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34results about How to "Comply with economical synthesis" patented technology

Application of tri-silicon amine rare earth complex to catalyzing of hydroboration reaction of ketone and borane

ActiveCN106188118AMethods for Enriching Synthetic ReactionsSimple structureOrganic-compounds/hydrides/coordination-complexes catalystsCatalytic reactionsRare earth2-acetylthiophene
The invention discloses application of tri-silicon amine rare earth complex to the catalyzing of hydroboration reaction of ketone and borane. The ketone is 2-acetylfuran, 2-acetylthiophene, 2-acetonaphthone or (substituted) phenyl ketone. The application has the advantages that the tri-silicon amine rare earth complex can catalyze the hydroboration reaction of the ketone and the borane under a mild condition (room temperature) in a high activity manner, and the use amount of catalyst is only 0.1-0.5% of the molar weight of the ketone; fast reaction is achieved, yield of above 90% can be reached after the reaction the performed for 10 minutes, catalyst use amount is lowered while yield is increased as compared with an existing catalyzing system, reaction time is short, the reaction condition is mild, and the economic atom synthesizing requirements are well satisfied.
Owner:SUZHOU UNIV

Application of trisilazane-rare earth complex in catalysis of hydroboration reaction between aldehyde and borane

The invention discloses application of a trisilazane-rare earth complex in catalysis of hydroboration reaction between aldehyde and borane. The trisilazane-rare earth complex disclosed by the invention can be used for catalyzing the hydroboration reaction between aldehyde and borane in a high activity manner under a mild condition (room temperature), and the dosage of a catalyst is only 0.1%-0.5% of molar ratio of aldehyde; the reaction speed is very high, the yield higher than 90% can be achieved after 10 minutes of reaction; compared with existing catalytic systems, the application has the advantages that the dosage of the catalyst is reduced, the yield is increased, the required time is short, the reaction condition is mild, and atom economy synthesis is highly met.
Owner:ZHANGJIAGANG INST OF IND TECH SOOCHOW UNIV +1

Application of n-butyllithium for catalyzing hydroboration of imine and borane

The invention relates to application of n-butyllithium and specifically relates to application of n-butyllithium for catalyzing a hydroboration of imine and borane. In the application, a catalyst, theborane and the imine are sequentially mixed uniformly, a reaction is performed on the mixture for 1-2h, the mixture is exposed to air to terminate the reaction, and the pressure of reaction liquid isreduced to remove a solvent, so as to obtain borate with different substituent groups. The n-butyllithium disclosed by the invention can be used for catalyzing the hydroboration of the imine and theborane in high activity under a room temperature condition, the dosage of the catalyst is 4-5mol% of the molar weight of the imine, and the yield of the reaction can reach above 90%. Compared with theexisting catalytic system, the application utilizes the commercialized reagent n-butyllithium, so that reaction conditions are mild, and the yield of the borate with the different substituent groupsunder limited conditions can reach 99%.
Owner:SUZHOU UNIV

Method for preparing alcohol compound by using aromatic carboxylic acid based on n-butyllithium

The invention relates to the application of n-butyllithium, in particular to a method for preparing an alcohol compound by using aromatic carboxylic acid based on the n-butyllithium. The method comprises the following steps: uniformly stirring and mixing a catalyst, borane and carboxylic acid for reaction, then exposing the mixture to air to terminate the reaction; removing a solvent from a reaction liquid at a reduced pressure, and adding silica gel methanol for hydrolysis to obtain the alcohol compound. The n-butyllithium disclosed in the invention can catalyze, with high activity, the hydroboration of carboxylic acid and borane at a room temperature, and the use amount of the catalyst is only 0.5 mol percent of the molar amount of the carboxylic acid; compared with an existing catalyticsystem, the method has the advantages that a commercial reagent n-butyllithium is used, the reaction conditions are mild, and the yields of boric acid esters with different substituents under definedconditions can be up to 90 percent or above.
Owner:SUZHOU UNIV

Method for preparing alcoholic compound from anilino lithium compound as catalyst

