15 results about "Urocystitis" patented technology

A method for treating a condition in a body where a biofilm on or proximate a tissue causes pain, irritation, and / or inflammation. One condition may be interstitial cystitis. The method for treating interstitial cystitis includes providing a catheter with a lumen and an elongate rod disposed within the lumen and routing the lumen through a urethra such that a distal end of the elongate rod is disposed in an interior of a bladder. Then connecting the elongate rod to a controller adapted to generate current and supplying a current at a first amperage from the controller to the distal end of the elongate rod. Applying the current for a predetermined time so as to disrupt a biofilm on or proximate to an interior wall of the bladder. A method for treating prostatitis is also disclosed.

The invention belongs to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine composition for treating radiation cystitis and a preparation method thereof. The traditional Chinese medicine composition comprises the following components: roasted rhizoma atractylodis macrocephalae, poria cocos, raw rice kernels, polyporus umbellatus, fingered citron, prepared rhizoma polygonati, pericarpium citri reticulatae, hairyvein agrimony, lalang grass rhizome, Huai wheat, lysimachia christinae hance, plantain herb and lygodium japonicum. In the formula, lysimachia christinae hance, plantain herb and lygodium japonicum have the effects of clearing heat, inducing diuresis and treating stranguria, bighead atractylodes rhizome, poria cocos, rice kernel, grifola and Huai wheat are used as auxiliary materials for tonifying spleen and promoting diuresis, hairyvein agrimony astringes to stop bleeding, lalang grass rhizome has the effects of clearing heat, inducing diuresis and stopping bleeding, prepared rhizoma polygonati has the effects of tonifying kidney essence and preparing fire with water, and all the medicines are combined to clear away the toxicity of pathogenic fire of radioactive rays on bladder meridian. The traditional Chinese medicine composition for treating radiation cystitis has the advantages of definite curative effect, few toxic and side effects and good clinical application value.

The invention provides a composition for preventing or treating acidic urinary stone of pets and application of the composition. The composition comprises citrate, N-acetylglucosamine, a corn stigma extract and a lysimachia christinae hance extract. The citrate can compete with oxalate ions and is preferentially combined with calcium ions to form a soluble calcium citrate compound, so that formation and growth of calcium oxalate crystals are inhibited, and kidney metabolic acidosis caused by improper acidification of urine is prevented. N-acetylglucosamine can repair a glycosaminoglycan layer of a bladder mucosa, reduce crystal adhesion and urethra stimulation, inhibit bacteria from adhering to the urethra, and reduce calculus and infection risks; the corn stigma extract is used for diluting the oxalic acid concentration of urine by increasing the urine volume of pets; the active ingredients of the lysimachia christinae hance extract can relieve urinary tract inflammation and smooth muscle spasm and relieve pain. The composition provided by the invention can effectively reduce formation of acidic urinary stones of pets, prevent bacterial adhesion and recurrent cystitis, and improve urinary system health of pets.

The invention discloses a traditional Chinese medicine for preventing and treating cancer and relieving pain and belongs to the field of traditional Chinese medicine preparations. The traditional Chinese medicine is prepared from 1-10 parts by weight of anoectochilus formosanus and 5-20 parts by weight of viscum walnuts, preferably 5 parts by weight of anoectochilus formosanus and 15 parts by weight of viscum walnuts. The traditional Chinese medicine composition adopts pure traditional Chinese medicine raw materials, has no toxic or side effect, and effectively improves the anti-cancer immune function of a human body, regulates the whole and organ functions of the human body and realizes the effects of inhibiting and killing cancer cells through the action principle of strengthening the body resistance, tonifying deficiency and eliminating evil. Besides, the traditional Chinese medicine can treat bronchitis, nephritis, cystitis, diabetes mellitus, black spots, freckles, age pigment, coronary heart disease, cardiovascular and cerebrovascular diseases and the like, has the effects of activating meridians to stop pain, diminishing swelling and expelling toxin, and is low in cost.

