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Medicine for treating osteoporosis and preparing method thereof

An osteoporosis and drug technology, applied in the field of pharmaceutical preparations, can solve the problems of uncertain absorption of trace elements, dependence and side effects, unexplained etiological significance, etc., achieving no toxic side effects, definite curative effect, and short treatment course Effect

Inactive Publication Date: 2015-07-08
赵振荣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(3) Calcitonin (CT) deficiency: after menopause, the level of CT decreases, which may contribute to the occurrence of osteoporosis due to the weakening of factors that inhibit bone resorption
(4) The role of other hormones: Some data show that patients with primary osteoporosis have abnormal secretion of thyroid hormones, glucocorticoids, growth hormones, life factors (especially growth interferon C), and gastrin, but Its etiological significance has not been elucidated
[0011] However, Western medicine treatment: the absorption of trace elements is uncertain, affects appetite, treats the symptoms but not the root cause, is not conducive to treatment, and often has dependence and side effects

Method used

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  • Medicine for treating osteoporosis and preparing method thereof
  • Medicine for treating osteoporosis and preparing method thereof

Examples

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preparation example Construction

[0084] When the dosage form of the drug is a tablet, its preparation method includes the following steps:

[0085] In the first step, the raw materials of the drug are mixed in proportion, and ethanol with an alcohol concentration of 85%-95% relative to the mass of the mixture is added 3 to 5 times, heated to reflux for 4 to 6 hours, extracted, and filtered to obtain the first extraction The dregs obtained by filtration are then added to ethanol with an alcohol concentration of 90%-95% relative to the mass of the dregs 2 to 4 times, heated to reflux for 1 to 3 hours, extracted and filtered to obtain a second extract; The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0086] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer and pulverized for 1 to 3 hours, crushed, and sieved to obtain ultrafine powder of 400 mesh to 500 mesh;

[00...

Embodiment 1

[0095] Example 1 Granules

[0096] The preparation process of the granules of the present invention is: 150g of aconite, 300g of Himalayan Mirabilis, 220g of cornus, 300g of bellflower, 400g of medlar, 220g of deer kidney, 250g of dodder, 350g of actinidia, 150g of cowpea, 320g of kudzu mushroom, Fushen 220g, Ceratophyllum 320g, Cyperus rotundus 150g, Daigou 350g, Polygala 220g, Ziheche 150g, Jujube seed 350g, Tibetan fennel 140g, Longan meat 220g, Magnolia officinalis 330g, Ganoderma lucidum 250g, Alisma orientalis 300g, Antler cream 200g , Polygonum multiflorum 120g, Yangshen 320g, Ejiao 200g, Cordyceps 400g, Pleurotus ostreatus 150g and Agrimonia 300g;

[0097] Step 1: Mix the raw materials according to the stated ratio, add 7 times the alcohol concentration of 90% ethanol to the mixture, heat to boil and reflux for 4 hours, filter, and use percolation at a rate of 2ml per minute. Percolate, collect the percolate, then concentrate it to a paste with a relative density of 1.04 a...

Embodiment 2

[0099] Example 2 Tablets

[0100] The preparation process of the tablet of the present invention is: 200g of aconite, 150g of Himalayan jasmine, 220g of cornus, 300g of bellflower, 200g of medlar, 310g of deer kidney, 300g of dodder, 250g of actinolite, 200g of cowpea, 150g of kudzu mushroom, Fushen 240g, Ceratophyllum 150g, Cyperus rotundifolia 220g, Daigo 350g, Polygala 150g, Ziheche 200g, Jujube seed 350g, Tibetan fennel 150g, Longan meat 300g, Magnolia officinalis 330g, Ganoderma lucidum 220g, Alisma orientalis 300g, Deer horn cream 250g , Polygonum multiflorum 100g, Yangshen 320g, Ejiao 140g, Cordyceps 420g, Pleurotus ostreatus 200g and Agrimonia 350g;

[0101] In the first step, the raw materials of the drug are mixed in proportions, and ethanol with an alcohol concentration of 95% is added, which is 4 times the mass of the mixture, heated to reflux for 5 hours, extracted and filtered to obtain the first extract; the dregs obtained by filtering Then add ethanol with an alcoh...

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Abstract

The invention discloses medicine for treating the osteoporosis and a preparing method thereof. The medicine is made of radix aconiti lateralis preparata, Himalaya mirabilis jalapa, dogwood, rust-coloured crotalaria herbs with roots, barbary wolfberry fruits, deer kidneys, semen cuscutae, actinolite, cowpea, japanese balanophora, poria with hostwood, pyrola, rhizoma cyperi, finest cream, polygala tenuifolia, human placenta, spina date seeds, caraway, longan aril, mangnolia officinalis, lucid ganoderma, rhizoma alismatis, cornu cervi degelatinatum, polygonum multiflorum, Tibetan hawksbeard roots, colla corii asini, cordyceps sinensis, oyster-cap fungus, hairyvein agrimony, deer tails, fruits of highland barley malt, acanthopanax, fructus alpiniae oxyphyllae, cibotium barometz, eucommia ulmoides and fructus psoraleae. The medicine has the advantages that the effect of invigorating the spleens and the kidneys is achieved, and the effects of strengthening kidney qi, warming and invigorating kidney yang, strengthening tendons and bones, tonifying qi and augmenting force are achieved at the same time; in addition, the medicine can tonify qi, nourish blood, regulate qi-flowing for strengthening the spleens, enhance resistance and have the advantages of being rapid in effect taking, high in efficiency, exact in treatment effect, short in treatment course, free of toxic and side effects, low in price and the like in the aspect of treating the osteoporosis.

Description

Technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis is a group of bone diseases caused by multiple reasons. The bone tissue has normal calcification, the calcium salt and the matrix are in a normal ratio, and the metabolic bone disease is characterized by a decrease in the amount of bone tissue per unit volume. In most osteoporosis, the reduction of bone tissue is mainly due to increased bone resorption. The onset is usually slow and individual is quicker. The biochemical examination is basically normal, characterized by bone pain and easy fracture. Pathological anatomy showed that the cortical bone was thin, and the trabecula was sparse and atrophied and the osteoid layer was not thick. Osteoporosis, primary osteoporosis is a systemic bone disease characterized by decreased bone mass and deterioratio...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P19/10A61K33/26A61K35/20A61K35/50A61K35/32A61K35/36A61K35/48
Inventor 侯丽君赵振荣
Owner 赵振荣
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