35 results about "Stomach motility" patented technology

Motilide compounds having the formula (I), wherein R1, R2, R3, and R4 are as defined herein, and methods for their preparation and use in the treatment of diseases or conditions characterized by impaired gastric motility.

The invention discloses a composition for improving a dissolution rate of a benzamide gastric motility drug. The composition specifically comprises a benzamide gastric motility drug containing at least one amino and / or ammonium salts thereof as well as at least one organic acid. The composition disclosed by the invention generates a local acidic microenvironment after being dissolved, and therefore, the influence of a pH value of a medium on the dissolution rate of the active ingredients is slight, and non-pH dependence dissolution is realized. Therefore, a high dissolution rate also can be realized under the condition that pH value in a digestive tract greatly changes, so that the influence of differences in diet or constitution on the curative effect of the drug is reduced, the dissolution rate of active ingredients of the drug can be effectively improved, and the bioavailability is improved. The composition is low in production cost and easy to use and can realize non-pH dependence release of the active ingredients of the drug. Moreover, a prescription of the composition disclosed by the invention does not comprise a surfactant, and the composition is suitable for a patient sensitive to the surfactant.

The invention relates to new functions and applications of trametes lactinea(Berk.)Pat. or extractives and trametenloic acid B. The substance trametes lactinea(Berk.)Pat has the functions of digestive gastric ulcer resistance, and nonulcerative-indigestion resistance through increasing of gastric motility. The trametes lactinea(Berk.)Pat. or the extractives and the trametenloic acid B have certain inbibitional effects on cell proliferation of gastric cancer cells, esophagus cancer cells Eca-109 and colorectal cancer cells LOVO, and has a wide range of research value and mass production and edible value in dugs for digestive system and gastric cancer resisting and the like.

The invention discloses a veterinary compound pharmaceutical composition containing albendazole and ivermectin, and relates to the field of veterinary drug technical preparation. The veterinary compound pharmaceutical composition comprises the following components: albendazole, ivermectin, sulfamonomethoxine, lactobacillus and soluble starch. The veterinary antiparasitic pharmaceutical composition is convenient to use, is mutually synergistic, has broad spectrum of insect resistance and good insect-resistant effect, can increase gastric motility, increases feed intake, and is in favor of the growth of livestock. The pharmaceutical compound of the invention can be a dry suspension, can be directly added in an automatic drinking device in proportion, is convenient to use, and has wide application prospects.

The invention provides various devices for delivering Glucagon-Like Peptide-1 (7-36), in various infusion patterns and rates, to optimally stimulate carbohydrate metabolism, to inhibit gastropancreatic secretion and gastric motility, and to treat various disease conditions (including diabete) as described in the instant specification. The devices and methods of the invention provide various ways to deliver doses (escalating, constant, on demand, etc.) of GLP-1 in response to different patient need.

The invention relates to a preparation method of traditional Chinese medicine, in particular to a drug capable of increasing gastric motility and treating chronic gastritis and a preparation method thereof. The drug is prepared via mixing drug residues, licorice, poria cocos, fructus evodiae, grifola and rhizoma pinelliae preparata, adding water of five times, soaking for 60 minutes, extracting for 5 hours in heat reflux, filtering to prepare 1000 pieces and then coating icing. The losses of effective ingredients of the drug prepared by the preparation method are reduced. Compared with the traditional process, the yield is increased. Moreover, the drug can be rapidly absorbed in the human body. The effective ingredients are not decomposed during the preparation process, and thus the bioavailability of the drug is improved. Therefore, the preparation method has obvious advantages than the original method. Compared with the product prepared in the original process, the ratio of cream extraction is increased by 3 percent, and the bioavailability can be increased by 13 percent. Therefore, the effects are obvious after process innovation, and the efficacy of the product is improved greatly.

