Probiotic tablets based on lactobacillus plantarum and preparation method of probiotic tablets

A technology of Lactobacillus plantarum and probiotic tablets, which is applied in the food field, can solve the problems of obvious differences in individual intestinal flora and physiological state, and achieve the reduction of serum leptin levels, weight loss, serum total cholesterol and triglycerides horizontal effect

Pending Publication Date: 2020-09-29
HANGZHOU WAHAHA TECH +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effects of these different probiotics are strain-specific, and individual intestinal flora and physiological state are significantly different, and the same probiotic may not be applicable to all individuals
Therefore, there is still a need to develop more new strains of probiotics that can control body weight and reduce fat accumulation to fill the gaps of existing strains (although most new strains themselves also have specificity, there may be such a situation: existing strains have specific effects on An individual does not work and the new strain happens to work)

Method used

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  • Probiotic tablets based on lactobacillus plantarum and preparation method of probiotic tablets
  • Probiotic tablets based on lactobacillus plantarum and preparation method of probiotic tablets
  • Probiotic tablets based on lactobacillus plantarum and preparation method of probiotic tablets

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preparation example Construction

[0080] The preparation method of described plantarum lactobacillus freeze-dried powder comprises the following steps:

[0081] 1) Preparation of medium: the medium is an improved MRS medium, and its formula is glucose 20-30g, beef extract 10-13g, tryptone 5-7g, soybean peptone 5-7g, yeast powder 5-6g, acetic acid Sodium 3-5g, diammonium hydrogen citrate 1-2g, dipotassium hydrogen phosphate 2-3g, magnesium sulfate 0.4-0.6g, cysteine ​​hydrochloride 0.4-0.7g, Tween-80 1-2mL, Manganese sulfate hydrate 0.2-0.25g, water 1000mL; adjust its pH to 6.5±0.2;

[0082] 2) Preparation of bacterial strain protective agent: the formula of the bacterial strain protective agent is skim milk 80g / L, trehalose 100g / L, glycerin 20g / L;

[0083] 3) Inoculate Lactobacillus plantarum and / or its mutants in the fermentation substrate with 5%-10% inoculation amount to carry out fermentation culture, the fermentation temperature is 34-38°C, the fermentation time is 13-18h, and the pH of the fermentation ...

Embodiment 1

[0097] A probiotic tablet based on Lactobacillus plantarum, including 10 parts of Lactobacillus plantarum 1701 freeze-dried powder, 5 parts of tea theanine, 20 parts of konjac powder, 63.95 parts of direct-pressed auxiliary materials, 0.05 parts of vitamin C, stearic acid Magnesium 1 part. The number of viable bacteria in the lyophilized powder of Lactobacillus plantarum 1701 is 3×10 9 CFU / g. The direct-compression auxiliary material is direct-compression maltitol.

[0098] The Lactobacillus plantarum 1701 was isolated from yogurt powder samples collected from the villages of Shigatse City, Tibet Autonomous Region, my country, and was deposited in the General Microbiology Center of the China Committee for the Collection of Microbial Cultures on October 23, 2019, with a preservation number of CGMCC 18728. The microbial taxonomy is named Lactobacillus plantarum.

[0099] The preparation method of Lactobacillus plantarum 1701 comprises:

[0100] 1) The preparation of medium, d...

Embodiment 2

[0118] A probiotic tablet based on Lactobacillus plantarum 1701, including 4 parts of Lactobacillus plantarum 1701 freeze-dried powder, 10 parts of tea-theanine, 10 parts of konjac powder, 75.5 parts of direct-pressed auxiliary materials, 0.2 parts of vitamin C, stearin Magnesium acid 0.3 part. The number of live bacteria of the plant Lactobacillus 1701 is 1×10 11 CFU / g. The direct-pressing auxiliary material is direct-pressing sorbitol.

[0119] The Lactobacillus plantarum 1701 was isolated from yogurt powder samples collected from the villages of Shigatse City, Tibet Autonomous Region, my country, and was deposited in the General Microbiology Center of the China Committee for the Collection of Microbial Cultures on October 23, 2019, with a preservation number of CGMCC 18728. The microbial taxonomy is named Lactobacillus plantarum.

[0120] The preparation method of Lactobacillus plantarum 1701 comprises:

[0121] 1) The preparation of medium, described medium, is the impr...

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Abstract

The invention relates to the field of foods, and discloses probiotic tablets based on lactobacillus plantarum and a preparation method of the probiotic tablets. Lactobacillus plantarum freeze-dried powder, tea leaf theanine, konjaku flour, direct compression auxiliary materials, vitamin C and magnesium stearate are compounded, the direct compression auxiliary materials are adopted, and a direct compression technique is adopted, so that process flows for granulation and the like can be omitted, and the energy consumption can be reduced, the productivity can be increased, and the properties of the tablets can also be improved notably. The probiotic tablets can reduce weight, reduce in vivo fat accumulation, reduce ratio of internal organs of the body and body fat ratio, reduce leptin level and reduce blood lipid, and can be used for preventing and treating obesity. In addition, lactobacillus plantarum 1701 contained in the tablets also has favorable tolerance and adhesion property. The bacterial strains after being inactivated also have the function of reducing weight, so that products containing the bacterial strains are good in stability and long in quality guarantee period.

Description

technical field [0001] The invention relates to the field of food, in particular to a probiotic tablet based on Lactobacillus plantarum and a preparation method thereof. Background technique [0002] Obesity is mainly due to the disorder of the body's energy metabolism balance, resulting in energy intake exceeding energy consumption, resulting in excessive accumulation of body fat, resulting in metabolic diseases. Obesity is not only affected by multiple factors such as genetics, environment, metabolism, and physiology, but is also associated with diseases such as hyperlipidemia, hypertension, diabetes, insulin resistance, hyperuricemia, non-alcoholic fatty liver, and coronary atherosclerotic heart disease. Closely related. At present, obesity and its complications have become a major public health problem worldwide, which not only affects the appearance of individuals, but also poses serious hazards to human health. [0003] At present, a large number of studies have show...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61K9/20A61K47/12A61P3/06A61P3/04C12N1/20A61K35/747A61K31/198C12R1/25
CPCA61K9/2013A61K31/198A61K35/747A61K36/888A61P3/04A61P3/06C12N1/20A61K2300/00
Inventor 葛红娟任学良孙盛陈苏李言郡俞赟霞翁璐溦郑志瑶陈彩玲陈作国陈丽娥朱珺
Owner HANGZHOU WAHAHA TECH
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