3 results about "Into bladder" patented technology

The utility model discloses a kind of air spring bladder with vulcanization supporting ring composite cord structure, including bladder, the bladder is divided into bladder big head, bladder working area and bladder small head, the bladder big head part is three layer cord structure, the bladder working area and bladder small head part are single layer cord structure, and the overall thickness of bladder working area and bladder small head part is thinner than the thickness of bladder big head part, the inner diameter of bladder working area gradually decreases from bladder big head to bladder small head area, and supporting ring is fixed on the inner wall of bladder big head by vulcanization bonding mode. The air spring bladder of the utility model uses different reinforcing layer structure design, which can not only ensure the expansion outer diameter and burst pressure of the product, but also effectively reduce the product thickness of working area to improve its flexibility, reduce the air spring hysteresis force and improve the product comfort.

This invention discloses an engineered extracellular vesicle system for constructing an in situ cell factory, its preparation method, and its applications. Specifically, it involves the in situ production of drug molecules with cytotoxic effects within bladder cancer cells under urea-mediated conditions, enabling the application of a urea-mediated targeted in situ killing system for the precision treatment of bladder cancer. Leveraging the unique microenvironment of a high urea concentration of 300 mmol / L within the bladder where bladder cancer lesions are located, an engineered extracellular vesicle system, P@EV, is constructed. VR+U Through the synergistic effect of RGD tumor targeting, VSVG pH-responsive membrane fusion and UTB urea transport function, PGA-1 can be efficiently delivered into bladder cancer cells, promoting intracellular urea accumulation and in situ generation of the cytotoxic product Compound-1.

The utility model is suitable for medical consumable technical field, provide a kind of fast insertion switching type bladder irrigation tube, including catheter and conversion joint, conversion joint includes cylindrical casing, and casing one end has first pipe orifice, side wall is provided with second pipe orifice and third pipe orifice, catheter is connected with second pipe orifice, and switching core is equipped in casing.When needing to flush, directly flush connector is inserted into first pipe orifice, drives inside switching core to move, so that flush connector is communicated with second pipe orifice, and flushing fluid can enter into bladder, and flush connector is removed after flushing, and switching core is automatically reset, and second pipe orifice and third pipe orifice are automatically communicated, so that flushing waste liquid in bladder can be discharged into urine collection bag from third pipe orifice. The whole process only needs to plug flush connector, and it is simple to operate.