The invention discloses a multi-flavor glutinous rice cake having multiple nutrition functions, and a production method thereof, wherein mainly 800-1200 parts by weight of glutinous rice, and a stuffing comprising 20-40 parts by weight of white granulated sugar, 40-60 parts by weight of raisin, 40-60 parts by weight of peach preserved fruit, 40-60 parts by weight of wax gourd strips, 40-60 parts by weight of lotus seeds, 40-60 parts by weight of mung bean, 40-60 parts by weight of red beans, 40-60 parts by weight of apricot kernel and 40-60 parts by weight of chestnut kernel are stacked sequentially, and compacting, steaming, cooling, molding, and packaging are performed to obtain the product. According to the present invention, the single formula of the traditional glutinous rice cake is changed; and the mung beans, the red beans, the raisins and other raw materials being rich in a variety of vitamins, amino acids and trace elements are added as the auxiliary materials, such that the nutrients of the product are enriched, the taste of the product is improved, and the obtained product is fragrant and delicious compared with the traditional glutinous rice cake, has effects of intestine and stomach motility enhancing and digestion and absorption promoting, and further has characteristics of simple production method, rich taste, unique flavor, and no greasy feeling after more eating of the multi-flavor glutinous rice cake.

Methods and compositions for regulating fatty acid uptake and / or decreasing gastric motility in an animal are provided. The method comprises administering an antagonist of integrin αvβ3 or αvβ5 to an animal in an amount sufficient to reduce fatty acid uptake in the animal, thereby reducing fatty acid uptake in the animal. In some embodiments, the antagonist is an antibody. Also provided is a method of increasing fatty acid uptake and / or gastric motility in an animal.

The invention relates to a method for preparing the traditional Chinese medicine composition for preventing and treating gastropathy, which belongs to the technical field of the traditional Chinese medicine for preventing and treating gastropathy. The traditional Chinese medicine composition is composed of Sichuan fritillary bulb, notopterygium root, purslane speedwell, Chinese yam, coix seeds, white hyaciath bean, cinnamon, angelica, bitter orange, honeysuckle flower, evodia fruit, dahurian angelica root and aucklandia root. The preparation method comprises the following steps: firstly, all the medicines are divided into three groups; secondly, the first group of medicines is pulverized into course powder; thirdly, the second group of medicines is distilled; fourthly, the third group of medicines is ethanol-extracted; fifthly, the medicines and the gruffs are decocted; sixthly, the filtrate, the distillate and the ethanol filtrate are uniformly mixed and concentrated; seventhly, the crude medicine is prepared. The preparation method has the advantages that the gastric mucous membrane is quickly protected, the nidus is inhibited in time, and damaged cell factors of gastric mucous membrane can be quickly recovered; a variety of pathogens can be quickly killed, the alkalinity-acidity balance of the gastrointestinal tracts can be adjusted, the muscular cells can be conducive to being re-generated, the damaged cells of gastric mucous membrane can grow quickly, no toxic or side effect can be caused, the blood circulation can be improved, and the gastric motility can be enhanced; but the treatment effect is relatively slow.

The invention provides a micro-ecological preparation with a function of degrading ochratoxin and a preparation method thereof. The micro-ecological preparation is prepared from clostridium butyricum, bacillus natto, bacillus natto coagulans, a fomes officinalis extract, sodium butyrate, a liquid culture medium and the like. The micro-ecological preparation with a function of degrading ochratoxin is stable in property, can be used for decomposing pollution caused by ochratoxin in feed with high anti-pollution performance, and can be used for remarkably increasing the gastrointestinal motility, enhancing the gastric motility, relieving gastrointestinal discomfort or abdominal distension and regulating gastrointestinal flatulence.