The application discloses a traditional Chinese medicine compound composition, preparation and a preparation method thereof for treating acute radiation cystitis, and belongs to the technical field of medicines. The traditional Chinese medicine compound composition for treating acute radiation cystitis is prepared based on the screening of compound components by means of modern molecular biology and the theory of traditional Chinese medicine compound, and is prepared from Lysimachia christinae 2-4 parts, Herba Epimedii 1-3 parts, Herba Patriniae 2-4 parts, Smilax glabra 2-4 parts, Sophora flavescens 0.8-2.8 parts, Lobelia 1-3 parts, Semen Lagenariae 1.4-3.4 parts, Hippophae rhamnoides 1-3 parts, Herba Erigerontis 1-3 parts and Glycyrrhiza 1-3 parts by extraction. The traditional Chinese medicine compound can solve the problems of lack of targeted mechanism intervention, limited curative effect, large side effect and poor patient compliance in the prior art; in addition, the application proposes key target points and effective components of drugs for treating acute radiation cystitis, and experiments prove that the treatment effect on acute radiation cystitis is obvious.

The invention discloses a traditional Chinese medicine compound composition for treating acute radiation cystitis, a preparation and a preparation method thereof, and belongs to the technical field of medicines. The traditional Chinese medicine compound composition for treating acute radiation cystitis is prepared by screening compound components on the basis of modern molecular biology means and combining the traditional Chinese medicine compound theory. The traditional Chinese medicine compound composition for treating acute radiation cystitis is prepared by extracting 2-4 parts of lysimachia christinae hance, 1-3 parts of herba epimedii, 2-4 parts of herba patriniae, 2-4 parts of rhizoma smilacis glabrae, 0.8-2.8 parts of radix sophorae flavescentis, 1-3 parts of Chinese lobelia, 1.4-3.4 parts of semen cuscutae, 1-3 parts of sea-buckthorn, 1-3 parts of erigeron breviscapus and 1-3 parts of liquorice. The traditional Chinese medicine compound can solve the problems of lack of targeted mechanism intervention, limited curative effect, large side effect, poor patient compliance and the like in the existing treatment; in addition, the invention provides key targets and effective components of drugs for acute radiation cystitis, and experiments prove that the pharmaceutical composition has an obvious treatment effect on acute radiation cystitis.

To provide methods and kits for identifying a companion animal having an increased risk of developing interstitial cystitis; along with compositions for treating the same.SOLUTION: A pet food composition comprises an effective amount of a fiber-bound polyphenol component, for use in increasing the level of a urinary cytokine selected from: Fms-like tyrosine kinase 3 (F1t3-L), a stem cell factor (SCF); and IL-12p40, in a companion animal.SELECTED DRAWING: Figure 1A

The invention relates to the use of epidermal growth factor for the manufacture of a medicament for the treatment of interstitial cystitis. The "epidermal growth factor" (EGF) of the invention can be used to manufacture an excellent medicament for interstitial cystitis. The medicament has a composition that includes an active ingredient, adjuvant, dispersant, wetting agent, and / or suspension agent. The carrier of the epidermal growth factor is water, colloid, hyaluronic acid, natural oils, and / or glucose. The medicament serves to reduce urinary frequency. The medicament serves to restore bladder elasticity. The medicament serves to reduce cystitis. The medicament serves to increase the antioxidant capacity in bladder tissue.The present invention proposes a novel effect of epidermal growth factor, which can be used to treat interstitial cystitis and to repair the bladder mucosa and exhibits excellent efficacy.

The invention belongs to the field of medical device technology and relates to a formulation developed for the treatment of Interstitial Cystitis disorder in particular.

The present disclosure provides a method for treating interstitial cystitis / bladder pain syndrome in a human subject in need of such treatment, comprising administering a therapeutically effective amount of a compound of formula (I) or its pharma- ceutical acceptable salt to the human subject.In certain embodiments, the method comprises administering a compound of formula (IA).

