Film coated tablets containing a plurality of vitamins and mineral matters, and its preparation process

A film coating and vitamin technology, which is used in medical preparations containing active ingredients, food preparation, food science, etc., can solve problems affecting drug stability and storage period, unqualified drug content uniformity, and uneven coating dispersion. and other problems to achieve the effect of clear handwriting, complete tablet and smooth surface

Inactive Publication Date: 2013-04-17
江门市新会区光华生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the inspection, only one or a few drugs will be randomly checked to test the content of active ingredients, which directly leads to the unqualified content uniformity of most drugs
And the coating of prior art also has deficiency in practical application, and medicine is easy to absorb moisture, and this directly affects the stability and storage period of medicine, and coating color is unstable, is easily oxidized and affects the character of medicine, and coating is dispersed inhomogeneously.

Method used

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  • Film coated tablets containing a plurality of vitamins and mineral matters, and its preparation process
  • Film coated tablets containing a plurality of vitamins and mineral matters, and its preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A film-coated tablet containing multiple vitamins and minerals, the unit tablet core contains the following components by weight: vitamin A 3300IU, β-carotene 2000IU, vitamin D 3 3200IU, Vitamin E 10IU, Vitamin H 60μg, Vitamin K 150μg, Vitamin C 200mg, Vitamin B 1 6.0mg, vitamin B 2 3.6mg, vitamin B 6 6.0mg, vitamin B 12 5μg, folic acid 0.64mg, nicotinamide 20mg, calcium pantothenate 25mg, potassium 15mg, iron 9mg, manganese 2.5mg, iodine 150IU, chromium 100IU, molybdenum 25IU, selenium 25IU, boron 150IU, zinc 2.5mg, choline 25mg, inositol 25mg , Taurine 15mg, calcium hydrogen phosphate 100mg, microcrystalline cellulose 210mg, HPMC 3mg, starch 70mg, silicon dioxide 35mg, sodium carboxymethyl starch 21mg, magnesium stearate 7mg, citric acid 0.7mg;

[0028] The water-soluble coating solution contains the following parts by weight: 2 parts of HPMC, 1 part of Tween-80, 1 part of PEG-400, 2 parts of talcum powder, and 94 parts of water.

[0029] The preparation proc...

Embodiment 2

[0041] A film-coated tablet containing multiple vitamins and minerals, the unit tablet core contains the following components by weight: vitamin A 2000IU, β-carotene 1800IU, vitamin D 3 2000IU, Vitamin E 15IU, Vitamin H 80μg, Vitamin K 160μg, Vitamin C 150mg, Vitamin B 1 5.0mg, vitamin B 2 5mg, vitamin B 6 10mg, vitamin B 12 6μg, folic acid 1mg, nicotinamide 30mg, calcium pantothenate 28mg, potassium 20mg, iron 5mg, manganese 6mg, iodine 160IU, chromium 90IU, molybdenum 10IU, selenium 30IU, boron 130IU, zinc 1mg, choline 26mg, inositol 30mg, taurine Acid 10mg, calcium hydrogen phosphate 150mg, microcrystalline cellulose 60mg, HPMC 3.5mg, starch 100mg, silicon dioxide 30mg, sodium carboxymethyl starch 180mg, magnesium stearate 3mg, citric acid 0.6mg;

[0042] The water-soluble coating liquid contains the following parts by weight: 1 part of HPMC, 3 parts of Tween-80, 2 parts of PEG-400, 4 parts of talcum powder, and 90 parts of water.

[0043] The preparation process o...

Embodiment 3

[0051] A film-coated tablet containing multiple vitamins and minerals, the unit tablet core contains the following components by weight: vitamin A 3800IU, β-carotene 3000IU, vitamin D 3 4000IU, Vitamin E 3IU, Vitamin H 60μg, Vitamin K 200μg, Vitamin C 120mg, Vitamin B 1 10mg, vitamin B 2 4mg, vitamin B 6 7.0mg, vitamin B 12 1μg, folic acid 0.1mg, nicotinamide 18mg, calcium pantothenate 30mg, potassium 10mg, iron 8mg, manganese 3mg, iodine 100IU, chromium 50IU, molybdenum 25IU, selenium 10IU, boron 200IU, zinc 3mg, choline 45mg, inositol 10mg, bovine Sulfonic acid 20mg, calcium hydrogen phosphate 90mg, microcrystalline cellulose 180mg, HPMC 4mg, starch 60mg, silicon dioxide 40mg, carboxymethyl starch sodium 60mg, magnesium stearate 8mg, citric acid 0.8mg;

[0052] The water-soluble coating liquid contains the following parts by weight: 3 parts of HPMC, 2 parts of Tween-80, 3 parts of PEG-400, 1 part of talcum powder, and 85 parts of water.

[0053] The preparation proc...

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Abstract

The invention discloses film coated tablets containing a plurality of vitamins and mineral matters, and its preparation process, and discloses a formula of the film coated tablets, and the main formula is divided into four parts and is performed a processing treatment with high-quality pharmaceutical excipients. The tablets of the invention have comprehensive vitamins and mineral matters, have multiple health-care efficacy, and are convenient to eat and easy to carry. The invention has the advantages of stringent technological processes, interlocked processes and convenient preparation, the prepared tablets have the uniform content with hardness of greater than and equal to 6.2kg and the friability of less than and equal to 0.2%, and is suitable for the popularization and the usage of trace compounds.

Description

technical field [0001] The invention relates to the field of medicines and health care products, in particular to a film-coated tablet containing multiple vitamins and minerals and a preparation process thereof. Background technique [0002] Vitamins A, B, C, D, E and other vitamins and iron, zinc, calcium and other minerals are important substances that are indispensable for maintaining physiological and biochemical metabolism in the human body. Among them, according to the solubility of vitamins in lipid solvents or water, they are divided into two categories: fat-soluble vitamins and water-soluble vitamins. The former includes vitamin A, vitamin D, vitamin E and vitamin K. Except for the vitamins included in the former, the rest of the vitamins are All are water soluble. Vitamin A family, vitamin C family, and vitamin E family all have strong free radical scavenging and anti-oxidation functions, and have significant effects on beauty and anti-aging, improving immunity, a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/42A61K9/28A23L1/304A23L1/302A61P3/02A61K33/32A61K33/26A61K33/24A61K33/22A61K33/18A61K33/00A61K31/714A61K31/593A61K31/51A61K31/519A61K31/525A61K31/455A61K31/4415A61K31/4188A61K31/375A61K31/355A61K31/07A61K31/05A61K31/015A61K31/197A61K31/14A61K31/047A61K31/185A23L33/15
Inventor 孙培雄
Owner 江门市新会区光华生物科技有限公司
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