13 results about "Acetylene compounds" patented technology

The invention provides radiation sensitive compositions and substrates coated with radiation sensitive compositions wherein the composition comprises a combination of metals and / or metalloid compounds, a functionalized or unfunctionalized acetylenic compound, and other optional ingredients such as amelioration agents. The invention further provides radiation sensitive devices for detection or measurement of radiation comprising substrates coated with these radiation sensitive compositions. The radiation sensitive compositions and devices have applications in dentistry, non-destructive testing, oncology, radiology, and radiotherapy, among others.

This specification provides novel acetylene compound derivatives, compositions containing such compounds, methods for producing the sames, and uses thereof. The acetylene compound derivatives are compounds of the following chemical formula (I), or their tautomers, stereoisomers, prodrugs, crystalline forms, isotopically labeled forms, pharmaceutically acceptable salts, hydrates, or solvates. The compounds and compositions of the present invention can be used in the treatment of polθ-mediated diseases or disorders, particularly cancer. JPEG2026522774000373.jpg51149

The invention belongs to the technical field of organic conjugated compounds, and particularly relates to an amidinourea-containing water-soluble arylacetylene illuminant and a preparation method and application thereof.The preparation method of the amidinourea-containing water-soluble arylacetylene illuminant comprises the following steps that (1) in the nitrogen atmosphere, an amidinourea-containing water-soluble arylacetylene illuminant is obtained; the method comprises the following steps: reacting a guanidyl monomer, an alkyne compound, a catalyst and a mixed solvent to obtain a reaction solution; (2) extracting the reaction liquid, drying an organic phase, performing rotary evaporation under reduced pressure to obtain a crude product, and separating and purifying the crude product to obtain an amidinourea-based aromatic acetylene compound; and (3) mixing the amidinourea-based aromatic acetylene compound with dichloromethane, adding trifluoroacetic acid, stirring, carrying out reduced pressure rotary evaporation, washing with an organic solvent, and drying to obtain the amidinourea-containing water-soluble aromatic acetylene illuminant. The water-soluble arylacetylene illuminant containing the amidinourea group is excellent in activity, good in water solubility, stable in chemical property, high in sensitivity and high in selectivity.

The application belongs to the technical field of organic synthesis, and discloses a method for synthesizing 2,3,6-triphenylpyridine compounds. The Pd / ETS-10 catalyst is prepared first, and then benzyl acetylene compounds and benzylamine compounds are used as substrates to realize the oxidative coupling-cycloaddition reaction of terminal acetylene and benzylamine under the action of the Pd / ETS-10 catalyst in an oxygen atmosphere, so as to synthesize the triphenylpyridine compounds by one-pot method. The synthesis method has high atom economy, the catalyst can be recycled for multiple times, and has good stability and high economic value.

The application belongs to the technical field of organic conjugated compounds, and particularly relates to a water-soluble arylene-acetylene luminophore containing amidine urea groups, a preparation method and application thereof. The preparation method of the water-soluble arylene-acetylene luminophore containing amidine urea groups comprises the following steps: (1) under a nitrogen atmosphere, reacting guanidino monomers, acetylenic compounds, a catalyst and a mixed solvent to obtain a reaction solution; (2) extracting the reaction solution, drying an organic phase, and performing rotary evaporation under reduced pressure to obtain a crude product, and then separating and purifying the crude product to obtain an amidine urea group arylene-acetylene compound; (3) mixing the amidine urea group arylene-acetylene compound with dichloromethane, adding trifluoroacetic acid, stirring, performing rotary evaporation under reduced pressure, washing with an organic solvent, and drying to obtain the water-soluble arylene-acetylene luminophore containing amidine urea groups. The water-soluble arylene-acetylene luminophore containing amidine urea groups obtained by the application has excellent activity, good water solubility, stable chemical properties, high sensitivity and strong selectivity.

An aminochalcone-diacetylene compound of Formula 1A:wherein R1 and R2 are independently selected from H and C1-C3 alkyl, A denotes a linkage connecting the chalcone and diacetylene units, m and n are independently integers in the range of 2 to 18, and the corresponding protonated form / ammonium salt of Formula 1B:wherein X is a counter anion. The disclosure further discloses the corresponding chromatic polydiacetylenes and polydiacetylenes-based sensors for detecting ammonia.

