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52results about How to "Few effect" patented technology

Peptides that inhibit complement activation

The present invention relates to compositions, including pharmaceutical compositions that inhibit complement activation, and contain amino acid sequences X1-X2-X3-W-E-X4-X5-X6 and / or Z1-C1-Z2-P-Z3-Z4-C2-Z5 as described. The invention further relates to methods of inhibiting complement activation in vivo or ex vivo by administering a pharmaceutical composition as described herein.
Owner:BAXALTA GMBH

Pharmaceutical composition, methods for treating and uses thereof

The present invention relates to certain SGLT-2 inhibitors for treating and / or preventing oxidative stress, for example in patients with type 1 or type 2 diabetes, as well as to the use of such SGLT-2 inhibitors in treatment and / or prevention of cardiovascular diseases in patients, for example type 1 or type 2 diabetes patients. The present invention further relates to certain SGLT-2 inhibitors for treating and / or preventing a metabolic disorder and preventing, reducing the risk of or delaying the occurrence of a cardiovascular event in patients, for example patients with type 1 or type 2 diabetes.
Owner:BOEHRINGER INGELHEIM INT GMBH

Pharmaceutical composition, methods for treating and uses thereof

The present invention relates to certain SGLT-2 inhibitors for treating and / or preventing oxidative stress, for example in patients with type 1 or type 2 diabetes, as well as to the use of such SGLT-2 inhibitors in treatment and / or prevention of cardiovascular diseases in patients, for example type 1 or type 2 diabetes patients. The present invention further relates to certain SGLT-2 inhibitors for treating and / or preventing a metabolic disorder and preventing, reducing the risk of or delaying the occurrence of a cardiovascular event in patients, for example patients with type 1 or type 2 diabetes.
Owner:BOEHRINGER INGELHEIM INT GMBH

Treatment of mastalgia with 4-hydroxy tamoxifen

ActiveUS20050032909A1Reduce painFew effectBiocideAntipyretic4 hydroxy tamoxifenMammary gland
A method of treatment comprises administering 4-hydroxy tamoxifen percutaneously to a patient having mastalgia. The 4-hydroxy tamoxifen may be formulated in a hydroalcoholic gel or an alcoholic solution.
Owner:BESINS HEALTHCARE LUXEMBOURG (LU)

Pharmaceutical composition comprising an sglt2 inhibitor and a ppar- gamma agonist and uses thereof

The invention relates to a pharmaceutical composition comprising an SGLT2 inhibitor and a PPARγ agonist which is suitable in the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia. In addition the present invention relates to methods for preventing or treating of metabolic disorders and related conditions.
Owner:BOEHRINGER INGELHEIM INT GMBH

Image processor, image processing method and image processing program

An image processing method and an image processor for drawing the movements of such linear objects as fur, hair, and grass of a turf being influenced by wind have not been proposed thus far. The present invention provides image processing method executed by an image processor for projecting and drawing linear objects viewed from view point on a two-dimensional plane when the view point, ground, and linear objects, of which one end of each linear object is fixed on the ground, are positioned in virtual three-dimensional space, comprising a drawing step of layering the cross-sections of linear objects created by cutting the plurality of linear objects at planes which are parallel with the ground for each of planes as semi-transparent layers, and a redrawing step of moving the semi-transparent layers in a predetermined direction after a predetermined time elapsed and redrawing the semi-transparent layer(s) on the two-dimensional plane.
Owner:SEGA CORP

Transdermal drug delivery devices containing O-Desmethyl Venlafaxine (ODV) or its salts

InactiveUS20070053968A1Simple and convenient and non-invasive administrationFast deliveryOrganic active ingredientsBiocideVasomotor symptomSerotonin
The present invention provides transdermal drug delivery devices (i.e., patches) comprising O-desmethylvenlafaxine (ODV), a selective serotonin and norepinephrine re-uptake inhibitor, or a pharmaceutically acceptable salt thereof, which, among other, offer the advantage of eliminating or reducing the adverse side effects associated with the oral administration of ODV. Also provided are methods of preparing and using these transdermal delivery systems for the treatment of depression, anxiety disorders, vasomotor symptoms and pain.
Owner:WYETH LLC

