32 results about "Premature ventricular complex" patented technology

The present invention provides one medicine composition for treating coronary heat disease ventricular premature beat based on the Chinese medicine theory of benefiting vital energy, nourishing Yin, promoting blood circulation, dredging meridian, clearing away heat-evil in the pericardium and tranquilizing. The medicine composition has 12 kinds of Chinese medicinal materials including ginseng, ophiopogon root, dogwood, red sage, common jujube seed, etc. The pharmacological test shows that the composite medicine capsule has obvious effect of preventing mouse's arrhythmia caused by CaCl2 and decreasing the sustained time of rat's arrhythmia caused by aconitine.

The invention discloses a method for generating a template and detecting a premature beat, and a device. The method comprises the following steps: sequentially and respectively putting M waveforms for measuring a heart beating in N templates relative to the waveforms by sequentially performing a relativity comparison between the waveforms for measuring the heart beating and the N templates, wherein N is less than M; and taking the template which obtains most heart beating times from the first template to the N template as a normal template. The method for detecting the premature beat comprises the following steps: pretreating an inputted electrocardiogram signal to obtain a pretreated signal; extracting the feather parameters of the heart beating for measuring from the pretreated signal, wherein the feather parameters include the width of a QRS wave, an existing RR interphase and a related average RR interphase; obtaining the waveform of the heart beating for measuring from the pretreated signal, and calculating the association coefficient between the waveform of the heart beating for measuring and the waveform of the template; and according to judging conditions that whether the association coefficient between the waveform for measuring the heart beating and the waveform of the template is less than a set threshold and whether the feather parameters are deviated from normal values, judging whether a ventricular premature beat exists.

The present invention relates to identifying and using groups of cardiac events associated with depolarization wavefronts to coordinate the delivery of pacing therapy to the heart. According to one aspect of the invention, cardiac events associated with a plurality of cardiac sites are detected. The cardiac sites may be located in a single heart chamber or in bilateral heart chambers. A group of detected cardiac events associated with a depolarization wavefront is identified. According to another aspect of the invention, a particular cardiac event of an identified group associated with a depolarization wavefront may be used to synchronize pacing therapy delivered to the heart. According to yet another aspect, premature ventricular contractions may be classified using the identified groups.

Techniques identify origins of ventricular arrhythmias (e.g., ventricular tachycardia or premature ventricular complexes) including exit sites or other sites using a single or multi-lead electrocardiogram (ECG) assembly. The ECG assembly is used to map an organ into a series of different three-dimensional (3D) regions. Pace maps or ventricular arrhythmia signals are used in form of ECG signals along with a supervised learning methods to pinpoint the potential origin of VT, i.e., exit sites, in the various regions.

A dual-chamber cardiac pacemaker comprising an atrial detection unit which is adapted to detect electrical signals in the atrium of a heart as atrial sense events, a ventricular detection unit which is adapted to detect electrical signals of a ventricle of the heart as ventricular sense events, a stimulation unit which is adapted at least to trigger the delivery of electrical pulses to the ventricle as ventricular stimulation events, and a control unit which is connected to the atrial and the ventricular detection units and the stimulation unit and adapted to control triggering of the delivery of pulses in dependence on the atrial detection unit and the ventricular detection unit in such a way that pulse delivery to the ventricle is triggered after the expiry of an AV time after detection of an atrial sense or stimulation event if prior to expiry of the AV time no ventricular sense event is detected by the ventricular detection unit, wherein the control unit is further adapted to divide ventricular sense events into at least two categories of which a first category concerns ventricular sense events to be associated with natural stimulus conduction from the atrium to the ventricle while a second category concerns ventricular sense events to be associated with ventricular extrasystoles or premature ventricular contractions (PVC) and control of the cardiac pacemaker is differentiated in accordance with whether a ventricular sense event is or is not associated with the first category, characterized in that for the control of triggering of pulse delivery an AV monitoring interval is provided in such a way that the AV monitoring interval is triggered by each atrial sense event which is outside an atrial refractory time, wherein the cardiac pacemaker is adapted to associate ventricular events occurring within the AV monitoring interval to the first category.

