26results about "Lactose production" patented technology

The present invention relates to methods to produce crystalline lactose, more specifically lactose obtained from a biotechnological production process.

A simple method for animal-free lactose synthesis. The present invention relates to a method for producing lactose, more particularly without separation from mammalian milk. Further, the present invention provides a method for purifying the lactose produced.

The disclosure provides methods and apparatuses for removing a yellow color of riboflavin in a lactose solution. The methods include exposing a lactose solution (e.g. milk) containing riboflavin to light under conditions that breakdown riboflavin comprised within the solution to thereby remove the yellow color of riboflavin. The conditions that breakdown include a specific wavelength of light (e.g. light having a wavelength of 360-475 nm) and a specific temperature range (e.g. a temperature of 0-80° C.). In certain embodiments, the duration of the treatment is such that the lactose solution is exposed to a total of 5-20 kW of light.

The present invention relates to a method of removing calcium citrate from a liquid dairy stream. In particular, the present invention relates to a method of removing calcium citrate from a liquid dairy stream wherein the liquid dairy stream has a pH below 6.2 or is optionally adjusted to be below 6.2, and wherein said liquid dairy stream having a pH below 6.2 is subjected to a step of precipitation of calcium citrate. Subsequently, the precipitated calcium citrate can be separated.

The present invention relates to a method for removing calcium citrate from a liquid dairy stream. Specifically, the present invention relates to a process for removing calcium citrate from a liquid dairy product stream wherein the liquid dairy product stream has a pH of less than 6.2 or is optionally adjusted to a pH of less than 6.2, and wherein the liquid dairy product stream having a pH of less than 6.2 is subjected to a calcium citrate precipitation step. Subsequently, the precipitated calcium citrate may be separated.

The invention pertains to an infant formula powder composition comprising micronized lactose or lactose microcrystals (i) smaller than 30 micrometer, and / or (ii) of which at least 80 % has a size less than 20 micrometer, and / or (iii) at least 80 % has a size less than 10 micrometer, and / or (iv) having a median particle size D50 below 10 micrometer. The invention also pertains to the use of micronized lactose or lactose microcrystals for improving flow of an infant formula powder composition.

The invention provides an anti-solvent fluid mechanics control device and method for flower-shaped porous lactose recrystallization equipment, and the device comprises a reaction kettle, a first stirrer, a second stirrer, a flow guide member, a nozzle unit, a multi-zone sensor and a dynamic controller, the flow guide member divides the interior of the reaction kettle into a low-shear growth zone and a high-shear mixing zone; the nozzle unit comprises at least one first nozzle, a second nozzle and a third nozzle; the multi-zone sensor comprises a PVM probe, an FBRM probe and a turbidimeter; when the reaction kettle runs, injecting a lactose saturated solution into the low-shear growth area, starting the first nozzle to add an anti-solvent in a dispersion mode, starting a pulse mode of the second nozzle when the PVM probe detects that the petal profile ratio reaches a preset value, and increasing the flow of the third nozzle when the FBRM probe detects that the growth rate is lower than the preset value. According to the invention, the problem of unstable form of flower type lactose crystal is solved mainly through fluid mechanics partitioning, multi-nozzle cooperation and dynamic control.

The drying and conveying production line for lactose preparation comprises a stirring and extruding module, a vibrating screen module and a roller drying and feeding module, and the stirring and extruding module, the vibrating screen module and the roller drying and feeding module are matched with one another to jointly form the production line; the stirring and extruding module comprises a material containing hopper component and a material extruding component, the material containing hopper component and the material extruding component are stacked up and down and communicate with each other, the material containing hopper component can receive and stir materials to be processed, and the stirred materials can flow into the material extruding component from top to bottom; the material extrusion component can extrude materials to be processed; the vibrating screen module comprises a screening box and a distributing component, and the screening box can receive the to-be-processed materials extruded by the material extrusion component and screen the to-be-processed materials through the distributing component according to the sizes of the to-be-processed materials. According to the technical scheme, the structure is reasonable, the materials can be stirred, mixed, formed, dried and conveyed in one step, and the purposes of stirring, mixing, forming, drying and conveying of the materials are achieved on the whole.

Disclosed is a method of inhibiting isomerization of a reducing saccharide in an aqueous solution containing said reducing saccharide upon thermal treatment of said aqueous saccharide solution by acidifying the aqueous saccharide solution prior to its thermal treatment, and the use of the thermally treated aqueous solution containing said reducing saccharide for producing a biological product.

