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3 results about "CTLA4 Protein" patented technology
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CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.
Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof
ActiveUS12649793B2Biological material analysisImmunoglobulins against growth factorsAntiendomysial antibodiesHeavy chain
A polypeptide having a heavy chain variable region and / or light chain variable region that specifically binds to CTLA4 protein as well as antibodies and antibody fragments containing the heavy chain variable region and / or the light chain variable region that bind to CTLA4 protein. Pharmaceutical compositions and kits comprising the polypeptide or antibodies and antibody fragments containing the polypeptide are also provided.
Owner:BIOATLA LLC
A biomarker for early diagnosis of type 1 diabetes, a kit and application thereof
This invention discloses a biomarker, kit, and application for the early diagnosis of type 1 diabetes. The biomarker is CTLA4 protein and KLRD1 protein, both of which originate from the same CD4 group. + CD8 + Extracellular vesicles of double-positive T cells were analyzed, and a kit was prepared to detect CTLA4 and KLRD1 proteins for early diagnosis of type 1 diabetes. This invention screens and identifies CD4... + CD8 + The CTLA4 and KLRD1 proteins carried in the extracellular vesicles of double-positive T cells serve as early diagnostic biomarkers for type 1 diabetes, which has significant scientific and clinical value for early screening of type 1 diabetes.
Owner:JINING MEDICAL UNIV
ANTI-CTLA4 Antibodies, Antibody Fragments, Their Immunoconjugates and Uses Thereof
A polypeptide having a heavy chain variable region and / or light chain variable region that specifically binds to CTLA4 protein as well as antibodies and antibody fragments containing the heavy chain variable region and / or the light chain variable region that bind to CTLA4 protein. Pharmaceutical compositions and kits comprising the polypeptide or antibodies and antibody fragments containing the polypeptide are also provided.
Owner:BIOATLA LLC