The invention provides a medicament for treating gastric ulcer and a preparation method thereof. A formula of the medicament comprises components of, by weight, 50-250 parts of turmeric, 50-250 parts of purple ginger, 50-250 parts of epigeal srephaia root, 50-250 parts of grass-leaved sweetflag rhizome, 50-250 parts of brassica integrifolia seed, 50-250 parts of dragon ' s blood and 50-330 parts of honey. The medicament can be prepared into a honeyed pill by crushing the five medicinal materials of turmeric, purple ginger, epigeal srephaia root, grass-leaved sweetflag rhizome and brassica integrifolia seed, adding dragon ' s blood, mixing well, adding a proper amount of honey and water, carrying out fanwan, drying at a low temperature, and processing into a honeyed pill. Or the medicamentcan be prepared into other dosage forms. The medicament of the invention can enhance digesting function of patients, and kill abnormally fermented helicobacter pylori in stomach and intestine, and iscapable of relaxing stomach and intestine smooth muscle, alleviating spasm ache, increasing gastric motility, promoting stomach peristalsis and further normalizing stomach digesting function. The medicament has effects of improving stomach microcirculation, promoting blood-supply function of stomach, invigorating blood circulation, scattering stasis, astringing sores, engendering flesh, and protecting gastric mucosa, and can supply sugar and trace elements in time, enable a digestive system to adjust immediately to recover.

The invention relates to a simethicone compound recipe liquid composition and a preparation method and application thereof. The simethicone compound recipe liquid composition comprises simethicone andgastric motility promoting medicines or pharmaceutically-acceptable salts of the gastric motility promoting medicines, wherein the gastric motility promoting medicines are one or two of Itopride, mosapride and cisapride, and the mass ratio of the simethicone to the gastric motility promoting medicines or the pharmaceutically-acceptable salts of the gastric motility promoting medicines is (10-40)to 1. The simethicone and the gastric motility promoting medicines are compounded in a specific proportion and are made into the form of a liquid preparation, so that the defoaming capacity is strengthened, and defoaming can be completed only within 3-5 seconds; and besides, the stability is good, and the simethicone compound recipe liquid composition can still maintain better preparation shape and better defoaming capacity after being stored for 30 days.

The invention provides an intestine and stomach restoring and gastrointestinal mucosa protecting medicinal and edible composition. The intestine and stomach restoring and gastrointestinal mucosa protecting medicinal and edible composition is mainly prepared from raw materials including, by weight, 4.5-11 parts of American ginseng, 3-7 parts of medlar, 2.5-6 parts of jujubes, 5-10 parts of bletilla striata, 3.5-6 parts of hawthorn, 4.5-11 parts of immature bitter orange, 2-5.5 parts of malt, 1-5 parts of poria cocos, 2-6 parts of fructus amomi and 0.5-4 parts of fructus evodiae. The preparation method includes selecting and cleaning all the raw materials prior to irradiating, smashing, drying and mixed grinding into powder with the mesh sizes to be over 80 meshes to obtain a tablet or a capsule. The intestine and stomach restoring and gastrointestinal mucosa protecting medicinal and edible composition is simple in match, the raw materials are easy to get, and the apart from common functions of increasing stomach power, warming the stomach, diminishing inflammation, relieving pain and the like, the composition further has efficacies of restoring and regenerating of mucous membrane and restoring normal gastric mucosa and function thereof.

The invention discloses a traditional Chinese medicine composition for treating functional dyspepsia and a preparation method thereof. The composition is prepared from the following raw materials: radix bupleuri, pericarpium citri reticulatae and fructus aurantii; wherein the weight ratio of radix bupleuri to pericarpium citri reticulatae to fructus aurantii is (5-7): (5-7): (4-6); radix bupleuriis used as a liver-soothing medicine; pericarpium citri reticulatae and the fructus aurantii are used for regulating qi; the effects of soothing the liver, regulating qi and harmonizing the liver andthe spleen are achieved; weight is increased effectively, appetite is increased, the mental state is improved (sucrose preference percentage is increased), the autonomous activity is increased, gastric residue is reduced, the content of motilin and the like is increased, the content of p substance, the expression of 5-HT and 5-HT4R can be further up-regulated, Ca<2+> internal flow of is increased,and the regulation effect of a 5-HT system on gastrointestinal tracts is enhanced, thereby promoting gastric motility improvement; therefore, the functional dyspepsia is treated from the root and symptoms, both symptoms and root causes are treated, and the traditional Chinese medicine composition has universality for various dialectical types of the functional dyspepsia.

