The invention discloses a model-driven open architecture of a UAV ground station, which is oriented to different UAV system command and control platforms, meets the needs of equipment system development, and clearly defines the systems, subsystems and service components within the framework. The data model divides the functional domain and platform domain for different applications, and establishes the drone command and control standardization service based on the platform-independent model to realize the separation of the application and the platform. At the same time, combined with the platform domain related services, middleware selection and software architecture, the model-driven process is used to complete the transformation of the platform-independent model to the platform-related model, support the development requirements of the subsequent application APP code generation, and the development and design and operation platform of the ground accusation system. Separation, the decoupling of core application software and underlying hardware are achieved, supporting the rapid migration, management and deployment of generalized application software.