The invention belongs to the medication technical field, which discloses the medicine and the preparation method for treating the heart disease. The medicine is mainly prepared by ginseng root, turmeric root tuber, danshen root and liquorice, or ginseng root, turmeric root tuber, danshen root, liquorice and semen lepidii being assigned by certain weight ratios. The invention can be made to any type of medicament that can be accepted by the clinic or pharmacology, which is the good quality oral preparation. The medicine has effects of Qi supplementing and pulse rocovering, and clots absorbing and collaterals clearing, and can be used to treat deficiency of Qi and Yin, palpitation and dyspnea caused by retention of excessive fluid, chest distress and flustering, premature beat, tachycardia and coronary heart disease, and the effect is outstanding.