectivity.

The invention relates to a method for t detection of an influence degree of an additive on special smoke indexes of a cigarette, belonging to the technical field of the tobacco. The method comprises the following steps of: determining test indexes as special smoke indexes of the cigarette, mainly comprising the contents of phenol, crotonaldehyde, hydrocyanic acid, ammonia and NNK ([4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone]) in main stream smoke; selecting the concentration of the additive; selecting reference test design for experimentation; processing test results, namely examining an independent sample t; and determining the influence degree of the additive on the special smoke indexes of the cigarette according to the examination result of the independent sample t. The method, in the application process, has the following advantages that: whether the influence of the additive on the special smoke indexes of the cigarette is obvious can be determined, and the determination and conclusion are scientific and reliable; and the method has great realistic significance on determining the efficacy of the harm-reducing and tar-decreasing additive and improving the quality safety of the cigarette product.

The invention provides a dustfall collection method for separating impurities. By adopting the method, impurities can be filtered in the course of natural subsidence and collection, thereby improving the purity degree of a collected sample, preventing the sample from directly being exposed in gas flow, effectively restraining 'secondary dusting', improving dry-type sampling efficiency and effectively decreasing the water evaporation inside a collector simultaneously so that a wet-type collection can be also carried out in drought area; the dustfall sample is directly collected in an independent sample storage unit so that the sample is more convenient to be collected and the work load is reduced; the method has wide applicable areas in both drought and humid regions and can be widely applied in research in aspects of environment, ecology, aeolian landform, sand control works and the like.

The present invention relates to methods and systems for the analysis of the dissociation behavior of nucleic acids and the identification of nucleic acids. In one aspect, methods and systems are disclosed for identifying a nucleic acid in a sample including an unknown nucleic acid and for detecting a single nucleotide polymorphism in a nucleic acid in a sample. In another aspect, methods and systems are disclosed for identification of a nucleic acid in a biological sample including at least one unknown nucleic acid by fitting denaturation data including measurements of a quantifiable physical change of the sample at a plurality of independent sample property points to a function to determine an intrinsic physical value and to obtain an estimated physical change function, and identifying the nucleic acid in the biological sample by comparing the intrinsic physical value for at least one unknown nucleic acid to an intrinsic physical value for a known nucleic acid.

The invention relates to a method for simultaneously analyzing at least two samples using a chromatography device comprising a chromatography column having an inlet and an outlet, and at least one detector placed at the outlet of the chromatography column, the method comprising steps of: injecting fractions of each independent sample at the inlet of the chromatography column, the fractions of each independent sample being injected according to a specific injection timing sequence derived from a pseudo-random binary sequence associated with said independent sample; recording a signal generated by said detector for a period of time at least equal to a duration of the longest of the specific injection timing sequences; cross-correlating the recorded signal and a derived correlation function, said derived correlation function being derived from the pseudo-random binary sequence associated with one of the independent samples, so as to obtain an individual correlogram signal specific to said independent sample; and analyzing data of interest of the individual correlogram signal so as to obtain an output signal indicative of a composition of the sample.

The invention discloses a microphone array fault detection method and a microphone array fault detection device.The microphone array fault detection method comprises steps that an independent samplingdata set of a signal acquisition channel of each microphone of a microphone array is acquired; whether speech signals exist in each independent sampling data set is detected. By adopting the microphone array fault detection method, whether the signal acquisition channel of each microphone of the microphone array is faulted can be detected.

The invention discloses a nondestructive testing method for the freezing storage period of pork based on an electronic nose. The nondestructive testing method comprises the following steps: step S01, sampling: extracting a frozen pork sample; step S02, data acquisition: carrying out headspace gas acquisition on the pork sample by using the electronic nose; step S03, establishment of a prediction model: observing the capability of the electronic nose in distinguishing different freezing storage periods and long-time refrigeration before freezing storage by using principal component analysis, variance analysis based on repeated measurement data and nonparametric testing of independent samples, and then establishing the prediction model for determining the freezing storage period of pork and for determining whether pork has undergone long-time refrigeration before freezing storage by using an artificial neural network algorithm; and step S04, result prediction: predicting results according the headspace gas acquisition results of the unknown sample and the prediction model. The nondestructive testing method provided by the invention is applicable to rapid and nondestructive testing of the freezing storage period of frozen pork and testing of whether frozen pork has undergone long-time refrigeration before freezing storage.

The invention discloses a non-targeting analysis method for organic pollutants in sediment based on a statistical strategy and belongs to the technical field of environmental analytical chemistry. Themethod comprises the following steps: a) carrying out analysis and detection on a target solution subjected to sediment treatment; b), dividing the sediment into two different groups; screening a characteristic response peak of significant difference between different groups of the sediment by utilizing a statistical analysis method; then carrying out structure identification. Firstly, a first-grade response peak is extracted and the response peak of the significant difference between the different groups is screened by utilizing non-parametric test of an independent sample; then a molecularformula of the response peak is calculated; a possible structural formula is searched through a database. Finally, fragment analog computation is carried out on the possible structural formula; when all fragments are matched with a second-grade mass spectrogram, the possible structural formula is used as a candidate structural formula. According to the method disclosed by the invention, substanceswith concentration difference between sediment samples of different ages or regions can be rapidly and effectively analyzed under the condition that a lot of unknown samples exist, and the method iseasy to popularize.

The invention provides a detection device which comprises a detection cavity body, wherein a detection cavity is formed inside the detection cavity body; a gas adjusting material is arranged between the detection cavity and an external exchanged atmosphere; when the gas adjusting material is dry, gas circulation between the detection cavity and the external atmosphere is implemented through the gas adjusting material; when the gas adjusting material is wet, gas circulation between the detection cavity and the external atmosphere is not implemented through the gas adjusting material. By adopting the structure, the detection device has the characteristics of being simple and reasonable in structure, low in use material cost and excellent in property; the gas adjusting material (such as a sponge core) has a function of preventing liquid leakage, meanwhile the air pressure inside a sample detection cavity can be effectively adjusted, a constant sample detection liquid surface can be maintained, a stable detection result can be ensured, and in addition due to adoption of an independent sample storage cavity (collection cavity), an excessive sample is not contaminated by reagents, and convenience can be brought to secondary detection.

The invention discloses a source stirring method of an electrical modulation electromagnetic wave orbit angular momentum mode for reducing reverberation room measurement uncertainty. An electrically modulated vortex electromagnetic metasurface is deployed in a reverberation room, thus, a brand new degree of freedom is introduced; for the electromagnetic wave orbit angular momentum, various independent electromagnetic wave orbit angular momentum modes can be controlled and switched through an electrical modulation mode, independent sample number is increased effectively, the source stirring method can be used simultaneously with other stirring methods under a limited space condition, measurement uncertainty is reduced further, when the source stirring method is used simultaneously with theother stirring methods, and under a condition where total sample number is fixed, overall test time can be controlled through control of the number of work modes of the electromagnetic metasurface. The method provided by the invention can effectively reduce measurement uncertainty of the reverberation room, and has the characteristics of occupying small space, using simple modulation modes, needing short test time, being convenient to make, and being low-cost.