Urban comprehensive intelligent information inquiry system and inquiry method are provided, which relates to the technical field of urban comprehensive intelligent information inquiry. The invention is intended to resolve the problems of no pertinence, inaccuracy, low efficiency, waste of time, resources, labor and money in existing website, integral inquiry machine and tolled voice telephone in inquiring urban comprehensive information. The invention is characterized in that: a touch screen LCD (1), a LCD drive circuit (2), a touch screen control circuit (3), a 232 serial communication circuit (5) and an external memory unit (6) are connected to a singlechip circuit (4). The operational procedure of the invention is: read the parameter of coordinate in real time; select the language for operation interface; select and operate the inquiry type. Therefore, the invention is able to carry out real-time inquiry of urban comprehensive information, such as the inquiry of bus route, hotel, bank, guesthouse, scenic spots, department stores, hospitals, schools, enterprise, and governmental agencies.