The invention relates to the technical field of wire saw numerical control, and provides an intelligent interface design method of a numerical control machine tool, which comprises the following steps: embedding an action button into a three-dimensional icon in a manual operation interface, and marking an adjustment direction, so that operation is more direct, and errors are prevented; integratingcommon and associated buttons into the same area, so that the operation is smoother and more efficient; adding a key component state information column so that states can be switched and parameters can be adjusted conveniently and quickly; displaying program languages and graphs in the graph editing interface in a combined manner so that editing prompts can be effectively provided for operators.The interface interactivity is high. Editing input methods are diversified. Editing operation is simplified, operation is facilitated, meanwhile, simulation machining can be conducted, execution estimation can be conducted, accidents are eliminated, the effective correctness of editing execution is improved, and misoperation is avoided. The interface distribution configuration which is simple, visual, easy to learn and use, flexible, convenient and fast to operate and capable of freely and flexibly conducting multifunctional operation adjustment is achieved.