A method and apparatus for using vagal stimulation to detect autonomic tone and assess a patient's risk of sudden cardiac death (SCD) are presented. The method involves stimulating the patient's vagus nerve in order to induce a drop in arterial blood pressure, which simulates the patient's cardiovascular response to a premature ventricular contraction (PVC). Sinus rhythm data just before and immediately following the stimulation is recorded and analyzed for a degree of heart rate turbulence (HRT) in order to detect abnormalities in autonomic tone and assess the risk of SCD. In an embodiment, the method is implemented in an implantable cardiac device (ICD), which can deliver arrhythmia prevention therapy based on the risk of SCD. The method can assess the patient's vagal activity on-demand by measuring HRT without relying on naturally occurring PVCs and eliminates the risk of causing arrhythmia associated with artificially inducing PVCs in order to measure HRT.

The invention relates to an identification method for the premature beat in a dynamic electrocardiogram. The method comprises the following steps that 1) according to the detected position of the heartbeat, an inputFeature is extracted; 2) inputFeatures of the sinus heartbeat, the supraventricular premature beat heartbeat and the ventricular premature beat heartbeat are extracted from an electrocardiosignal database labelled with the known heartbeat type and merged into training data; 3) corresponding inputFeatures are extracted from all heartbeats of the dynamic electrocardiogram to be analyzed and merged into test Data; 4) a supervised learning algorithm is adopted for pre-classifying the test Data, the corresponding heartbeat types are output, and position information of the sinus heartbeat is extracted; 5) a certain number of pre-classified sinus heartbeats are selected and averaged, and a template of a sinus QRS composite wave is obtained; 6) by adopting an expert system based onsimilarity measurement, ECG forms and RR intervals, the supraventricular premature beat and the ventricular premature beat are judged. The method is suitable for identification of the ventricular premature beat and the supraventricular premature beat of long-time electrocardiogram data of the dynamic electrocardiogram and effectively assists doctors in making related diagnosis quickly.

A system and method for automatically detecting abnormal heart contractions originating in the ventricles, in a way that is independent of signal morphology is provided. As an uninterrupted series of ventricular detections indicates a possible ventricular arrhythmia, all ventricular beats are detected including isolated premature ventricular contractions (PVCs) and the associated R-R intervals are corrected. Premature ventricular contractions (ectopic beats) in non-standard lead configuration in a noisy signal from an ambulatory subject from a low-cost sensor that may be a small form factor sensor with 1 inch lead separation and may be rotated through multiple placements to correct an R-R interval time series used to detect atrial fibrillation.

An implantable cardiac stimulation device provides selective atrial pacing upon detection of a premature ventricular complex (PVC). The device comprises a premature ventricular complex detector that detects premature complexes of the heart, and a sensing circuit that senses atrial events. The device further comprises a P wave discriminator that identifies an atrial event sensed by the sensing circuit following detection of a premature ventricular complex as one of a retrograde P wave and a normal sinus P wave, and an atrial pulse generator that delivers an atrial pacing pulse responsive to the discriminator identifying an atrial event sensed by the sensing circuit following detection of a premature ventricular complex as a retrograde P wave.

The present invention discloses one kind of Chinese medicine preparation for treating arrhythmia and its preparation process and quality control method. The Chinese medicine preparation is dripping pill prepared with five kinds of Chinese medicinal materials, including Dangshen, solomoseal, notoginseng, amber and spikenard. The quality control method for the Chinese medicine preparation includes the thin layer discrimination of notoginseng and spikenard, the checking of the dissolution, and the measurement of notoginseng. The Chinese medicine preparation has the functions of invigorating qi, nourishing yin, eliminating palpitate and restoring pulse. It is used in treating arrhythmia, ventricular premature beat and other cardiac and cerebral vascular diseases, and has the features of simple preparation process, high effective component extracting rate, high curative effect, etc.

The present invention provides one medicine composition for treating coronary heat disease ventricular premature beat based on the Chinese medicine theory of benefiting vital energy, nourishing Yin, promoting blood circulation, dredging meridian, clearing away heat-evil in the pericardium and tranquilizing. The medicine composition has 12 kinds of Chinese medicinal materials including ginseng, ophiopogon root, dogwood, red sage, common jujube seed, etc. The pharmacological test shows that the composite medicine capsule has obvious effect of preventing mouse's arrhythmia caused by CaCl2 and decreasing the sustained time of rat's arrhythmia caused by aconitine.

