37 results about "AutoAnalyzer" patented technology

An automatic analyzer has a plurality of analytical units to which analysis items are allocated. When necessity of execution of calibration or accuracy management occurs, a display block relating to an occurrence cause on a state inspection screen flickers. When a receiving button corresponding to the flickering display block is instructed, the related analysis item name and analytical unit name are displayed in the display area and calibration or accuracy management is executed.

There is provided a highly reliable autoanalyzer less liable to sample and reagent carry-over and capable of preventing contamination and precisely pipetting samples and reagents. Using a sample pipetting nozzle 27 having water-repellent surfaces, a sample is pipetted from a sample cell 25 to a reaction cell 4 having a hydrophilic bottom face.

A method for fractional measurement of small, dense LDL, which is adaptable for an autoanalyzer, and a reagent for measurement, are provided, making it possible to conduct rapid and convenient analysis with good sensitivity without pretreatment of a specimen. The method for quantitatively determining small, dense LDL cholesterol in a sample comprises the steps of:

(1) eliminating cholesterol in LDL other than small, dense LDL in the presence of phospholipase; and

(2) quantitatively determining cholesterol in lipoproteins remaining in step (1) above.

Provided is an autoanalyzer which is equipped with a reagent disc having a plurality of reagent containers mounted thereon and performs qualitative/quantitative analysis of a living body sample such as blood or urine, wherein measurement error of the liquid level of reagent caused by swinging of the liquid surface incident to rotary operation of the reagent disc is reduced. Assuming a predetermined cycle time is one unit, the reagent disc having the reagent containers mounted thereon is transported to a liquid level detection position using two units or more when the liquid level of the reagent is measured.

A specimen is sequentially sampled by a probe, and at least one of the number of times of cleaning and a cleaning time when cleaning the probe is changed based on at least one of the number of times of sampling of the specimen by the probe and a sampling amount of the specimen.

An autoanalyzer includes a measurement unit which measures a reaction liquid produced by an interaction between a reagent and an examined sample contained in a reaction container, a sample probe which sucks the examined sample from a sample container and discharges the examined sample to the reaction container, a probe elevating arm which elevates the sample probe with respect to the sample container, and a control unit which controls the probe elevating arm so that a speed at which the sample probe enters a liquid surface of the examined sample to perform an n-th suction operation (n≧2) of the examined sample is slower than a speed at which the sample probe enters the liquid surface of the examined sample to perform a first suction operation of the examined sample.

To provide an autoanalyzer for analyzing a sugar chain contained in a biological sample, in particular, serum. Namely, it is intended to provide a method of analyzing a sugar chain in a sample, which comprises the following steps: A) the sugar chain-releasing step of releasing the sugar chain in the sample; B) the detection sample-preparing step of preparing the released sugar chain for detection; and, in the case of conducting mass spectrometry using a plate, C) the step of forming a plate for the mass spectrometry having the captured sugar chain dotted thereon which comprises the step of providing the tagged sugar chain sample solution obtained in the step B) on a collection plate; and, if required, the step of conducting an operation in a solid phase support-enclosed plate to form the plate for mass spectrometry; and D) the step of analyzing the sugar chain to be assayed.

A liquid exchange method of exchanging liquids present around a magnetic substance is provided. The method serves to prevent a remaining liquid from transferring to a next step and a loss of the magnetic substance. Even when the liquid exchange method is applied to an autoanalyzer, the device structure will not be complicated. A vessel 11 in which a liquid 16 containing a magnetic substance 15, a vessel 12 containing a liquid 17, a magnetic substance move-mediating member 13 and also a magnet 18 are prepared. The magnet 18 is disposed at the exterior of the vessel 11, and the magnet 18 is moved to move the magnetic substance 15 on the inner wall face of the vessel 11 in order to take out the magnetic substance 15 from the magnetic substance containing liquid 16, to move the magnetic substance 15 from the inner wall face of the vessel 11 to the surface of the magnetic substance move-mediating member 13, and to move to the inner wall face of the other vessel 12 via the magnetic substance move-mediating member 13 so as to introduce the magnetic substance 15 into the liquid 17 in the vessel 12, thereby exchanging the liquids present around the magnetic substance 15.

