The invention discloses an indigowoad leaf/clove leaf non-tobacco cigarette and a preparation method thereof, belonging to the technical field of cigarettes to solve the problems that indigowoad leaf and clove leaf resources are wasted, and a medicine cigarette is poor in taste and mouthfeel, causes damages to health, is bad in mildew resistance, unstable in product smell taste and shelf life, and the like in the prior art. The preparation method of the indigowoad leaf/clove leaf non-tobacco cigarette comprises the following steps: firstly, soaking indigowoad leaves and clove leaves in hydrogen-rich normal saline of which the hydrogen concentration is 0.3-0.8mmol/L respectively; secondly, heating the indigowoad leaves and clove leaves after soaking respectively in a segmented mode, then cooling the leaves to a room temperature, performing microwave drying, performing moisture regaining on the dried indigowoad leaves and clove leaves, and cutting the leaves into cut tobaccos; and finally, taking the indigowoad leaf cut tobaccos and the clove leaf cut tobaccos in a mass ratio of 1:1, adding an anti-mildew agent, mixing uniformly, and performing cigarette forming, thereby obtaining the indigowoad leaf/clove leaf non-tobacco cigarette. The indigowoad leaf/clove leaf non-tobacco cigarette reduces resource waste, is good in smell, mouthfeel and mildew resistance, does not influence the health of a smoker, and has functions of resisting fatigue and improving immunity.