The present invention relates to a supercritical carbon dioxide process equipment for preparing α / β mixed crystal porous lactose particles, comprising a supercritical fluid preparation unit, an atomization unit, a collection unit, a vibrating screen and a control unit; the supercritical fluid preparation unit is used for heating carbon dioxide to a supercritical temperature and pressurizing it to a supercritical pressure, and the supercritical fluid preparation unit includes a heater, a high-pressure pump, a pressure regulating valve and a flow meter; the atomization unit is used for mixing the heated carbon dioxide with a lactose solution and spraying it to form a mist, and the atomization unit includes a nozzle, a mixing chamber and a lactose solution heater; the collection unit is used for collecting and cooling the sprayed mist to generate α / β mixed crystal porous lactose particles, and the collection unit includes a collection cylinder and a cooling device; the vibrating screen is used for sorting the generated lactose particles, and the vibrating screen includes a screen body and a screen mesh; the control unit includes a temperature and pressure sensor and a controller. The technical solution of the present application can reliably prepare α / β mixed crystal porous lactose particles.

The present invention relates to a method of removing calcium citrate from a liquid dairy stream. In particular, the present invention relates to a method of removing calcium citrate from a liquid dairy stream wherein the liquid dairy stream has a pH below 6.2 or is optionally adjusted to be below 6.2, and wherein said liquid dairy stream having a pH below 6.2 is subjected to a step of precipitation of calcium citrate. Subsequently, the precipitated calcium citrate can be separated.

A sugar mixture comprising: monosaccharides; oligosaccharides in a ratio ≥0.06 to total saccharides; disaccharides in a ratio to total saccharides ≥0.05; pentose in a ratio to total saccharides ≥0.05; at least one alpha-bonded di-glucose; and at least one beta-bonded di-glucose. Also disclosed are methods to make and / or use such mixtures.

The present invention relates to a method of removing calcium citrate from a liquid dairy stream. In particular, the present invention relates to a method of removing calcium citrate from a liquid dairy stream wherein the liquid dairy stream has a pH below 6.2 or is optionally adjusted to be below 6.2, and wherein said liquid dairy stream having a pH below 6.2 is subjected to a step of precipitation of calcium citrate. Subsequently, the precipitated calcium citrate can be separated.

A crystallization apparatus for a crystallization of a preliminary product. The crystallization apparatus includes an inlet for receiving the preliminary product, a rotary drive, and a rotatable receiving unit having, on an upper side thereof, a circular surface and / or an annular surface for the crystallization so that, when the rotatable receiving unit is rotated, the preliminary product received can be recrystallized in a defined manner on the circular surface and / or the annular surface and can be discharged as a crystallized product.

To provide solid preparations of human milk oligo saccharides and methods for manufacturing of solid preparations of human milk oligosaccharides.SOLUTION: The present invention provides spray-dried powder consisting essentially of 3-fucosyllactose which has been produced by microbial fermentation, and a nutritional composition containing the spray-dried powder. A method for manufacture of the spray-dried powder comprises the steps of: a) purifying the 3-fucosyllactose from a fermentation broth; b) providing an aqueous solution containing the 3-fucosyllactose of the step a); and c) subjecting the solution of the step b) to spray-drying.SELECTED DRAWING: Figure 1

The present invention provides a process of producing a lactose concentrate, said process comprising the step of subjecting a partially demineralised aqueous lactose isolate to electrodialysis to produce a biotin-reduced lactose isolate containing at least 90% lactose by weight of dry matter and less than 2 mg ash per gram of lactose, and containing:0.02-1.5 mg sodium per gram of lactose;0.02-2 mg potassium per gram of lactose;0.05-1.5 mg chloride per gram of lactose;0.01-0.25 μg biotin per gram of lactose.The present invention also relates to a demineralised lactose concentrate having a reduced biotin content that can be produced by the aforementioned process. The invention further relates to an oligosaccharide-enriched biotin-reduced fraction that is obtained when lactose is separated before or after the electrodialysis step.

The present invention relates to a method for producing crystalline lactose, more particularly lactose obtained from a biotechnological production process.

The lactose production and purification device comprises a support, a stirring box is installed on one side in the support, a stirring motor is installed at the top of the stirring box, the bottom output end of the stirring motor penetrates into the stirring box to be connected with a stirring piece, and a liquid outlet is formed in the bottom of the stirring box. The device has the beneficial effects that through the design of the connecting mechanism and the filtering mechanism, when a nanofiltration membrane in a current filtering structure cannot be used, the other group of nanofiltration membranes can be automatically switched to be matched with a purification device for use, and the used nanofiltration membranes can be switched to a cleaning station; the nanofiltration membrane and the filter cavity are replaced and cleaned by a mechanical arm or a cleaning worker, so that the cleaning and replacement of the nanofiltration membrane and the use of the purification equipment do not influence each other and are relatively independent, and finally, the purification device can be used without shutdown and can meet the use requirements of an automatic production line.

The present invention relates to methods to produce crystalline lactose, more specifically lactose obtained from a biotechnological production process.

