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Moisturizing and repairing bacterial cellulose mask and preparation method thereof

A technology of bacterial cellulose film and bacterial cellulose, which is applied in the field of moisturizing and repairing bacterial cellulose mask and its preparation, can solve the problems of inconvenient operation and long cycle, and achieve the effects of reducing irritation, promoting absorption, skin affinity and carrying liquid The effect of high ability

Inactive Publication Date: 2020-09-22
北京致成生物医学科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Based on this, it is necessary to provide a hair drug extraction kit, extraction method and detection method to solve the problems of long cycle and inconvenient operation of traditional extraction methods

Method used

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  • Moisturizing and repairing bacterial cellulose mask and preparation method thereof
  • Moisturizing and repairing bacterial cellulose mask and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The preparation of embodiment 1 thickener-bacterial cellulose

[0034] The fermentation culture liquid of Gluconacetobacter is selected and placed in the cultivation container, and the fermentation culture liquid of Gluconacetobacter is cultivated by the method of static cultivation. When the fermentation culture liquid of Gluconacetobacter is statically cultivated for 60 to 72 hours, the The filamentous bacterial cellulose mycelium is cultivated, and the filamentous bacterial cellulose mycelium is free in the culture medium, and the free filamentous bacterial cellulose mycelium is taken out, and after dehydration, purification and crushing, it is made into Viscous nano-scale bacterial cellulose filaments.

Embodiment 2

[0035] The synthesis of embodiment 2 bacterial cellulose (BC)

[0036] Bacterial cellulose is secreted by Gluconacetobacter (G.xylinum) strain ATCC-53582. The growth medium of this bacterial strain is HS liquid medium (Hestrin&Schramm), and its main component is: 5.0gL -1 Yeast extract, 20gL -1 Glucose, 1.5gL -1 Citric acid monohydrate, 20gL -1 Glucose and 6.8gL -1 Disodium hydrogen phosphate dodecahydrate. The culture medium was prepared with Milli-Q ultrapure water, and was sterilized by high temperature (121°C) and high pressure for 20 minutes before use. Gluconacetobacter strain ATCC53582 was inoculated into the above sterile Herstin-Schramm medium, and the volume of the inoculum solution accounted for 10% of the total medium volume. Incubate the bacterial culture inoculated with bacteria at 30 °C for 3–4 days to adjust the BC thickness in the millimeter range. Since BC is a metabolic by-product of bacterial fermentation, the thickness of the product is directly pro...

Embodiment 3

[0038] Preparation 1 of embodiment 3 moisturizing and repairing bacterial cellulose facial mask

[0039] A moisturizing and repairing bacterial cellulose mask, comprising a mask liquid and a mask base;

[0040] The facial mask liquid, its components and their mass percentages: seaweed extract 1.0%, Dendrobium candidum extract 1.5%, grape seed extract 1.0%, hyaluronic acid 0.1%, thickener 0.5%, preservative 0.2% , 5% glycerin, and the rest is deionized water.

[0041] Described facial mask base layer: the BC film of purification prepared in embodiment 2 is cut into block film (thick 0.42cm, wide 2cm, long 4cm) of the same size, and it is carried out low-temperature freeze-drying; Described low-temperature freeze-drying is The wet bacterial cellulose membrane was frozen at -20°C for 12 hours, and then vacuum freeze-dried.

[0042] The conditions for vacuum freeze-drying are: freeze the wet BC film into a solid state at -20°C, then sublimate the water in it into a gaseous state w...

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Abstract

The invention discloses a moisturizing and repairing bacterial cellulose mask and a preparation method thereof. The bacterial cellulose mask is prepared by compounding bacterial cellulose and a moisturizing and repairing mask solution. The preparation method comprises the following steps: carrying out low-temperature freeze drying treatment on a purified bacterial cellulose membrane, and infiltrating the dried bacterial cellulose membrane in the moisturizing and repairing mask solution for 24 hours to obtain the moisturizing and repairing bacterial cellulose mask. The moisturizing and repairing bacterial cellulose mask disclosed by the invention not only has good swelling property and biological safety, but also has the properties of adjusting slow release of the mask solution and improving the utilization degree of the mask solution. The mask prepared by the invention is natural and non-irritant, has moisturizing and repairing functions, and can be used for laser treatment postoperative repair.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a moisturizing and repairing bacterial cellulose mask and a preparation method thereof. Background technique [0002] Fractional laser will destroy the skin barrier function to a certain extent, lead to water loss, cause increased oil secretion, dry skin, pain, erythema and other adverse reactions. Therefore, good nursing intervention should be supplemented in wound repair after fractional laser surgery to improve patient compliance and enhance curative effect. How to deliver this active ingredient to the skin while maintaining its maximum therapeutic effect is an urgent problem to be solved. Bacterial cellulose has high mechanical strength, porosity, water content (about 98%), high hydrophilicity (a large number of hydroxyl groups), swelling rate, permeability, good air permeability, water holding capacity, in situ Plasticity, good biocompatibility and simple preparation m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61K47/38A61P17/00A61K8/02A61K8/9706A61K8/9794A61K8/9789A61K8/73A61K8/34A61Q19/00D01F2/00A61K31/728A61K31/047
CPCA61K8/0212A61K8/345A61K8/731A61K8/735A61K31/047A61K31/728A61K36/02A61K36/87A61K36/8984A61K47/38A61K2800/805A61K2800/84A61Q19/00A61K8/9706A61K8/9789A61K8/9794A61P17/00D01F2/00A61K2300/00
Inventor 刘昊李立杰覃羽邵明艳和静赵亚赛窦楠楠
Owner 北京致成生物医学科技有限公司
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