To provide: a thermally conductive addition-curable silicone composition that has good storage stability at 25°C and that requires only a short time for the storage modulus G' to exceed the loss modulus G'' when heated and cured; and a method for producing the same.SOLUTION: A thermally conductive addition-curable silicone composition contains (A) an organopolysiloxane having at least one aliphatic unsaturated hydrocarbon group per molecule and having a kinematic viscosity at 25°C of 60-100,000 mm2 / s, (B) a thermally conductive filler containing amorphous aluminum nitride powder and amorphous zinc oxide powder, (C) an organohydrogenpolysiloxane having two or more hydrogen atoms bonded to silicon atoms per molecule, (D) a platinum group metal catalyst, (E) an organopolysiloxane represented by the specified general formula (1), and (F) one or more addition curing reaction control agents selected from the group consisting of acetylene compounds, nitrogen compounds, organophosphorus compounds, oxime compounds and organic chloro compounds.SELECTED DRAWING: None

The application discloses a synthesis method of deuterium-substituted olefin by using D2O as a deuterium source and a palladium membrane for catalysis, and belongs to the technical field of synthesis of deuterium-substituted olefin blocks. The application uses a three-chamber electrolytic cell separated by a palladium membrane and an ion exchange membrane as a reactor, uses the palladium membrane as a working electrode, uses a deuterium water solution as an electrolyte, electrolyzes the deuterium water by using a constant potential electrolysis method, transmits active deuterium formed to an organic reaction side using anhydrous ethanol or cyclohexane as an organic solvent, and then synthesizes deuterium-substituted olefin compounds by using a palladium membrane modified by sodium benzene thiol for catalyzing reduction and deuterization of acetylene compounds with high selectivity, so as to further synthesize corresponding deuterium-substituted drugs. The application provides a green, efficient, high-universality and low-cost amplification synthesis method for synthesizing deuterium-substituted olefin blocks containing easily-reduced and easily-hydrolyzed functional groups, and has a wide application prospect.

The present invention provides energy-sensitive adducts of an acetylenic compound having at least 25 carbon atoms with at least one substance, compositions containing the adducts, and industrial uses thereof, such as dosimetry. The adducts and compositions are sensitive to energy arising from radiation sources such as ionizing radiation, electromagnetic radiation, or heat. The X-ray structure of a salt of n-butanoic acid and morpholine shows two distinct hydrogen-bonding interactions.

The present invention is a thermally conductive addition-curable silicone composition characterized by containing (A) an organopolysiloxane having at least one aliphatic unsaturated hydrocarbon group per molecule and having a kinematic viscosity at 25°C of 60-100,000 mm2 / s, (B) a thermally conductive filler containing amorphous aluminum nitride powder and amorphous zinc oxide powder, (C) an organohydrogenpolysiloxane having two or more hydrogen atoms bonded to silicon atoms per molecule, (D) a platinum group metal catalyst, (E) an organopolysiloxane represented by general formula (1), and (F) one or more addition curing reaction control agents selected from the group consisting of acetylene compounds, nitrogen compounds, organophosphorus compounds, oxime compounds, and organic chloro compounds. Provided thereby are: a thermally conductive addition-curable silicone composition that requires only a short time for the storage modulus G' to exceed the loss modulus G'' when heated and cured and has good storage stability at 25° C; and a method for producing the thermally conductive addition-curable silicone composition.

The present invention is a thermally conductive addition-curable silicone composition comprising: (A) an organopolysiloxane having at least one alkynyl group in one molecule and having a kinetic viscosity at 25°C of 60-100,000 mm2 / s; (B) at least one thermally conductive filler selected from the group consisting of metals, metal oxides, metal hydroxides, metal nitrides, metal carbides, and allotropes of carbon; (C) an organohydrogenpolysiloxane having, in one molecule, two or more hydrogen atoms each bonded to a silicon atom; (D) a platinum group metal catalyst; and (E) one or more addition curing reaction control agents selected from the group consisting of acetylene compounds, nitrogen compounds, organophosphorus compounds, oxime compounds, and organochlorine compounds. Thereby provided is a thermally conductive addition-curable silicone composition which provides a cured product having a low storage elastic modulus G' and a high elongation when the composition is heated and cured.

The application discloses a preparation method of an indeno[1,2-b]indol-10(5H)-one compound, which comprises the following steps: adding a palladium catalyst, a ligand, a base, an additive, a carbonyl source, a 2-amino phenyl acetylene compound and an iodine element into an organic solvent, and reacting at 100 DEG C for 20 hours; and after the reaction is completed, post-treatment is performed to obtain the indeno[1,2-b]indol-10(5H)-one compound. The preparation method is simple in operation, low in cost of starting materials, high in reaction efficiency, good in substrate compatibility, efficient and fast in one-step synthesis of the indeno[1,2-b]indol-10(5H)-one compound, and convenient to operate, and the practicability of the method is widened.

The present invention aims to provide a new method for the copper-catalyzed synthesis of organic antimony acetylene compounds and their application in the preparation of triazoles. The method is characterized in that the organic antimony acetylene compounds are prepared by copper-catalyzed cross-coupling of organic antimony chloride compounds with aromatic terminal alkynes and alkyl terminal alkynes, and the organic antimony acetylene compounds are applied to copper-catalyzed three-component cross-coupling to prepare triazole compounds.