The invention relates to a high-safety electronic clinical thermometer which comprises a main body, a storage mechanism, a detection head and a disinfection mechanism, the storage mechanism comprisesa storage assembly, a damping assembly and a sealing assembly, and the storage assembly comprises an air cylinder, a telescopic frame, a fixed block, a movable block and a movable plate; the damping assembly comprises an annular air bag, an air inlet pipe, an air outlet pipe, a fixing ring, a pressing ring, two connecting blocks and a plurality of first springs, the disinfection mechanism comprises a connecting box, a waste box, a discharging pipe, a fixing box, an air cylinder, a piston, a driving assembly, a first connecting pipe, a second connecting pipe, a communicating pipe and a plurality of nozzles, and the driving assembly comprises a driving plate, a driving rod and second springs. According to the high-safety electronic clinical thermometer, through the storage mechanism, the function of storing the detection head is achieved, the damage probability of the detection head is reduced, through the disinfection mechanism, the function of disinfecting the detection head is achieved, residual bacteria on the detection head are avoided, and therefore the cross infection phenomenon is avoided.