The invention discloses a ventricular premature beat identification method and a ventricular premature beat identification device based on an improved convolution neural network. The method comprisesthe following steps of: pretreating electrocardiosignal; cutting the electrocardiosignal into a plurality of heartbeat sequences, and extracting an RR interval between each heartbeat and a previous heartbeat; calculating a kurtosis value and bias value of each heartbeat sequence; inputting the above items into an improved convolution neural network model, outputting an identification result of a heartbeat to be identified, and judging whether the heartbeat to be identified is a ventricular premature heartbeat or not. The method adopts the improved convolution neural network, comprehensively considers a waveform characteristic of the heartbeat and the relationship between the heartbeat and the previous heartbeat, and automatically judges whether a certain heartbeat is a ventricular premature heartbeat or not, so that the judgment accuracy can be greatly improved. The improved convolution neural network consists of a convolution layer, a pool layer and a full-connection layer, wherein the full-connection layer is connected with specific characteristics of ventricular premature beats and sends the characteristics to a classifier after fusion calculation for automatically judging the ventricular premature beats.

A method of mapping arrhythmic activity, such as premature ventricular contraction (“PVC”) activity, using an electroanatomical mapping system includes defining at least two arrhythmia template signals. Electrophysiology data points, each including an electrophysiological signal, are collected. A morphological similarity between the electrophysiological signal and a first arrhythmia template signal is computed; if this exceeds a preset threshold, then the electrophysiology data point is added to a corresponding arrhythmia map. If it does not, a morphological similarity between the electrophysiological signal and a second arrhythmia template signal is computed. If this exceeds the preset threshold, then the electrophysiology data point is added to a corresponding arrhythmia map. If neither exceeds the preset threshold, then the electrophysiology data point can be used to establish an additional arrhythmia map by defining an additional arrhythmia template signal.

The invention belongs to the medical preparation, in particular to a Chinese herbal preparation- <BI QI WAN> capsules for treating coronary heart disease. The medicine is prepared by Fructus Trichosanthis, Rhizoma Pinelliae, Bulbus Allii Macrostemi and Radix Notoginseng. The invention is used for treating coronary heart disease and angina for 43 cases, acute left heart insufficiency and pneumonedema for 21 cases, acute arrhythmia such as auricular fibrillation, multi-source multi-type ventricular premature beats, ventricular tachycardia, ventricular fibrillation and severe nodal bradyrhythmia for 36 cases, all 100 cases, effective 88 cases and the general effective rate 88 percent.

The embodiment of the invention discloses a location and recognition method and device of ventricular premature beats. The method includes the following steps that a target electrocardiogram ECG is input into a pre-constructed ventricular premature beat location and recognition model which is obtained on the basis of electrocardiogram samples and convolution neural network training; the portion, corresponding to the origin part of premature beats in the heart, of each electrocardiogram sample is pre-labeled; based on the output result of the ventricular premature beat location and recognitionmodel, the portion, corresponding to the origin part of premature beats in the heart, of a target electrocardiogram is judged. According to the embodiment, the ventricular premature beat location andrecognition model is constructed for identification of the target electrocardiogram, the portion, corresponding to the origin part of premature beats in the heart, of the target electrocardiogram is judged, and the problems are solved that in the prior art, the artificial recognition efficiency is low and not accurate.

The invention relates to a traditional Chinese medicine for treating ventricular premature beat. The traditional Chinese medicine is characterized by being prepared from the following important raw materials by a conventional method: 9-15g of processed Radix Glycyrrhizae, 10-30g of Radix Codonopsis (Codonopsis pilosula and / or Codonopsis tangshen), 10-30g of Poria cocos, 10-20g of Atractylodes macrocephala, 10-20g of Angelica sinensis, 10-20g of Radix Polygalae (Polygala tenuifolia and / or Polygala sibirica), 15-40g of Os Draconis, 15-40g of Concha Ostreae, 3-9g of Schisandra chinensis fruit, 6-12g of Dimocarpus longan pulp, 6-12g of Aucklandia lappa, 6-12g of Semen Persicae (Prunus persica and / or Prunus davidiana), 9-15g of Carthamus tinctorius flower, 10-20g of Salvia miltiorrhiza, and 9-15g of Radix Puerariae (Pueraria lobata and / or Pueraria thomsonii). The traditional Chinese medicine provided by the invention has effects of supplementing qi, nourishing yin, regulating the flow of qi, smoothing collaterals, relieving anxiety and palpitation, warming and invigorating the heart-yang, promoting blood circulation and dispelling blood stasis, and has the advantages of simple preparation, easy-accessible raw materials, quick action, low cost and high cure rate. Through clinical application and test, the cure rate is 31.25% and the total effective rate is up to 90.62%.

