The invention discloses a two-dimensional barcode-based logistics industry personal information privacy protection system. The system comprises a key distribution and management system, a database, a first PC (Personal Computer) side logistic management system, a first two-dimensional barcode generation and reading module, a first two-dimensional barcode reading module, a first mobile phone delivery terminal, a first mobile phone number hiding module, a third PC side logistic management system, a third two-dimensional barcode generation and reading module, a third two-dimensional barcode reading module, a third mobile phone delivery terminal and a third mobile phone number hiding module, wherein the first PC side logistic management system is positioned at a letter sending site; and the third PC side logistic management system is positioned at a receiving site. According to the two-dimensional barcode-based logistic personal information privacy protection scheme design, the two-dimensional barcode technology and an encryption technology are applied to the logistics industry to try to solve the problem of personal information leakage. The functions such as two-dimensional barcode generation and reading, sensitive information encryption protection, and key distribution and management are realized, and the problem of privacy information leakage is solved better.