Provided is a composite multi-reagent vessel for an autoanalyzer, which prevents incorrectly combining a plurality of reagents including a standard or a control, and eliminates the work for combining reagents for analysis. A plurality of containers are each capable of standing on their own and are connected together each with an opening portion at the top and each being detachable and capable of standing as the connected reagent containers, thereby forming the composite multi-reagent vessel for the autoanalyzer to have reagents for analyzing the same analytical item therein, and a small container to have a reagent therein that is held on a step or a concave portion formed at a shoulder portion of any of the connected reagent containers.

A reagent for fractional measurement of small, dense LDLs without pretreatment of a specimen, which is adaptable to a rapid and convenient autoanalyzer, is provided. A method for quantitatively determining cholesterol in small, dense LDLs in a sample is further provided, comprising: a first step of eliminating lipoproteins other than small, dense LDLs in a sample in the presence of cholesterol esterase and 0.05 g/L to 1.0 g/L of a surfactant that acts on the lipoproteins other than small, dense LDLs; and a second step of quantitatively determining cholesterol in small, dense LDLs that remain after the first step.

The invention discloses a high-concentration glucose removal method for determining serum 1,5 anhydro-D-glucitol based on a pyranose oxidase method, which comprises the following steps: preparing a 2-morpholinoethanesulfonic acid (MES) buffer solution having a pH value of 6.0-9.0, wherein the MES buffer solution contains a certain amount of glucokinase (GK), glucose-6-phosphate dehydrogenase (G6PD), nicotinamide adenine dinucleotide phosphate (NADP), pyruvate kinase (PK), phosphoenolpyruvate (PEP) and adenosine triphosphate (ATP); and adding into a serum sample containing glucose (Glu), and reacting at 20-50 DEG C for 3-5 minutes, wherein the GK converts the Glu into glucose-6-phosphoric acid (G6P) in the presence of the ATP, and adenosine diphosphate (ADP) is generated at the same time; the G6P is further converted into glucose-6-phosphate lactone (G6PL) by the G6PD in the presence of the NADP+; and the ADP generated in the reaction is converted into ATP again under the action of thePK in the presence of the PEP. The glucose removal agent prepared by the method can be stably stored at 2-8 DEG C for 14 months, and can be used for a clinical biochemical autoanalyzer extensively used at present.

In an autoanalyzer for analyzing a specimen such as urine and blood, protecting a measurement value of analysis from influence of a dispensing nozzle repeatedly used. For this purpose, a phosphonic acid derivative or a phosphoric acid derivative is chemically adsorbed on the surface of the dispensing nozzle. In this manner, a molecular layer for suppressing adsorption of biopolymers or adhesion of a specimen per se is formed on the nozzle surface to prevent accuracy of analysis from being influenced.

The invention relates to the technical field of wastewater treatment and particularly relates to a system for intelligently controlling dosing amount in heavy metal wastewater treatment. The system includes, in a successively connected manner, a first water quality auto-analysis device, a first flow sensor, a reaction tank, a second water quality auto-analysis device, a first electric valve and asecond flow sensor, and also includes a backflow bypass connected between the second water quality auto-analysis device and the first electric valve. The backflow bypass is successively provided witha second electric valve and a third flow sensor. The system further includes a reagent metering pump connected to the reaction tank, and an intelligent control system respectively connected to the first water quality auto-analysis device, the second water quality auto-analysis device, the flow sensor and the reagent metering pump through signals. During control of dosing amount, the system can change the dose by fluctuation of heavy metal content in the wastewater, so that on the basis of guaranteeing the effluent quality, waste of the reagent is reduced, and quantity of sludge is reduced, misjudgment rate by manual work is reduced, and high efficiency and manpower saving are achieved.

In an autoanalyzer for analyzing samples, such as urine and blood, analytical and measured values are prevented from being affected by carry-over caused by the repeated use of a pipetting nozzle. A molecular layer for inhibiting the adsorption of biological polymers is formed by coating surfaces of the pipetting nozzle with a polyethylene glycol derivative chemisorbed thereto, thereby reducing carry-over caused by the pipetting nozzle.

The invention belongs to the field of environmental monitoring and particularly relates to a water integrative biotoxicity online monitoring autoanalyzer. The water integrative biotoxicity online monitoring autoanalyzer is provided with a unique photoelectric detection unit. The water integrative biotoxicity online monitoring autoanalyzer is high in integration level small in structure convenientto move, suitable for field test and high in degree of automation, is capable of realizing online real-time monitoring without manual watching, and is high in detection sensitivity and good in accuracy.