Anti-dandruff and itching-relieving shampoo

A technology for anti-dandruff, anti-itch and shampoo, applied in the field of shampoo, can solve the problems of low conversion rate of 2-chloro-N-oxypyridine, difficulty in oxidation of pyridine chloride, low oxidation efficiency, etc., and achieve high oxidation conversion rate , Good anti-dandruff and anti-itch effect, high conversion rate

Active Publication Date: 2021-12-03
浙江领康企业管理有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] It can be clearly seen that the oxidation of 2-chloropyridine is the basic step for preparing ZPT, and its oxidation time is usually 3-5h, and those skilled in the art know that it is difficult to oxidize pyridine, and it is more difficult to oxidize chlorinated pyridine, so by Chloropyridine is converted to its conversion rate of 2-chloro-N-oxypyridine. The conversion rate of 2-chloro-N-oxypyridine is low. For example, Qiu Tao supported phosphotungstic acid to catalyze the synthesis of 2-chloropyridine-N-oxide. The experiment uses the impregnation method to prepare SiO 2 Supported phosphotungstic acid catalyst, with 2-chloropyridine as raw material, H 2 o 2 2-chloropyridine-N-oxide was synthesized as an oxidant, and the effects of phosphotungstic acid loading, catalyst dosage, reactant ratio, reaction temperature, and reaction time on the oxidation reaction were discussed. The optimal process conditions were: phosphotungsten The load of acid is 30%, the amount of catalyst is 3.3%, n(2-chloropyridine):n(H 2 o 2 )=1:6.0, the reaction temperature is 80 o C; the reaction time is 30h, and the yield is as high as 89.8%. It can be clearly seen that the use of traditional catalysts to oxidize 2-chloropyridine not only has a long oxidation time, but also has extremely low oxidation efficiency, which needs to be improved

Method used

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preparation example Construction

[0079] The preparation method of the gas diffusion electrode is as follows:

[0080] (1) Preparation of diffusion layer: Mix ammonium bicarbonate, 27.5wt.% PTFE emulsion, and glycerin aqueous solution to obtain a suspension, and then mix the suspension on the pretreated carbon nanotube powder to obtain The paste is rolled and formed, then raised to 245°C at 1°C / min in a muffle furnace, kept at a constant temperature for 35min, and cooled naturally to obtain a 275μm diffusion layer. The mass and dosage of the ammonium nitrate, PTFE emulsion, and carbon nanotube powder The ratio is (15):(65):(55), the dosage of the glycerin aqueous solution is 1.75ml, and the volume ratio of glycerol to water is 1.75:1.

[0081] (2) Pretreatment of the metal mesh layer: the nickel foam was washed sequentially with 0.035M hydrochloric acid, acetone, and deionized water, and then vacuum-dried at 105° C. for 5.5 hours to obtain a metal mesh layer.

[0082] (3) Prepare the catalyst layer: dissolve ...

Embodiment 1

[0088] An antidandruff and antipruritic shampoo prepared by the following method:

[0089] (A) 5wt.% lauryl ammonium sulfate, 13wt.% ammonium laureth sulfate, 5wt.% cocamidopropyl hydroxysultaine, 1wt.% carbon chain number C8-C14 according to the mass ratio Alkyl polyglucoside and 1wt.% ethylene glycol monostearate were dispersed in deionized water, heated and stirred evenly, and kept at a constant temperature of 70°C.

[0090] (B) Dissolve 0.75 wt.% polyquaternium-10 and 0.4wt.% polydimethylsiloxane in deionized water according to the mass ratio, add it to the solution obtained in step (A), stir evenly, and cool down to a constant temperature 50°C.

[0091] (C) Dissolve 2 wt.% zinc pyrithione, 0.05 wt.% Cathone, 1wt.% essence and 1wt.% amino acid in deionized water according to the mass ratio, add to the solution obtained in step (B), and stir evenly , cooling down to a constant temperature of 35°C.

[0092] (D) Add an appropriate amount of sodium chloride to the solution ...

Embodiment 2

[0094] An antidandruff and antipruritic shampoo prepared by the following method:

[0095] (A) 6wt.% lauryl ammonium sulfate, 14.5wt.% ammonium lauryl ether sulfate, 5.5wt.% cocamidopropyl sulfobetaine, 1.25wt.% carbon chain number C8-C14 alkyl polyglucosides and 1.1wt.% ethylene glycol monostearate were dispersed in deionized water, heated and stirred evenly, and kept at a constant temperature of 72.5°C.

[0096] (B) Dissolve 1.1wt.% polyquaternium-10 and 0.45 wt.% polydimethylsiloxane in deionized water according to the mass ratio, add to the solution obtained in step (A), stir evenly, and cool down to a constant temperature 52.5°C.

[0097] (C) Dissolve 3 wt.% zinc pyrithione, 0.075wt.% Cathone, 1.1 wt.% essence and 1.25wt.% amino acid in deionized water according to the mass ratio, add to the solution obtained in step (B), and stir After uniformity, the temperature was lowered to a constant temperature of 37.5°C.

[0098] (D) Add an appropriate amount of sodium chloride...

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Abstract

The invention provides anti-dandruff and itching-relieving shampoo. According to the anti-dandruff and itching-relieving shampoo, the shampoo with high foamability, stability, proper viscosity and small irritation to scalp is obtained by compounding anionic, cationic, amphoteric and nonionic surfactants, chloropyridine oxide is catalyzed through diffused oxygen, the conversion rate of the chloropyridine oxide is improved, and the process is extremely short in time consumption, on the premise of maintaining high conversion rate and selectivity, the production efficiency is remarkably improved, the purity and conversion rate of the product are further improved when a shampoo anti-dandruff antipruritic agent ZPT is prepared, and the heavy metal content of ZPT is smaller than 3.5 ppm.

Description

technical field [0001] The invention belongs to a shampoo, and in particular relates to an anti-dandruff and anti-itch shampoo. The anti-dandruff and anti-itch agent is high-purity zinc pyrithione, which is used to inhibit and kill fat-loving fungi on the scalp, and especially relates to In the preparation of shampoo or conditioner additive. Background technique [0002] There are some fungal communities in the head skin of normal people. Among them is a kind of Malassezia, which belongs to the unicellular yeast fungus, called Pityrosporum. This kind of bacteria exists widely on human skin. Malassezia may be It can cause skin inflammations such as seborrheic dermatitis, folliculitis, and tinea versicolor. According to reports, at least seven different species of Malassezia have been found in human sebum, including Malassezia globosa, Malassezia symphysis and Malassezia restrictans, etc., and these seven species of Malassezia have six The species is lipophilic bacteria, amo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/58A61K8/44A61K8/46A61K8/86A61Q5/02A61Q5/00C25B3/05C25B3/07C25B3/09C25B3/11C25B3/23C25B11/032C25B11/052C25B11/095
CPCA61K8/58A61K8/463A61K8/86A61K8/442A61Q5/02A61Q5/006C25B3/23C25B3/11C25B3/07C25B3/09C25B3/05C25B11/032C25B11/095C25B11/052A61K2800/596A61K2800/83
Inventor 邱志新
Owner 浙江领康企业管理有限公司
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