The invention discloses chicken silage capable of improving meat quality and a preparation technology thereof. The chicken silage capable of improving meat quality comprises the following raw materials in parts by weight: 55-65 parts of Russian comfrey, 50-60 parts of ryegrass, 40-50 parts of lotus japonicus, 30-40 parts of oat germ powder, 16-20 parts of glucomannan-coated calcite, 2-3 parts of asilage fermentation agent, and 0.8-1.2 parts of feed additives; and the feed additives comprise moringa seed oil, nuciferine, L-carnitine tartrate, mint powder, allicin, saccharicter-penin, beta-carotene, plant active selenium, selenate polysaccharides and chloride choline. The preparation technology of the chicken silage capable of improving meat quality comprises the following steps: S1, preparing a semi-dry premix; S2, tightly pressing the semi-dry premix until the volume of the semi-dry premix is reduced by 55-65%, and carrying out wrapped fermentation, wherein extrusion is performed during the fermentation process once every 3 days; S3, preparing glucomannan-coated calcite; and S4, carrying out uniform blending and granulation. The chicken silage produced by the preparation technology is capable of effectively preventing excessive fatty acid accumulation in chicken meat, as well as endowing the chicken meat with natural grass aroma, so as to improve quality and flavor of the chicken meat; moreover, the chicken silage is also capable of promoting gastrointestinal peristalsis of chicken, as well as improving gastric motility.

The invention discloses a preparation process of preserved eggs, which comprises the following steps: step 1, preparing materials; step 2, stirring the materials; and step 3, preparing coating materials. According to the preserved egg prepared by the invention, the coating material can be uniformly distributed on the surface of the preserved egg, and by arranging a reflux unit, the coating material keeps fluidity and the binding power is greatly improved, so that the surface of the preserved egg can be firmly coated with the soft coating material, and the high-grade preserved egg is prepared.The preserved egg is free of any additive, is fully ecological, is beneficial to human health, is crystal clear in color and luster, is fragrant, smooth and tender in mouth, is long in aftertaste, isfree of lead and nitrite, and has special effects of strengthening physique, helping digestion and improving gastric motility, and the fragrance of eggs is long-lasting and lingers on the lips and teeth.

The invention discloses a Chinese herbal granule for treating diabetes gastroparesis, and relates to a Chinese herbal preparation. The Chinese herbal granule for treating the diabetes gastroparesis is characterized by being prepared by, by mass, the following traditional Chinese medicine raw materials of 7.2-8.8% of radix trichosanthis, 6-7.4% of rhizoma phragmitis, 5.4-6.6% of moutan bark, 3.6-4.4% of wahlenbergia marginata, 5.4-6.6% of malt sugar, 6-7.4% of paederia scandens, 7.2-8.8% of rice sprouts, 5.4-6.6% of agilawood, 5.9-7.3% of rhizoma cyperi, 7.2-8.8% of pericarpium citri reticulatae viride, 7.2-8.8% of lotus petiole, 7.2-8.8% of verbena officinalis, 5.4-6.6% of rhizoma curcumae longae, 5.4-6.6% of rhizoma curcumae and 5.4-6.6% of semen lablab album. The Chinese herbal granule has the effects of discharging liver and regulating qi, promoting circulation and removing stasis, clearing heat and promoting fluid, promoting digestion and tonifying spleen, reducing blood sugar and quenching thirsty, strengthening gastric motility and promoting gastrointestinal motility and is convenient to take, good in symptomatic property, rapid to display effects and good in treatment effect, and the cure rate is 90.32 percent.

The invention relates to the field of traditional Chinese medicine for animal disease treatment, in particular to traditional Chinese medicine for treating dog and cat intestinal obstruction and a preparation method thereof. The traditional Chinese medicine for treating dog and cat intestinal obstruction is prepared from the following raw materials in parts by weight: 8 to 15 parts of radix aconiti sinensis, 10 to 20 parts of cassia twigs, 10 to 20 parts of cortex magnoliae officinalis, 15 to 25 parts of radix et rhizoma rhei, 10 to 20 parts of peach kernels, 5 to 10 parts of sodium sulfate, 10 to 20 parts of radix paeoniae alba, 5 to 10 parts of radix glycyrrhizae preparata, 10 to 20 parts of rhizoma zingiber officinale, 8 to 15 parts of fructus ziziphi jujubae and 15 to 25 parts of honey. The traditional Chinese medicine is put into an extraction tank; water is added; decoction boiling and backflow extraction are performed twice; the decoction solutions in the two times are merged; then, filtering is performed; the filter liquid is concentrated and is then cooled to the room temperature to obtain traditional Chinese medicine liquid. The traditional Chinese medicine has the effects of enhancing gastrointestinal motility, stopping pain, eliminating fullness expansion, relieving abdominal pain, warming middle, nourishing the stomach and enhancing the stomach motility through thescientific matching according to the monarch, minister, assistant and guide principle.