The invention relates to an application of an anilino lithium compound, in particular to a method for preparing an alcoholic compound from the anilino lithium compound as a catalyst. The catalyst, borane and carboxylic acid are stirred and mixed uniformly, subjected to a reaction and exposed to air to terminate the reaction, a reacted liquid is subjected to reduced-pressure treatment for solvent removal, silica gel and methanol are added, and the alcoholic compound is obtained by hydrolysis. The anilino lithium compound can perform high-activity catalysis on the reaction between carboxylic acid and borane at room temperature, dose of the catalyst is only 0.8mol% of the mole ratio of carboxylic acid, compared with the conventional catalysis system, the commercial reagent anilino lithium compound is used, reaction conditions are mild, and yield of borate with different substituents under limit conditions can reach 90% or higher.
Owner:SUZHOU UNIV

Application method of sodium triethyl borohydride, organic amine compound and preparation method of organic amine compound

The invention discloses an application method of sodium triethyl borohydride, an organic amine compound and a preparation method of the organic amine compound. The application method comprises the steps of taking sodium triethyl borohydride as a catalyst for carrying out hydroboration reaction on an amide compound and a borohydride to obtain the organic amine compound. The catalyst can perform hydroboration reduction on three different amides, namely, primary amide, secondary amide and tertiary amide to obtain various organic amine salts, and has the advantages of high catalytic activity, mild reaction conditions, simple and controllable reaction process, high reaction yield, simple post-treatment and low cost.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

Application of 4-methoxyaniline lithium in catalysis of hydroboration reaction of imine and borane

The invention relates to an application of 4-methoxyaniline lithium, and concretely relates to an application of 4-methoxyaniline lithium in the catalysis of a hydroboration reaction of imine and borane. A catalyst, borane and imine are stirred and mixed uniformly, the obtained mixture is reacted for 1-2 h, and is exposed to air to terminate the reaction, and the obtained reaction solution undergoes reduced pressure solvent removal to obtain borate with different substituent groups. The 4-methoxyaniline lithium can highly actively catalyze the hydroboration reaction of imine and borane at roomtemperature, the use amount of the catalyst is only 4-5% of the molar quantity of the imine, and the reaction yield can reach 90% or above. Compared with existing catalysis systems, the system in theinvention, using the simple 4-methoxyaniline lithium, has mild reaction conditions, and allows the yield of the borate with different substituent groups under optimized conditions to reach 99%.
Owner:ZHANGJIAGANG INST OF IND TECH SOOCHOW UNIV +1

Method for preparing aliphatic alcohol at room temperature

The invention relates to a method for preparing aliphatic alcohol at room temperature. The catalyst, borane and carboxylic acid are stirred and mixed in sequence, reacted for 50 to 60 minutes, exposed to the air to terminate the reaction, the reaction solution is decompressed to remove the solvent, and silica gel and methanol are added. , carry out the hydrolysis reaction to obtain aliphatic alcohols with different substituents. The anilinolithium compound disclosed in the present invention can catalyze the hydroboration reaction of carboxylic acid and borane with high activity at room temperature, and the amount of catalyst is only 0.6 mol% of the molar amount of carboxylic acid. Compared with the existing catalytic system, the use of A commercial reagent anilinolithium compound is developed, the reaction conditions are mild, and the yields of aliphatic alcohols with different substituents are high under limited conditions.
Owner:SUZHOU UNIV

Method for preparing boric acid ester based on n-butyl lithium

The invention relates to application of n-butyl lithium, in particular to a method for preparing boric acid ester based on the n-butyl lithium. The method comprises the following steps: sequentially stirring a catalyst, borane and carboxylic acid, uniformly mixing and reacting for 40 to 50 minutes; exposing to the air for termination reaction; depressurizing reaction liquid and removing a solventto obtain the boric acid ester with different substituent groups. The n-butyl lithium disclosed by the invention can realize high-activity catalysis of hydroboration of carboxylic acid and borane at room temperature; the use amount of the catalyst is only 0.5 mol percent of the molar amount of carboxylic acid. Compared with an existing catalytic system, the boric acid ester utilizes a commercial reagent n-butyl lithium, and reaction conditions are mild; the yield of the boric acid ester with different substituent groups reaches 99 percent under limited conditions.
Owner:SUZHOU UNIV

