6 results about "Acetylene compounds" patented technology

The invention provides radiation sensitive compositions and substrates coated with radiation sensitive compositions wherein the composition comprises a combination of metals and / or metalloid compounds, a functionalized or unfunctionalized acetylenic compound, and other optional ingredients such as amelioration agents. The invention further provides radiation sensitive devices for detection or measurement of radiation comprising substrates coated with these radiation sensitive compositions. The radiation sensitive compositions and devices have applications in dentistry, non-destructive testing, oncology, radiology, and radiotherapy, among others.

This specification provides novel acetylene compound derivatives, compositions containing such compounds, methods for producing the sames, and uses thereof. The acetylene compound derivatives are compounds of the following chemical formula (I), or their tautomers, stereoisomers, prodrugs, crystalline forms, isotopically labeled forms, pharmaceutically acceptable salts, hydrates, or solvates. The compounds and compositions of the present invention can be used in the treatment of polθ-mediated diseases or disorders, particularly cancer. JPEG2026522774000373.jpg51149

The application belongs to the technical field of organic conjugated compounds, and particularly relates to a water-soluble arylene-acetylene luminophore containing amidine urea groups, a preparation method and application thereof. The preparation method of the water-soluble arylene-acetylene luminophore containing amidine urea groups comprises the following steps: (1) under a nitrogen atmosphere, reacting guanidino monomers, acetylenic compounds, a catalyst and a mixed solvent to obtain a reaction solution; (2) extracting the reaction solution, drying an organic phase, and performing rotary evaporation under reduced pressure to obtain a crude product, and then separating and purifying the crude product to obtain an amidine urea group arylene-acetylene compound; (3) mixing the amidine urea group arylene-acetylene compound with dichloromethane, adding trifluoroacetic acid, stirring, performing rotary evaporation under reduced pressure, washing with an organic solvent, and drying to obtain the water-soluble arylene-acetylene luminophore containing amidine urea groups. The water-soluble arylene-acetylene luminophore containing amidine urea groups obtained by the application has excellent activity, good water solubility, stable chemical properties, high sensitivity and strong selectivity.

An aminochalcone-diacetylene compound of Formula 1A:wherein R1 and R2 are independently selected from H and C1-C3 alkyl, A denotes a linkage connecting the chalcone and diacetylene units, m and n are independently integers in the range of 2 to 18, and the corresponding protonated form / ammonium salt of Formula 1B:wherein X is a counter anion. The disclosure further discloses the corresponding chromatic polydiacetylenes and polydiacetylenes-based sensors for detecting ammonia.

The application discloses a synthesis method of deuterium-substituted olefin by using D2O as a deuterium source and a palladium membrane for catalysis, and belongs to the technical field of synthesis of deuterium-substituted olefin blocks. The application uses a three-chamber electrolytic cell separated by a palladium membrane and an ion exchange membrane as a reactor, uses the palladium membrane as a working electrode, uses a deuterium water solution as an electrolyte, electrolyzes the deuterium water by using a constant potential electrolysis method, transmits active deuterium formed to an organic reaction side using anhydrous ethanol or cyclohexane as an organic solvent, and then synthesizes deuterium-substituted olefin compounds by using a palladium membrane modified by sodium benzene thiol for catalyzing reduction and deuterization of acetylene compounds with high selectivity, so as to further synthesize corresponding deuterium-substituted drugs. The application provides a green, efficient, high-universality and low-cost amplification synthesis method for synthesizing deuterium-substituted olefin blocks containing easily-reduced and easily-hydrolyzed functional groups, and has a wide application prospect.

The present invention provides energy-sensitive adducts of an acetylenic compound having at least 25 carbon atoms with at least one substance, compositions containing the adducts, and industrial uses thereof, such as dosimetry. The adducts and compositions are sensitive to energy arising from radiation sources such as ionizing radiation, electromagnetic radiation, or heat. The X-ray structure of a salt of n-butanoic acid and morpholine shows two distinct hydrogen-bonding interactions.