The invention relates to a photocatalytic wastewater degradation device capable of immediately warning the tendency of titanium oxide particle agglomeration, belonging to the technical field of wastewater treatment. The following problems exist in the prior related art: the microwave energy is wasted, the single-tank wastewater treatment capacity is smaller, the internal high cyclic strength is insufficient, the bubble rising path is shorter, the oxygen supply concentration ratios in key areas are insufficient, the catalyst particle interception link is weaker, the degradation reaction endpoint is difficult to distinguish, catalyst agglomerates can not be dispersed in situ by strong force, and occurrence of catalyst agglomeration can not be perceived immediately. The invention aims at the problems. The structure of the device limits the microwave irradiation airspace, allows substantial capacity expansion of the reactor, is favorable for reinforcing supply of air atmosphere in the key degradation reaction areas, is suitable for finely intercepting the catalyst particles, can disperse the catalyst agglomerates in situ by strong force, simultaneously carries out ultrasonic cleaning on quartz tubes incidentally, can automatically and immediately turn off the related power supply when the degradation reaction reaches the endpoint, and can warn the tendency of catalyst agglomeration.