Applications of anilino lithium in catalytic hydroboration reaction of imine and borane

The invention relates to applications of anilino lithium, and more specifically relates to applications of anilino lithium in catalytic hydroboration reaction of imine and borane. According to a method, a catalyst, borane, and imine are stirred to be uniform, are reacted for 1 to 2h, and are exposed in the air to stop reaction, an obtained reaction solution is subjected to pressure reduction treatment to remove the solvent so as to obtain boric acid esters with different substituent groups. According to the method, anilino lithium is capable of catalyzing hydroboration reaction of imine and borane at room temperature with high activity, the catalyst using amount is only 4 to 5 mol% of the molar amount of imine, reaction yield is as high as 90% or higher. Compared with conventional catalytic systems, the advantages are that: simple anilino lithium is used, reaction conditions are mile, and the yield of boric acid esters with different substituent groups at optimized conditions is capable of reaching 99%.
Owner:SUZHOU UNIV

Application of 4-Methoxyanilino Lithium in Catalytic Hydroboration of Imines and Boranes

The invention relates to an application of 4-methoxyaniline lithium, and concretely relates to an application of 4-methoxyaniline lithium in the catalysis of a hydroboration reaction of imine and borane. A catalyst, borane and imine are stirred and mixed uniformly, the obtained mixture is reacted for 1-2 h, and is exposed to air to terminate the reaction, and the obtained reaction solution undergoes reduced pressure solvent removal to obtain borate with different substituent groups. The 4-methoxyaniline lithium can highly actively catalyze the hydroboration reaction of imine and borane at roomtemperature, the use amount of the catalyst is only 4-5% of the molar quantity of the imine, and the reaction yield can reach 90% or above. Compared with existing catalysis systems, the system in theinvention, using the simple 4-methoxyaniline lithium, has mild reaction conditions, and allows the yield of the borate with different substituent groups under optimized conditions to reach 99%.
Owner:ZHANGJIAGANG INST OF IND TECH SOOCHOW UNIV +1

Application of p-methylaniline lithium in catalysis of hydroboration reaction of imine and borane

The invention relates to an application of p-methylaniline lithium, and concretely relates to an application of p-methylaniline lithium in the catalysis of a hydroboration reaction of imine and borane. A catalyst, borane and imine are stirred and mixed uniformly, the obtained mixture is reacted for 1-2 h, and is exposed to air to terminate the reaction, and the obtained reaction solution undergoesreduced pressure solvent removal to obtain borate with different substituent groups. The p-methylaniline lithium can highly actively catalyze the hydroboration reaction of imine and borane at room temperature, the use amount of the catalyst is only 4-5% of the molar quantity of the imine, and the reaction yield can reach 90% or above. Compared with existing catalysis systems, the system in the invention, using the p-methylaniline lithium, has mild reaction conditions, and allows the yield of the borate with different substituent groups under optimized conditions to reach 99%.
Owner:NANTONG TEXTILE & SILK IND TECH RES INST +1

Application of p-tolylanilide Lithium in Catalytic Hydroboration of Imine and Borane

The invention relates to an application of p-methylaniline lithium, and concretely relates to an application of p-methylaniline lithium in the catalysis of a hydroboration reaction of imine and borane. A catalyst, borane and imine are stirred and mixed uniformly, the obtained mixture is reacted for 1-2 h, and is exposed to air to terminate the reaction, and the obtained reaction solution undergoesreduced pressure solvent removal to obtain borate with different substituent groups. The p-methylaniline lithium can highly actively catalyze the hydroboration reaction of imine and borane at room temperature, the use amount of the catalyst is only 4-5% of the molar quantity of the imine, and the reaction yield can reach 90% or above. Compared with existing catalysis systems, the system in the invention, using the p-methylaniline lithium, has mild reaction conditions, and allows the yield of the borate with different substituent groups under optimized conditions to reach 99%.
Owner:NANTONG TEXTILE & SILK IND TECH RES INST +1