The invention provides a feed additive for promoting growth of cattle and sheep and a preparation method thereof. The feed additive is prepared from the following raw materials in parts by weight: 50-60 parts of traditional Chinese medicine composition, 1-5 parts of probiotics, 5-10 parts of enzyme preparation and 10-15 parts of coated vitamin, wherein the traditional Chinese medicine compositioncomprises 10-20 parts of astragalus membranaceus, 5-10 parts of codonopsis pilosula, 15-20 parts of herba epimedii, 10-15 parts of medicated leaven, 5-10 parts of malt, 5-10 parts of hawthorn, 1-5 parts of mangnolia officinalis, 4-8 parts of ash bark, 5-10 parts of pericarpium citri reticulatae viride and 1-5 parts of rhizoma atractylodis. The feed additive provided by the invention is capable ofenhancing gastric motility, promoting rumination, enhancing digestion, increasing feed conversion rate, boosting immunity, reducing epidemic diseases, resisting virus, resisting bacteria and stoppingdysentery.

The invention discloses a feed additive for improving gastric motility. The additive comprises vitamin C, citric acid, probiotics, compound enzyme, hawthorn, malt, fast acid, mangnolia officinalis and cortex fraxini. The feed additive capable of improving the gastric motility has the effects of promoting appetite and appetite, relieving forestomach retardation, promoting rumination and enhancing the gastric motility, and the feed intake is obviously increased before slaughtering.

The invention discloses a device for treating gastroplegia. The device comprises a vibration mechanism and a flow guide mechanism, the vibration mechanism is detachably connected to the flow guide mechanism through a connecting piece, the vibration mechanism comprises a shell and a vibrator, the vibrator is installed in the shell, and the vibration mechanism is used for driving surrounding substances to vibrate; and one end of the flow guide mechanism is closed, a cover body is arranged at the other end of the flow guide mechanism, a wire with one end located outside the flow guide mechanism and the other end penetrating through the connecting piece to be connected to the vibrator is arranged in the flow guide mechanism, and scales are arranged on the outer wall of the flow guide mechanism. The device can effectively promote recovery of gastric motility under non-invasive conditions.

The present invention provides an extract of betel nut for improving gastric motility and its preparation process and application. The preparation process includes the following steps: take fried betel nut Chinese medicinal material and crush it, and use ether, ethanol, and chloroform in a volume ratio of 1:0.2-0.3:0.03- 0.05 as the extraction solvent, then add carbonate buffer, shake for 20-40 minutes, heat and reflux for 20-40 minutes, collect the extract, repeat the reflux extraction for 2-3 times, combine the total extract, add composite adsorption agent, the composite adsorbent is made of chitosan, diatomaceous earth, and activated carbon, and left to stand for 15-20min; filtered, and the filtrate is concentrated under reduced pressure at 60-70°C to form a thick paste, dried, and obtained. The betel nut extract obtained by the present invention not only significantly improves the transfer rate of arecoline, arecoline, and areca nut polyphenols, but also effectively removes heavy metals such as lead, arsenic, and mercury, improves the activity and safety of the areca nut extract, and can significantly reduce phenols in the stomach of mice. Red residual rate, has a good gastric emptying effect, can be better used in the preparation of drugs to improve gastric motility.

Disclosed herein is a method of treatment of gastric motility disorders and of improving gastric motility comprising treatment with the NK-1 receptor antagonist, tradipitant.