The invention discloses a bladder drainage medicine perfusion device, which belongs to the technical field of medical instruments and comprises a catheter, one end of the catheter is communicated with a urine storage bag, the other end of the catheter is communicated with the inside of the bladder through a first connecting tube, and two sides of the catheter are symmetrically communicated with medicine perfusion mechanisms. The medicine filling mechanism comprises a first connector communicated with the flow guide pipe, a one-way valve is arranged in the first connector, and the first connector is communicated with a medicine filling part. The catheter is connected with the urine storage bag and the bladder, and a drainage channel is established through the first connecting tube. Symmetrically-arranged medicine filling mechanisms are communicated with the flow guide pipe through first connectors, the one-way valves ensure that medicine flows into the bladder in a one-way mode, and backflow of urine is avoided. Continuous drug perfusion and drainage can be performed synchronously, limitation of traditional one-time perfusion is broken through, the contact time of the drug and the bladder mucosa is prolonged, and the curative effect is improved; due to the symmetrical design, bilateral drug delivery can be achieved, the drug distribution uniformity is enhanced, and the drug delivery device is suitable for tumor postoperative chemotherapy or interstitial cystitis treatment.

The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine formula with multiple effects and a preparation method of the traditional Chinese medicine formula, and the formula comprises selfheal, honeysuckle, subprostrate sophora, edible tulip, burdock, wild chrysanthemum, wild rose, coptis chinensis, radix scutellariae, dragon bone, leafhopper and liquorice. The medicine has the effects of clearing away heat and toxic materials, diminishing inflammation and swelling, killing insects and bacteria, treating and supporting cancer, removing stasis, expelling pus, inducing diuresis and the like. The traditional Chinese medicine is mainly used for treating infertility after wedding, vaginitis, cervicitis, cervical erosion, cystitis, urethritis, prostatitis, anuresis, urination stopping, endless urination, gonorrhea, venereal disease and various diseases of uterus. And the traditional Chinese medicine composition greatly shortens the treatment period and relieves the pain and economic burden of patients.

The invention belongs to the technical field of exosome application, and discloses a triptolide-loaded nano co-delivery drug delivery carrier and application thereof in preparation of drugs for treating interstitial cystitis. The triptolide-loaded nano co-delivery drug delivery carrier is used for interstitial cystitis model animals, and the following changes are observed: 1, the sensitivity of the model animals to stimulation is reduced; 2, the urination frequency of model animals is reduced, and the urination volume of words is increased; 3, the number of red blood cells in urine of the model animal is reduced; 4, bladder tissue hyperemia is relieved, and the size is reduced; and 5, the expression of inflammatory factors IL-6, MCP-1, ICAM-1 and BAX is obviously reduced. Therefore, it can be determined that the triptolide-loaded nano-co-delivery drug delivery carrier is used for treating interstitial cystitis. According to the research, the application range of the triptolide is expanded, and the triptolide is combined with the exosome to be used for treating the interstitial cystitis, so that a new thought is provided for treating the interstitial cystitis.

The invention relates to the field of pet food, in particular to traditional Chinese medicine inulin gel as well as a preparation method and application thereof. The traditional Chinese medicine inulin gel comprises a traditional Chinese medicine composition extract, a bilberry extract and inulin. The traditional Chinese medicine composition extract is obtained by extracting poria cocos, plantain herb, rhizoma alismatis and lalang grass rhizome, and the inulin is soluble dietary fibers and prebiotics. The traditional Chinese medicine inulin gel has the advantages that the gel has good palatability, traditional Chinese medicine can be continuously released in the intestinal tract through the intestinal tract retention effect, and the effective treatment time is prolonged; besides, the inulin has a certain health-care function, and the treatment effect on the cat interstitial cystitis is enhanced, so that the treatment effect can be ensured even if the feeding frequency is reduced, and the workload of pet owners and clinical care can be reduced.