Platinum(II) and platinum(IV) complexes and their use

Platinum(II) complexes are provided selected from the group consisting of compounds of the general formulae I to IV and physiologically acceptable addition salts thereof, wherein the radicals R1 to R4, R1′ to R3′, X, X′, Y, a, i, k and n are defined as in the description, and mixtures of the compounds for use as prophylactic and / or therapeutic agents for the treatment of diseases, and cytostatic platinum complexes with the general formulae[PtII(NH3)n(A)n(Z)2-n] or [PtIV(NH3)n(A)n(Z)2-nX2]and[PtII(A)1(Z)2] or [PtIV(A)1(Z)2X2]wherein A, Z and n are as defined in the description.
Owner:FAUSTUS FORSCHUNGS CIE TRANSLATIONAL CANCER RES

Pharmaceutical composition, methods for treating and uses thereof

The present invention relates to certain SGLT-2 inhibitors for treating and / or preventing oxidative stress, for example in patients with type 1 or type 2 diabetes, as well as to the use of such SGLT-2 inhibitors in treatment and / or prevention of cardiovascular diseases in patients, for example type 1 or type 2 diabetes patients. The present invention further relates to certain SGLT-2 inhibitors for treating and / or preventing a metabolic disorder and preventing, reducing the risk of or delaying the occurrence of a cardiovascular event in patients, for example patients with type 1 or type 2 diabetes.
Owner:BOEHRINGER INGELHEIM INT GMBH

Antiviral phosphinate compounds

The invention is related to anti-viral phosphinate compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
Owner:GILEAD SCI INC

Methods and Compositions for Treatment of Macular and Retinal Disease

InactiveUS20070259843A1Convenient treatmentImprove efficacyBiocideSenses disorderExudative age-related macular degenerationDisease cause
The present invention describes linking a therapeutic agent to a compound which is known to be naturally concentrated in a tissue affected by, or that is causing, a disease, to create a prodrug for treatment of the disease. Embodiments of the present invention include a new class of carotenoid-linked drugs to treat such blinding retinal disease such as age-related macular degeneration, retinoblastoma, and diabetic macular edema. For example, the present invention comprises a method for the treatment of a disorder of the eye comprising linking a therapeutic agent to a xanthophyll carotenoid to create a prodrug, and administering a therapeutically effective amount of the prodrug to an individual in need of treatment. Provided are prodrugs for treatment of retinoblastoma, cystoid macular edema (CME), exudative age-related macular degeneration (AMD), diabetic retinopathy, diabetic macular edema, or inflammatory disorders.
Owner:UNIV OF GEORGIA RES FOUND INC

Method and device for determining an operating parameter of a shockwave source

In a method to determine an operating parameter of a shockwave source for the generation of a shockwave to disintegrate a calculus in a patient by a shockwave lithotripsy, a characteristic of the patient and / or of the calculus is determined before and / or during the shockwave lithotripsy and the operating parameter is automatically determined dependent on the characteristic. A device for determining an operating parameter of a shockwave source for the destruction of a calculus in a patient has an acquisition and control unit for determination and / or input of a characteristic of the patient and / or of the calculus, and for automatic determination of the operating parameter dependent on the characteristic.
Owner:SIEMENS AG

Novel Nucleic Acid Having Adjuvanticity and Use Thereof

The disclosed nucleic acid at least containing a single-stranded DNA to be delivered to endosomes of dendritic cells and a double-stranded RNA capable of activating TLR3 can be delivered to endosomal TLR3 and has a strong adjuvanticity with few side effects, and therefore is useful as an active ingredient of immunostimulants, vaccine adjuvants, cancer therapeutic agents and the like.
Owner:INST OF ADVANCED IMMUNOTHERAPY
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