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14 results about "FGFR Inhibition" patented technology

Inhibition of fibroblastic growth factor receptor signaling pathway activity to prevent tumor growth.

Compounds for FGFR inhibition

A compound having the following structure of Formula (IV):or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.
Owner:COGENT BIOSCIENCES INC

Compounds for FGFR inhibition

A compound having the following structure of Formula (IV):or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.
Owner:COGENT BIOSCIENCES INC

Compounds for FGFR inhibition

PCT designated stage expiredWO2025034912A9Organic active ingredientsOrganic chemistryDiseaseFGFR Inhibition
A compound having the following structure of Formula (IV): (IV) or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.
Owner:COGENT BIOSCIENCES INC

Compounds for FGFR inhibition

A compound having the following structure of Formula (IV):or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.
Owner:COGENT BIOSCIENCES INC

Compounds for FGFR inhibition

A compound having the following structure of Formula (IV): (IV) or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.
Owner:COGENT BIOSCIENCES INC

Compounds for fgfr inhibition

A compound having the structure of the following Formula (IV): (IV) or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, A, B, X, and Y are as defined herein. Also described are pharmaceutical compositions comprising the compound and uses thereof in methods of treating diseases.
Owner:COGENT BIOSCIENCES

Compounds for FGFR inhibition

PCT designated stage expiredWO2025034912A3Organic active ingredientsOrganic chemistryDiseaseFGFR Inhibition
A compound having the following structure of Formula (IV): (IV) or a stereoisomer, salt, or tautomer thereof, wherein R1, R2, R3, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.
Owner:COGENT BIOSCIENCES INC