Application of composition for intestinal tracts to preparation of diagnosis and treatment products for intestinal tract diseases

A technology for intestinal diseases and compositions, which is applied in the direction of medical preparations containing active ingredients, metabolic diseases, and drug combinations, etc., which can solve the problems of difficult absorption of nutrients, unfavorable preparation of intestinal cleansing, postoperative wound healing, and electrolyte imbalance in the human body and other problems, to achieve the effect of rich intestinal nutrition and abundant intestinal cleansing preparation

Pending Publication Date: 2019-12-31
麦孚营养科技(北京)有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Too low dietary fiber intake will aggravate constipation and retention, while too high intake is not conducive to intestinal cleansing preparation and postoperative wound healing
The aforementioned problems have brought great difficulties to bowel preparation for patients with constipation, and have become a long-term problem in the field of bowel cleansing and preparation
[0008] Second, patients with low intestinal cleanliness must take a large amount of laxatives to clean the intestinal tract before colonoscopy or surgery
However, the mouthfeel of oral laxatives is extremely poor, and patients who take a large amount of laxatives are prone to adverse reactions such as nausea, vomiting, abdominal distension and abdominal pain, which seriously affect the patient's compliance (Application of improved bowel preparation method in colonoscopy examination of patients with constipation, China Internal Medicine Mirror Magazine, Lu Le, Meng Xiaofen, Qu Pingmin, etc., Vol. 23, No. 7, pp. 30-34)
Moreover, a large number / combined use of laxatives damages the intestinal mucosal barrier, causing intestinal bacterial translocation and intestinal infection, causing serious problems such as electrolyte imbalance and nutrient loss in the human body, and increasing the treatment burden of patients and medical insurance expenses
[0009] Third, intestinal cleansing preparations require patients to restrict their diet the day before surgery, resulting in insufficient intake of energy, protein, vitamins, minerals and other nutrients
[0011] Fifth, the patient's gastrointestinal function is weakened after intestinal examination and surgery, and the digestion and absorption capacity decreases accordingly
[0014] CN103431391A discloses a full nutritional formula powder and its preparation method. The formula contains dietary fiber, which leads to insufficient intestinal cleansing, and a large amount of laxatives need to be administered in combination to meet the relevant requirements for intestinal cleansing preparation
[0018] CN1290443C records a kind of enteral complete nutritional emulsion, which is mainly suitable for patients with nutritional intake disorders. The protein component is mainly derived from casein preparations with slow absorption and high cost, which makes it difficult for patients to absorb nutrients. , prone to indigestion, flatulence and other symptoms after taking it

Method used

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  • Application of composition for intestinal tracts to preparation of diagnosis and treatment products for intestinal tract diseases
  • Application of composition for intestinal tracts to preparation of diagnosis and treatment products for intestinal tract diseases
  • Application of composition for intestinal tracts to preparation of diagnosis and treatment products for intestinal tract diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Example 1 Low-residue full-nutrition formula 1

[0069] In every 1000g of the product in this example, as vitamins, it contains: 1.8g of sodium L-ascorbate, 0.23g of nicotinamide, 0.0023g of folic acid, 0.5g of dl-α-tocopheryl acetate, 0.1g of calcium D-pantothenate, and 0.17g of riboflavin g, pyridoxine hydrochloride 0.32g, thiamine hydrochloride 0.02g, retinyl acetate 0.06g, cholecalciferol 0.03g, phytonadione 0.0007g, cyanocobalamin 0.00007g, D-biotin 0.00016g.

[0070] In each 1000g product of this embodiment, as minerals, containing: ferrous sulfate 0.2g, zinc sulfate 0.2g, magnesium sulfate 15g, manganese sulfate 0.02g, potassium iodate 0.002g, copper sulfate 0.007g, sodium selenite 0.0006 g, 27g of potassium citrate, 7.2g of sodium citrate, 12g of potassium chloride, 4g of calcium hydrogen phosphate, 3.4g of sodium chloride and 2g of calcium carbonate. These minerals were mixed evenly with 20g of maltodextrin as embedding agent.

[0071] The amount of raw mater...

Embodiment 2

[0073] Example 2 Low-residue full-nutrient formula products 2

[0074] In every 1000g of the product in this example, as vitamins, it contains: 1.2g of sodium L-ascorbate, 0.18g of nicotinamide, 0.0017g of folic acid, 0.4g of dl-α-tocopheryl acetate, 0.07g of D-calcium pantothenate, and 0.1g of riboflavin g, pyridoxine hydrochloride 0.2g, thiamine hydrochloride 0.012g, retinyl acetate 0.04g, cholecalciferol 0.03g, phytonadione 0.0005g, cyanocobalamin 0.00006g, D-biotin 0.00012g.

