13 results about "Low weight birth" patented technology

The invention discloses a method for establishing a mutual-aid human milk library in a hospital for infants with extremely low birth weight. The method comprises the following steps of: recruiting and screening donators with relatively high breast milk yield in the hospital; performing breast milk sterile collection on the selected qualified donors; putting the collected breast milk into a human milk library for centralized storage and management; taking the collected breast milk so as to supply breast milk to the infant lacking breast milk in the hospital; and when the breast milk supply amount of the infant parent and mother is greater than the feeding amount of the doctor's advice, recruiting and screening the infant parent and mother so as to enable the infant parent and mother to become a qualified donator. The beneficial effects are that the in-hospital mutual-aid human milk library of the extremely-low birth weight infants is established according to the method, the residual breast milk of the mother of the extremely-low birth weight infant after being discharged from the hospital can be donated to other extremely-low birth weight infants, the use of the donated milk of the premature infants with similar fetal age and lactation period is more beneficial to the growth and development of the extremely-low birth weight infants, and the operation cost can be reduced at the same time; the stable donation amount is of great significance to the healthy development of children with extremely low birth weight and the long-term stable operation of a human milk library.

The invention discloses a jaundice detection device for child treatment, and relates to the technical field of jaundice treatment and detection. The system comprises a treatment bed, the treatment bed is provided with an image acquisition unit, a data transmission unit, a phototherapy unit, an intelligent control unit and an output unit, and the intelligent control unit comprises a data preprocessing module, a feature extraction module, a jaundice diagnosis module and a treatment suggestion module. The mode of combining computer vision, intelligent control and the phototherapy technology is adopted, intelligent diagnosis and treatment of neonatal jaundice are achieved, and the system has the advantages of being easy to operate, high in precision, safe and reliable; the blue light which reduces the oxidative pressure of the newborns can reduce the concentration of bilirubin in blood, the oxidative pressure of the newborns can be reduced, the concentration of bilirubin in blood can be reduced, and the jaundice treatment effect on the newborns (extremely low birth weight) with the birth weight less than 1500 g is especially achieved.

The invention belongs to the technical field of animal husbandry breeding, and particularly relates to a breeding method for low-birth-weight Hu lambs. The invention relates to a breeding method of low birth weight Hu sheep lambs, which specifically comprises the following steps: lambs with birth weight lower than 1.5 standard deviation of a total average value eat breast milk in time after birth and live together with ewes; when the lambs are 5 days old, starter feed is added, sodium butyrate is fed into the lambs, and the lambs can freely eat the starter feed; the feeding mode of sodium butyrate is as follows: 40g of sodium butyrate is dissolved in 100ml of normal saline to prepare a solution with the final concentration of 0.4 g / ml, and each lamb is fed with 0.8 ml / kg-1 ml / kg of sodium butyrate; the body weight is measured once a week, and the feeding amount of sodium butyrate is adjusted according to body weight changes; the feed is stopped after 30-35 days of feeding with sodium butyrate, and weaning is carried out. By means of the method, healthy growth of the low-birth-weight Hu lambs can be achieved, the immune function and the oxidation resistance of animal bodies are improved, and therefore the production performance is improved.

The present invention belongs to the field of molecular biotechnology and molecular marker technology, and discloses a SNP molecular marker related to pig birth weight and its application. The SNP molecular marker related to pig birth weight corresponds to the nucleic acid site at 5379864 bp on chromosome 16 of the pig reference genome Sscrofa11.1 version sequence. The base of the site is C or T and is contained in the intron of the MARCHF11 gene. The present invention also discloses the application of the SNP molecular marker related to pig birth weight in the genetic breeding of Landrace pigs, and provides a method for selecting or assisting in the selection of pigs with high / low birth weight using the SNP molecular marker and a primer for identifying the SNP site. The above method can achieve accurate prediction and efficient selection of Landrace pig birth weight, promote the cultivation of excellent breeding pigs, accelerate the population improvement process, and provide strong support for the sustainable development of the pig farming industry.

The invention discloses application of an IL1R2 gene in regulation and control of pig placenta development or improvement of pig birth weight. According to the present invention, transcriptome sequencing and whole genome methylation sequencing are performed on placenta samples of high birth weight (HBW) piglets and low birth weight (LBW) piglets in the same nest, such that the differential methylation differential expression gene IL1R2 is screened, and the methylation level of the gene in the HBW placenta is high, and the expression quantity is low; therefore, by regulating the methylation level or expression level of the IL1R2 gene, the development quality of the pig placenta can be improved, the birth weight and survival rate of piglets are further improved, and the breeding efficiency of sows and the market competitiveness of pig farms can be improved.

