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Enteral nutrition emulsion for tumor patient

An enteral nutrition emulsion, a technology for tumor patients, applied in the directions of medical raw materials derived from fish feed, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. Reduce and other problems to achieve the effect of enhancing antioxidant capacity, reducing damage and promoting recovery

Active Publication Date: 2009-02-11
SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently commercially available enteral nutrition mainly improves malnutrition by providing comprehensive nutritional support to patients, thereby enhancing immunity. However, most tumor patients are affected by side effects after surgery, radiotherapy and chemotherapy. The acceptance ability of the patient is reduced, and the adjuvant treatment effect of nutritional support is poor

Method used

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  • Enteral nutrition emulsion for tumor patient
  • Enteral nutrition emulsion for tumor patient
  • Enteral nutrition emulsion for tumor patient

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Purchased 30g of sea cucumber polysaccharide from Beijing Jinjiuge Technology Co., Ltd., 70g of pearl oyster meat powder from Guangzhou Xingyi Marine Bioengineering Co., Ltd., 20g of spirulina powder from South China Sea Institute of Oceanology, Chinese Academy of Sciences, and Beijing Jinxiu Xindi Haoyun Trading Co., Ltd. Co., Ltd. purchased 7 mL of olive oil, 5 g of gum arabic from Beijing Gremont International Trade Co., Ltd., 0.8 g of agar gum from Zhongke Seaweed Development Co., Ltd., and tragacanth gum from Quanzhou Lvbao Green Food Co., Ltd. 0.8g.

[0020] Dissolve agar gum and tragacanth gum in boiling water first, filter with gauze and stir while hot, then add warm water to a concentration of 2%.

[0021] Dissolve sea cucumber polysaccharides, pearl oyster meat powder, spirulina powder and gum arabic in 500mL of water, then add agar gum and tragacanth mucilage, then add olive oil dropwise, add water to 1000mL, ultrasonically emulsify for 15min, fill, seal, and...

Embodiment 2

[0024] Take fresh and live sea cucumbers, wash them, remove the sediment and viscera, freeze them at -22°C for 6-8 hours, slice them with a shear, put them in a meat grinder and grind them, add 4 times the volume of normal saline and mash them with a tissue grinder broken. Adjust the pH to 7.0, add neutral protease, incubate at 50°C for 8 hours, boil at 90-100°C to kill the enzyme for 10 minutes, centrifuge the enzymolysis solution to remove the precipitated supernatant, concentrate in vacuo, add ethanol with a volume fraction of 95% to The volume fraction of ethanol in the system is 60%, put it in a refrigerator at 4°C overnight, collect the precipitate by centrifugation, decolorize with activated carbon, degrease with ethanol, remove protein by Saveg method, put it in a refrigerator at 4°C overnight, collect the precipitate by centrifugation, wash, dialyze, and vacuum freeze Dried to obtain 50 g of sea cucumber polysaccharide.

[0025] 50g of pearl oyster meat powder was pu...

Embodiment 3

[0030] Prepare abalone polysaccharide 40g by the method for embodiment 2. 65g of soybean protein powder was purchased from Henan Shuguang Biotechnology Co., Ltd., 15g of spirulina powder was purchased from the South China Sea Institute of Oceanology, Chinese Academy of Sciences, 6mL of olive oil was purchased from Beijing Shengchun Guomei Trading Co., Ltd. Co., Ltd. purchased 2g of gum arabic, 0.5g of agar gum, and 0.5g of tragacanth gum.

[0031] Dissolve agar gum and tragacanth gum in boiling water first, filter with gauze and stir while hot, then add warm water to a concentration of 2%.

[0032]Dissolve sea cucumber polysaccharide, soybean protein powder, spirulina powder and gum arabic in 500mL water, then add agar gum and tragacanth mucilage, then add olive oil dropwise, add water to 1000mL, ultrasonically emulsify for 10min, fill, seal, 135°C The enteral nutrition emulsion of the present invention was obtained by instant ultra-high temperature sterilization for 15 secon...

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Abstract

The invention relates to an enteral nutrition emulsion used for tumor patients, which is characterized in that the emulsion of every 1000mL contains 30g to 50g of holothurian amylase, abalone amylase, oyster amylase or meretrix amylase, 50g to 70g of pearl oyster meat powder, soybean protein powder or fish protein powder, 15g to 25g of spirulina powder, 6ml to 8 ml of olive oil, 3g to 8g of an emulsifier and water of rest amount. The enteral nutrition emulsion can improve the activity of free radical scavenger enzymes of the organism, enhance the oxidation resistance of tissues and adjust the immune function so as to ensure the increasing trends of the weight, the upper-arm circumference and the skin fold thickness of the brachial triceps muscle of a sufferer, and gradually normalize various blood biochemical indicators, thereby reducing damages caused by operation or radiotherapy and chemotherapy to the immune system, being capable of providing nutritional supports for the tumor patients of head and neck cancer, esophageal cancer, pancreatic cancer, liver cancer, and the like as well as the tumor patients who accept radiotherapy and chemotherapy, and promoting the recovery of the patients.

Description

technical field [0001] The invention relates to an enteral nutrition agent, in particular to an enteral nutrition emulsion containing marine biological polysaccharide suitable for cancer patients. Background technique [0002] Nutritional supplementation is a focus of comprehensive cancer treatment. Cancer patients often suffer from malnutrition due to their increased energy consumption and insufficient intake of nutrient substrates, resulting in a decline in their immune function, while patients receiving radiotherapy and chemotherapy may experience adverse reactions in the digestive tract, nausea, vomiting, etc., leading to The body presents obvious negative nitrogen balance, hypoproteinemia, hyperlipidemia and hyperglycemia. Therefore, effective enteral nutrition supplementation for cancer patients can maintain the immune function of the intestinal mucosal barrier and viscera, and reduce infection complications and sepsis. Compared with parenteral nutrition, enteral nut...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/63A61K38/02A61K47/36A61P3/02A61K35/60A61K35/56A61K31/715A23L33/00A23L33/125A61K35/616A61K35/618
Inventor 孙恢礼蔡冰娜吴园涛孙小钰张偲
Owner SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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