This invention relates to the field of
pesticide residue detection technology, and provides a method for detecting
fluoride herbicide residues in
fruits and vegetables, aiming to solve the technical defects of existing detection methods, such as poor selectivity and insufficient sensitivity of adsorbents for
fluoride-containing pesticides. This method uses HFIP functionalized adsorbent as a
solid-phase extraction packing material. After activation,
sample extraction,
salting-out
centrifugation, pH adjustment, sample loading, rinsing, and
elution, quantitative detection is achieved using ultra-
high performance liquid chromatography-
tandem mass spectrometry. This invention modifies HFIP, utilizing
fluorine-
fluorine interactions,
hydrogen bonds, and hydrophobic interactions to synergistically enhance the
specific adsorption of
fluoride-containing herbicides, solving the problems of poor selectivity and insufficient sensitivity of traditional adsorbents. This method is simple to operate, has high enrichment efficiency, good
recovery and
repeatability, and a low
detection limit, making it suitable for rapid and accurate quantitative detection of fluoride herbicide residues such as
flufenacet, fluthiamethoxam,
pyrifluquinazon, and
flufenacet in cucumbers and other
fruits and vegetables.