[0075] In every 1000g of the product in this embodiment, as minerals, it contains: ferrous sulfate 0.15g, zinc sulfate 0.15g, magnesium sulfate 13g, manganese sulfate 0.015g, potassium iodate 0.001g, copper sulfate 0.005g, sodium selenite 0.0004 g, 25g of potassium citrate, 6.5g of sodium citrate, 11g of potassium chloride, 3.6g of calcium hydrogen phosphate, 2.8g of sodium chloride and 1.8g of calcium carbonate. These minerals were mixed evenly with 20g of maltodextrin as embedding agent.

[0076...

Embodiment 3

[0078] Example 3 Low-residue full-nutrient formula products 3

[0079] Every 1000g of the product in this example contains, as vitamins: 1g of sodium L-ascorbate, 0.1g of nicotinamide, 0.001g of folic acid, 0.25g of dl-α-tocopheryl acetate, 0.06g of calcium D-pantothenate, and 0.1g of riboflavin , pyridoxine hydrochloride 0.2g, thiamine hydrochloride 0.012g, retinyl acetate 0.04g, cholecalciferol 0.02g, phytonadione 0.0005g, cyanocobalamin 0.00006g, D-biotin 0.0001g.

[0080] In every 1000g of the product in this embodiment, as minerals, it contains: ferrous sulfate 0.1g, zinc sulfate 0.2g, magnesium sulfate 10g, manganese sulfate 0.015g, potassium iodate 0.002g, copper sulfate 0.004g, sodium selenite 0.0005 g, 18g of potassium citrate, 5g of sodium citrate, 9g of potassium chloride, 2.8g of calcium hydrogen phosphate, 2.4g of sodium chloride and 1g of calcium carbonate, these minerals were mixed evenly with 20g of maltodextrin as embedding agent.

[0081]The amount of raw ...

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PUM

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Abstract

The invention relates to an application of a composition for intestinal tracts to preparation of products for increasing cleaning level of intestinal tracts of patients during examination, diagnosis and / or treatment of intestinal tract diseases. The composition for intestinal tracts is used for increasing the cleaning level of intestinal tracts of patients during examination, diagnosis and / or treatment of intestinal tract diseases, reducing the usage quantity of cathartics, reducing the generation of adverse events of the patients, enhancing the immunity of the patients, shortening the recovery period of an intestinal tract surgery, reducing the generation of intestinal tract surgery infection, stabilizing the eating rules of the patients and the like, and has quite important clinical value on increasing the clean degree of the intestinal tracts of the patients and increasing the nutrition of the intestinal tracts.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to the application of the enteric composition for preparing intestinal disease diagnosis and treatment products. Background technique [0002] Colonoscopy is widely used in the examination and diagnosis of colorectal diseases, and has become the gold standard for screening colorectal diseases and colorectal cancer. Colonoscopy is the tool of choice for screening colorectal cancer in the average-risk white population over the age of 50 in the United States. ) and other organizations (Zhao Ziye et al. The detection rate of polyps and adenomas and their age distribution in colonoscopy in the population with average risk of colorectal cancer. Chinese Journal of Digestive Endoscopy. 2014; 31(2): 64- 68). The accuracy and safety of colonoscopy and diagnosis largely depend on the preparation and quality of bowel cleansing (BaiY, FangJ, Zhao SB, et al. Impact of preprocedure simethicone on aden...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/00A61K38/01A61P3/02A61K36/899A61K31/122A61K31/194A61K31/197A61K31/215A61K31/355A61K31/375A61K31/4188A61K31/4415A61K31/455A61K31/51A61K31/519A61K31/525A61K31/593A61K31/7004A61K31/714A61K33/04A61K33/06A61K33/10A61K33/14A61K33/18A61K33/26A61K33/30A61K33/32A61K33/34A61K33/42
CPCA23L33/40A61K38/011A61K31/7004A61K36/899A61K36/28A61K36/48A61K36/31A61K36/889A61K31/215A61K31/375A61K31/455A61K31/519A61K31/355A61K31/197A61K31/525A61K31/4415A61K31/51A61K31/593A61K31/122A61K31/714A61K31/4188A61K33/26A61K33/30A61K33/06A61K33/32A61K33/18A61K33/34A61K33/04A61K31/194A61K33/14A61K33/42A61K33/10A61P3/02A23V2002/00
Inventor 郭海峰冯予春刘德恽陈璐璐
Owner 麦孚营养科技(北京)有限公司
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