The invention discloses two-
photon fluorescent dye based on phenyl-substituted
boron-dipyrromethene and diphenyl indenofluorene; the two-
photon fluorescent dye has a structural general formula shown in the description, wherein R is C1-C18
alkyl; the synthetic steps include: using 2,4-dimethylpyrrole and
benzaldehyde as raw materials to generate 5-phenyl-substituted and 2,6-
iodide boron-dipyrromethene; reducing indenofluorene dione, alkylating, brominating, carrying out Pd(0) catalytic
amination, carrying out Pd(0) and CuI catalyzed Sonogashira cross-
coupling reaction, and removing
trimethylsilyl to generate
diphenylamine-indenofluorene-ethynyl compound; enabling the 2,6-
iodide boron-dipyrromethene to react with the
diphenylamine-indenofluorene-ethynyl compound to obtain the two-
photon fluorescent dye; the two-photon fluorescent dye has high two-photon
fluorescence, maximum two-photon absorption section in
toluene reaches 776 GM, fluorescent
quantum yield reaches 0.46, and a new idea to synthesize and apply two-photon fluorescent dyes based on boron-dipyrromethene is provided.