The invention discloses premature infant / low birth weight infant formula milk powder, a low side reaction preparation method and an evaluation analysis method, and belongs to the field of emulsion preparation. The technical problems that in the prior art, premature infant / low-birth-weight infant formula milk powder has the characteristics of high protein and high fat, and the protein-lipid co-oxidation phenomenon is prone to occurring are solved, the low-side-reaction preparation method of the premature infant / low-birth-weight infant formula milk powder is provided, and by changing homogenizing process parameters, the low-side-reaction content of the premature infant / low-birth-weight infant formula milk powder is improved. Through cooperation of sterilization and vacuum spray drying technologies, the interface protein content and emulsifying activity of the formula milk powder are improved, protein-lipid co-oxidation is reduced to the greatest extent, and the stability of the formula milk powder is enhanced; based on a quantitative structure-activity relationship (QSAR) model, the invention also provides an evaluation analysis method, which can accurately predict the influence of homogeneous process parameters and interface characteristics on oxidation stability, and provides a new method for accurate manufacturing of premature infant / low birth weight infant formula food.

A method for supporting diagnosis of intraventricular hemorrhage and early death within a week in very low birth weight infants based on deep learning includes a data collection step, a data preprocessing step, a learning step of training a prenatal prediction model, training a birth prediction model and training a postnatal prediction model, and a diagnosis step of, when a diagnosis target and diagnosis time are determined, selecting one prediction model based on the diagnosis time, analyzing medical information of the diagnosis target through the selected prediction model, and predicting and outputting the intraventricular hemorrhage diagnosis result.

The invention provides a multi-mode maternal and infant emotion interaction and physiological data fusion feedback system chair for the obstetrics department, which is specially designed for kangaroo type nursing of premature infants, low birth weight infants and sick newborns, and comprises an adjustable ergonomic chair body used for providing comfortable support; the multi-modal data acquisition module is used for acquiring infant physiological data, behavior data and environment data; the data fusion analysis module is used for carrying out standardization processing and fusion analysis on the multi-source data and evaluating the state of the baby; the self-adaptive early warning module is used for dynamically adjusting an early warning threshold value based on the individualized baseline parameters; the interactive feedback module is used for providing visual, auditory and tactile multi-channel feedback; the mother and infant interaction optimization module analyzes the interaction mode and generates personalized suggestions; the problems of insufficient comfort, lack of safety monitoring, lack of visibility and the like in traditional kangaroo type nursing are solved, the functions of multi-modal data fusion, self-adaptive early warning and personalized interaction are achieved, and the safety, comfort and effectiveness of kangaroo type nursing are remarkably improved.

The present disclosure relates to the treatment of disorders of gastrointestinal (also referred to herein as GI) tract regeneration and / or maturation, in particular in infants, such as preterm infants (also referred to herein as neonates), pregnant low-weight young children, and / or young children born after preeclampsia, by administering a therapeutically effective amount of IGF-1, in particular as a complex with IGFBP, such as IGFBP-3. The treatment may also be used in other patient populations, including adult populations with GI tract conditions / disorders / diseases / and / or infections.

This product is an undergarment for low-birth-weight infants with extremely sensitive skin. It has a double-layered structure with a skin-friendly material on the inside and a material with a certain degree of strength on the outside. The edges are folded outwards and reinforced with fabric sewn only on the outside, and the front and back are formed into a tubular shape from a single piece of fabric, so that the folded edges and seams of the entire undergarment do not directly irritate the skin.

A fluid delivery and airway management device including a tubular member dimensioned for introducing a fluid into a trachea of a mammal, the tubular member having a proximal portion, a distal portion, and a middle portion between the proximal portion and the distal portion. The tubular member is dimensioned for positioning of the proximal portion in an oral cavity of a mammal, the middle portion in an oropharynx of the mammal and the distal portion in an esophagus of the mammal. An inflatable oral cavity balloon is positioned at the proximal portion and dimensioned to occlude the oral cavity. An inflatable esophageal balloon is positioned at the distal portion and dimensioned to occlude the esophagus. Apertures may be formed within the middle portion such that a fluid introduced into the tubular member is output through the apertures to a trachea.

Disclosed is a method for monitoring and evaluation of bowel health in premature newborns. The method involves collecting stool / fecal samples from premature newborns / babies and processing the sample using microbiomics, automated cell counting, flowcytometry, and RT PCR analysis using specific gene signature or RNA transcriptomics analysis to determine risk of necrotizing enterocolitis. The method allows evaluation and tracking of gut health without needing to draw a blood test and is a non-invasive method. The method diagnoses and prevents bowel inflammation, infection and necrotizing enterocolitis (NEC) that facilitates initiation of prompt therapy to limit morbidity and mortality in premature babies. The method facilitates early management of signs of NEC thereby helping to save lives of premature babies and infants having low birth weight.

The invention discloses a nutritional composition. The nutritional composition comprises animal protein, vegetable protein and prebiotics, in the nutritional composition, the mass ratio of the animal protein to the vegetable protein to the prebiotics is 1: (3-6): (0.4-0.8). The invention also discloses application of the nutritional composition in maintaining stable diversity of intestinal flora during pregnancy and improving the birth outcome of newborns. According to the nutritional composition provided by the invention, by optimizing the ratio of the resistant dextrin to the protein and reasonably adjusting the ratio of the plant protein to the animal protein, the alpha diversity stability of intestinal flora in each stage (including early pregnancy, middle pregnancy and late pregnancy) of pregnancy can be effectively maintained; moreover, the growth retardation of the newborns can be reduced, the premature birth rate and the low birth weight incidence rate are reduced, and the birth outcome of the newborns is remarkably improved.