The invention provides a gastric motility promoting pharmaceutical composition. The pharmaceutical composition consists of coking malt, hawthorn, semen cannabis, rhizoma cyperi, szechwan chinaberry fruit, aloe, ruta graveolens, dried tangerine peel, herba schizonepetae, ricinus communis, fructus aurantii immaturus, Chinese yam, basil leaves, red dates and cabbage. The pharmaceutical composition can promote the gastric motility, promotes contraction performance of gastric smooth muscles, makes contraction frequency accelerated, the amplitude enlarged and the tension increased, and has a remarkable curative effect on gastric motility disorder diseases. Moreover, the pharmaceutical composition has no drug administration toxicity, has quite high security, and has quite good popularization and application prospects.

The cooked small fish is prepared from the following raw materials in parts by weight: 50-100 parts of fresh small fish, 5-10 parts of seasoning, 10-15 parts of vegetable oil, 1-3 parts of prebiotics, 1-3 parts of fermented soybeans and 2-5 parts of nutritional materials. The added prebiotics are beneficial to intestinal health and are raw materials for growth and reproduction of intestinal probiotics, the added fermented soybeans contain a large amount of probiotics and components beneficial to intestinal tracts, after being eaten, the fermented soybeans can promote intestinal peristalsis, protect gastric mucosa, improve gastric motility and benefit human health, and the fermented soybeans and the nutritional materials have the effects of promoting intestinal tract movement, protecting gastric mucosa and improving gastric motility. The effects of reducing blood fat and resisting oxidation are also achieved.

The invention discloses a gastric motility promoting medicine as well as a preparation method and application thereof. The method comprises the following steps that hawthorn, medicated leaven and roasted malt are added into water according to a mass ratio, decocting is conducted to obtain a decoction, filtering is conducted to obtain a filtrate, and the filtrate is concentrated to obtain a water extraction extract; the alcohol content of the extract is made to be 50 %-80 % through ethyl alcohol, stirring, standing and filtering are conducted, ethyl alcohol is recycled, and alcohol liquid is concentrated to obtain an alcohol extraction thick paste; and auxiliary materials are added into the thick paste, and uniformly mixing and drying are conducted to prepare a preparation to obtain a gastric motility promoting pharmaceutical preparation. According to the method, on the basis of the prescription of an existing big hawthorn pill, a technology is subjected to secondary development, innovation and promotion, the weight of retained effective components is reduced, the daily dosage of the medicine is reduced, the preparation of various preparations is facilitated, the compliance of patients is improved, and the quality of the variety can be integrally improved; and as a novel gastric motility promoting medicine, the medicine has high clinical value and provides medicine guarantee forrelated patients with gastropathy.

The invention provides a microecological preparation for decomposing ochratoxin and a preparation method thereof. The microecological preparation includes Clostridium butyricum, Bacillus natto, Bacillus coagulans, extract of FOMESOFFICINALIS, sodium butyrate, liquid culture medium and the like. The micro-ecological preparation that can decompose ochratoxin provided by the invention has stable properties, can decompose the pollution caused by ochratoxin in feed, has strong anti-pollution ability, can significantly increase gastrointestinal motility, enhance gastric motility, and relieve gastrointestinal discomfort or bloating, to regulate flatulence.

The invention relates to a stomach power medicine for curing function failure of stomach intestine and its preparing method, prepared of the following raw materials in weight proportion: fried radix bupleuri 5-20, radix paeoniae alba 5-20, Asarum sieboldii 3-8, fuling 10-25, fried Radix scutellariae 10-25, Rhizoma Pinellinae Praeparata 5-20, areca-nut 10-20, raw rheum officinale 5-15, the membrane of a chicken's gizzard 5-20 and fruit of citron or trifoliate orange 5-20. It is used mainly to cure abdominal distension, bellyache, constipation, etc, and achieves better clinic effect in wide application to internal medicine, surgical department and department of orthopedics. It gives full play to the curative advantages of multiple uses and multiple target points of compound traditional Chinese medicine, convenient to take, low-price, having no obvious toxicity and side effect, and it is a pure Chinese medicinal preparation with a good prospect in applying and developing.