The invention provides a cardiac pace making system which comprises a perception module and a control module. When the perception module senses that an atrial event is missed between the current ventricular event and a previous ventricular event, or an AV (atrioventricular) interval is beyond a first standard range, or a VV interval is less than a second standard interval, the control module determines the current ventricular event as a ventricular premature beat event. Therefore, the ventricular premature beat event can be recognized systematically in detail, and detailed diagnostic information can be provided to help medical care personnel to better known a patient condition and make a reasonable therapeutic regimen. In addition, the cardiac pace making system can be used for evaluation,diagnosis and treatment of various cardiac rhythms, and allow a device to achieve improvement and innovation of the therapeutic regimen more flexibly and simply.

The invention discloses a traditional Chinese medicine composition for treating frequent ventricular premature beat. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20 parts of American ginseng, 8-15 parts of white peony roots, 20-30 parts of dried rehamnnia roots, 10-20 parts of poria cocos, 8-15 parts of fructus schizandrae, 10-20 parts of raw hawthorns, 10-20 parts of fructus cannabis, 8-15 parts of gelatin beads, 10-20 parts of fresh gingers, 8-15 parts of jujubes, 10-20 parts of cassia twigs, 10-20 parts of radix liquiritiae, 20-35 parts of salviae miltiorrhizae, 8-15 parts of earthworms, 8-15 parts of polygala tenuifolia, 15-25 parts of pine nodular branches and 10-20 parts of radix sophorae flavescentis. The traditional Chinese medicine composition has the effects of nourishing heart-yin, assisting heart-yang, dispelling evil of sticky wet drink and resisting arrhythmia, realizes the purpose of treating frequent ventricular premature beat, and has the advantages of being stable in curative effect, short in treatment time and small in side effect.

Implantable systems, and methods for use therein, perform at least one of a cardiac assessment and an autonomic assessment. Short-term fluctuations in PR intervals, that follow the premature contractions in the ventricles, are monitored. At least one of a cardiac assessment and an autonomic assessment is performed based on the monitored fluctuations in PR intervals that follow the premature contractions in the ventricles. This can include assessing a patient's risk of sudden cardiac death (SCD), assessing a patient's autonomic tone and / or detecting myocardial ischemic events based on the monitored fluctuations in PR intervals that follow the premature contractions in the ventricles.

An implantable cardiac stimulation device and associated method perform a true or blanking period ventricular undersensing detection algorithm in response to ventricular loss of capture not associated with fusion or a change in capture threshold. The test identifies an originating cause of loss of capture, which may be ventricular undersensing of intrinsic R-waves or premature ventricular contractions occurring during a ventricular blanking period or atrial undersensing of P-waves resulting in blanking period ventricular undersensing. A corrective action is taken to reduce the likelihood of blanking period ventricular undersensing by automatically adjusting device operating parameters. The corrective action may include automatic adjustment of atrial sensitivity, shortening of the ventricular blanking period, or adjustment of the base stimulation rate. Minimizing the blanking period ventricular undersensing improves device performance by avoiding back-up stimulation and minimizing the risk of pacemaker competition-induced arrhythmias.

The invention discloses an ECGI-based method for locating abnormal activation points of premature ventricular contractions. This method establishes a joint acquisition framework of 64-lead body surface potential data and computed tomography imaging to obtain a personalized heart-trunk model. Through Tikhonov Regularization solves the electrocardiographic inverse problem and reconstructs the epicardial potential to accurately locate the abnormal activation point of premature ventricular contractions, which has important practical application value.