The invention provides a harvesting method of cortex juglandis mandshuricae and a processing method of the cortex juglandis mandshuricae, and relates to a harvesting method of traditional Chinese medicines and a processing method of the traditional Chinese medicines. The harvesting method solves the problems that at present, the quality stability of the cortex juglandis mandshuricae in different batches is poor, the contents of naphthoquinone type active ingredients are very different, anticancer ingredients, namely juglone, are toxicant, only fresh juglone can be used for preparing medicines, in the processing process, the juglone is easy to damage, and the anticancer effect is poor. The harvesting method comprises the following steps: harvesting green walnut peel which is not matured after 15-20 days from the start of the hottest day of the year. The processing method comprises the following steps: I, harvesting the green walnut peel which is not matured; and II, drying the harvested green walnut peel which is not matured at low temperature in a manner of variable temperatures. The processing method disclosed by the invention can promote the toxic ingredients, namely the juglone to be converted into the active ingredients namely the juglone so as to achieve the purposes increasing efficacy and reducing poisonousness. Therefore, according to antitumor medicines prepared from the cortex juglandis mandshuricae processed by the method disclosed by the invention, the effect of tumor inhibition is greatly improved, the toxin is reduced, the using safety is high, and the medication security is ensured.