Room temperature fatty alcohol preparation method

The invention relates to a room temperature fatty alcohol preparation method. According to the preparation method, a catalyst, borane, and a carboxylic acid are evenly mixed to carry out reactions for50 to 60 minutes, then the system is exposed to the air to stop the reactions, the reaction liquid is subjected to reduced pressure distillation to remove the solvent, and then silica gel and methanol are added to carry out hydrolysis reactions to obtain fatty alcohols with different substitutes. An anilino lithium compound can efficiently catalyze the hydroboration reactions between a carboxylicacid and borane at a room temperature, the catalyst only accounts for 0.6 mol% of the carboxylic acid, compared with a conventional catalyst system, a commercial reagent namely the anilino lithium compound is adopted, the reaction conditions are mild, and the yield of fatty alcohols with different substitutes is high under restricted conditions.
Owner:SUZHOU UNIV

Application of Lithium Anilide in Catalytic Hydroboration of Imine and Borane

The present invention relates to the application of anilinolithium, in particular to the application of anilinolithium in catalyzing the hydroboration reaction of imine and borane. Stir and mix the catalyst, borane and imine in sequence, react for 1 to 2 hours, and expose to the air to terminate the reaction, remove the solvent from the reaction solution under reduced pressure, and obtain boric acid esters with different substituents. The anilinolithium disclosed in the present invention can catalyze the hydroboration reaction of imine and borane with high activity at room temperature, the amount of catalyst is only 4-5 mol% of the molar weight of imine, and the reaction can reach a yield of more than 90%. , compared with the existing catalytic system, the simple anilinolithium is used, the reaction conditions are mild, and the yield of borate esters with different substituents can reach 99% under optimized conditions.
Owner:SUZHOU UNIV

N-butyl lithium based fatty alcohol preparation method

The invention relates to an n-butyl lithium based fatty alcohol preparation method. In an inert gas atmosphere, borane and aliphatic carboxylic acid are mixed, then n-butyl lithium taken as the catalyst is added to carry out hydroboration reactions; and after the hydroboration reactions, silica gel and methanol are added to carry out hydrolysis reactions to obtain the fatty alcohols. N-butyl lithium can efficiently catalyze the hydroboration reactions between carboxylic acids and borane at a room temperature, the used catalyst only accounts for 0.2 mol% of the carboxylic acids, compared with aconventional catalyst system, a commercial catalyst namely n-butyl lithium is adopted, the reaction conditions are mild, and the yield of fatty alcohols with different substitutes under restricted conditions is high.
Owner:SUZHOU UNIV

Application of o-methoxyanilinolithium in Catalytic Hydroboration of Imines and Boranes

The invention relates to the application of o-methoxyanilino lithium, in particular to the application of o-methoxyanilino lithium in catalyzing the hydroboration reaction of imine and borane. Stir and mix the catalyst, borane and imine in sequence, react for 1 to 2 hours, and expose to the air to terminate the reaction, remove the solvent from the reaction solution under reduced pressure, and obtain boric acid esters with different substituents. The o-methoxyanilinide lithium disclosed in the present invention can catalyze the hydroboration reaction of imine and borane with high activity at room temperature, and the amount of catalyst is only 4-5 mol% of the molar weight of imine, and the reaction can reach 90% The above yield, compared with the existing catalytic system, utilizes simple o-methoxyanilinide lithium, the reaction conditions are mild, and the yield of borate esters with different substituents can reach 99% under optimized conditions.
Owner:NANTONG TEXTILE & SILK IND TECH RES INST +1

Catalyst for amination synthesis of carbodiimide, synthesis method and obtained guanidyl compound

The invention discloses a catalyst for amination synthesis of carbodiimide, a synthesis method and an obtained guanidyl compound. The catalyst is lithium triethylborohydride. The catalyst disclosed by the invention has the characteristics of low cost, easiness in obtaining, low toxicity, greenness and the like; the high-purity guanidyl compound can be obtained by the synthesis method; and the synthesis method is simple in process, high in yield, high in atom economy and low in energy consumption.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY
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