The invention discloses a vascular basis-brain connection and cognitive behavior model construction method based on fMRI. The method comprises the following steps: S1, preprocessing
brain function magnetic
resonance data by using SPM12 and NIT; S2, finding out a
gradient analysis and hierarchical function connection difference
brain region as a
region of interest, and extracting a gradient value and a hierarchical function connection value corresponding to the
region of interest; S3, depicting a vascular aging state by using a
kidney medulla R2<*> value; S4, collecting the
score of a tested behavior
cognition test; S5, performing Pearson's
correlation analysis on the functional connection value of the
region of interest and indexes for depicting the vascular aging, and performing Pearson'scorrelation analysis on the functional connection value of the region of interest and the
score of the behavior
cognition test; and S6, carrying out Pearson
correlation analysis on the indexes of thevascular aging and the scores of the behavior
cognition test. According to the invention, based on functional magnetic
resonance, a
brain aging research model of vascular basis-brain connection-cognitive behaviors is constructed from the perspective of a hierarchical network, and new evidences are provided for understanding of a
brain aging function connection mechanism.