The present invention discloses a disaccharide crystallization and a preparation method thereof. The preparation method of the disaccharide crystallization comprises: filtering, microfiltrating and ultrafiltrating a disaccharide solution, and performing vacuum concentration to obtain a concentrated sugar solution; the disaccharide solution comprises a disaccharide raw material and water; mixing the concentrated sugar solution with ethanol, cooling, and adding a seed crystal and then keeping warm; the volume ratio of the ethanol to the concentrated sugar solution is (0.4-0.6):1; the seed crystal is a disaccharide crystal; cooling, and mixing with ethanol during the cooling process, and the volume ratio of the ethanol to the concentrated sugar solution is (0.4-0.6):1. The preparation method of the present invention improves the yield and purity of the disaccharide crystal, greatly shortens the crystallization time, and improves the production efficiency; the obtained disaccharide crystallization has the advantages of light color, high purity, few impurities and low bacterial endotoxin.

Methods for preparing spray dried lactose are provided. Methods include concentrating an aqueous lactose source, crystallizing at least a portion of the lactose in the concentrated lactose source, and forming a crystallized lactose slurry comprising a plurality of lactose particles. Methods include washing the crystallized lactose slurry for a period of time sufficient to reduce an absolute value of a b*-value color of the lactose particles by greater than or about 75%. Methods include wet milling the crystallized lactose slurry, reducing a D50 particle size of the plurality of lactose particles by greater than or about 50%. Methods include spray drying the crystallized lactose slurry, forming a plurality of spray dried lactose particles.

The present invention relates to methods to produce lactose, more specifically without the need for isolation from mammalian milk. The methods involve the use of i) a synthase and ii) UDP, for forming UDP-glucose, characterised in that said synthase is a sucrose synthase or a trehalose synthase and said synthase forms either glucose or fructose. The methods further may involve the purification of the produced lactose.

The lactose crystallizing and drying device comprises a rack, an upper baffle and a lower baffle are perpendicularly and fixedly connected to the two ends of a heat preservation cylinder respectively, the upper baffle is located on the side, corresponding to a hot air pipe, of a middle partition plate, the lower baffle is located on the side, corresponding to a cold air pipe, of the middle partition plate, and a plurality of fins are fixedly connected to the surface of a roller at equal intervals in the circumferential direction. And a plurality of groups of fins are arranged on the surface of the roller close to the middle partition plate along the axial direction at equal intervals. The multiple fins are fixedly connected to the surface of the roller in the circumferential direction and the axial direction, the upper baffle is arranged at the hot air end of the heat preservation barrel, and the lower baffle is arranged at the cold air end of the heat preservation barrel. The hot air and the cold air fill the space from the middle to the two ends in the heat preservation barrel, the hot air fills the space from top to bottom in the heat preservation barrel, and the cold air fills the space from bottom to top in the heat preservation barrel to overflow, so that the retention time of the hot air and the cold air in the heat preservation barrel is prolonged, heat exchange with the roller and lactose in the roller is improved, and the energy utilization rate is increased.

The spray crystallization reaction tank comprises a tank body support, a reaction tank body is connected to the tank body support, a multi-section temperature control jacket assembly is connected to the reaction tank body, a stirring motor is connected to the tank body support located at the lower end of the reaction tank body, and the multi-section temperature control jacket assembly is connected to the stirring motor. A driving shaft of the stirring motor is connected with a driving gear, a stirring shaft penetrates through a middle shaft of the bottom of the reaction tank, a driven gear is connected to the stirring shaft, the driven gear is meshed with the driving gear, a stirring connecting rod is connected to the stirring shaft, a stirring rod is connected to the stirring connecting rod, a spraying pipe is connected to the tank cover, and a flow dividing disc is connected to one end of the spraying pipe. A plurality of liquid flowing holes are formed in the flow dividing disc, spraying pipes matched with the liquid flowing holes in number are arranged on the circumference of the bottom of the flow dividing disc in an array mode, a plurality of spraying openings are formed in the spraying pipes at equal intervals, and the spraying openings face downwards. The invention can improve the quality and crystallization rate of the crystallized product.

A lactulose solution end treatment device belongs to the technical field of lactulose production related equipment, and includes a curtain type membrane solid-liquid separation device for separating aluminum hydroxide from raw material liquid, and the interception capacity of the curtain type membrane solid-liquid separation device is configured to intercept aluminum hydroxide flocculation and allow lactulose molecules to pass through. The curtain type membrane solid-liquid separation device is used to realize the filtration and separation of aluminum hydroxide, and the advantage is that the interception capacity of the organic membrane in the curtain type membrane solid-liquid separation device can make the lactulose molecules pass through, and the aluminum hydroxide flocculation is intercepted, so that the separation of the lactulose raw material liquid is realized. The lactulose solution end treatment device provided by the utility model can realize efficient separation of aluminum hydroxide in the raw material liquid, and improve the final yield of lactulose.