179 results about "Urine specimen" patented technology

The invention relates to a kit for detecting neutrophil gelatinase-associated lipocalin content based on chemiluminescence immunoassay. According to the invention, by employing a double-antibody sandwich immunization analysis method, a chemiluminescence magnetic microspheres immunization technology is used, anti-NGAL antibody-coated magnetic microspheres for specifically combining with NGAL antigen of a standard substance / sample in a reaction cup, then are reacted to another strain anti-NGAL antibody labelled with acridine salt to form an immunization compound, through an acid-base chemical reaction of a pre-Trigger and a Trigger, relative light unit (RLU / s) of the chemiluminescence reaction can be measured; the NGAL antigen content in the sample is in direct proportion to the relative light unit (RLU / s) measured by an optical system, determination of NGAL content in an urine specimen can be determined through standard curve fitting; and the method has the obvious advantages of high sensitivity, strong specificity, good stability, simple operation and low cost.

A device, method and kit for collection of a urine specimen from an animal includes a cup to receive and hold the urine specimen, a lid to close cup after collection of the specimen, and a holder with a generally upright center extension member, a handle connected at the upper end of the extension member, and a cup holder extending forwardly from the lower end of the extension member and having an opening slidably receiving the cup for manual positioning of the cup under the animal from which the urine specimen is to be collected.

The present invention relates to a urine specimen capture device comprising a capture bowl for collecting a urine specimen, a mounting frame for supporting the capture bowl within a toilet bowl, and an analytic device connected to the capture bowl to analyze a property of the urine specimen in the capture bowl.

The invention discloses a disposable closed middle urine retention device, which comprises a funnel, the funnel is fixedly connected with a pipeline through a threaded interface, a two-way valve is installed on the pipeline, and the pipeline is connected with a retractable bellows through a screw thread. It is fixedly connected, the flexible bellows communicates with the urine storage container, and one side of the pipeline is connected with an anti-blocking gas filling device. The present invention can conveniently collect the mid-section urine of patients with urinary incontinence, reducing cumbersome operation steps; it can also ensure the airtightness of the container during the urine collection process, so as to reduce the possibility of urine specimens being polluted and avoid secondary contamination. Pollution, to ensure the authenticity of the test results, to eliminate the original problem of not being easy to hold the container, and to avoid contamination of the bed sheets.

The present invention relates to a urine specimen capture device comprising a capture bowl to capture a urine specimen, a mounting frame connected to the capture bowl to support the capture bowl within a toilet bowl and one or more flush water capture flange for capturing flush water emitted from a toilet bowl rim during a toilet flush cycle and diverting the flush water to the capture bowl to rinse the capture bowl of the urine specimen.

The method for reminding an individual to collect a urine specimen includes providing at least one reminder label such that the individual will discover the label in the course of preparing to urinate, thereby serving as a reminder to collect the urine specimen, attaching the label to a location where the label will be encountered by the individual when preparing to urinate, discovering the label when preparing to urinate, reminding the individual to collect the urine specimen when the individual discovers the label, and collecting the urine specimen in a collection container. Reminder labels include, but are not limited to, pads, clips, guards, temporary tattoos for use on skin, adhesive paper labels, adhesive plastic labels, adhesive foil labels, and textile labels.

An objective is to provide a method and an apparatus for accurately extracting a region of an object particle from a urine particle image obtained by taking an image of urine particles in a urine specimen having varying properties. First, a first object region is extracted using one or more of an R image, a G image, and a B image of a urine particle image taken by an image input optical system configured to input particle images. Then, a density distribution and a size of the first object region of one or more of the R image, the G image, and the B image are calculated. Based on these feature parameters, the first object region is classified into a predetermined number of groups. A second object region is extracted from a local region including the first object region, by using one or more of the R image, the G image, and the B image, depending on each of the groups. This configuration allows stable region segmentation for each particle image even for a urine specimen in which urine particles having different sizes and tones coexist.

A method and a device for sampling and storing a urine specimen capable of recovering a sampled urine specimen to a recovery container (5) through a filter (2) by the sucking pressure of the decompressed and enclosed recovery container (5); the device for sampling and storing the urine specimen, comprising a filter holder (3) having a space for storing the filter (2) for filtrating the urine specimen, the filter (2) stored therein, and the recovery container (5) decompressed and enclosed by a plug body (4), wherein hollow tubes (6) with a sharp tip communicating with a space (S) having the filter (2) stored therein is installed in the filter holder (3) on a specimen delivery side to the recovery container (5).

The present invention discloses a bladder cancer biomarker and a test method using the same. The biomarker contains at least one of the mentioned 69 compounds, such as apolipoprotein A1 (APOA1), apolipoprotein A2 (APOA2), peroxiredoxin 2 (PRDX2), heparin cofactor 2 precursor (HCII), and serum amyloid A-4 protein (SAA4), which exist in the urine specimen of a testee. The expression intensity of the biomarker can facilitate diagnosis of bladder cancer and evaluation of aggressiveness and malignancy of bladder cancer. Thereby, the physician can arrange an optimized treatment to achieve the best therapeutic effect.

The invention provides a method for analyzing urine exosome miRNA, comprising: collecting a urine sample, extracting exosomes and their total RNA, establishing a cDNA library, performing Illumina sequencing, and processing and annotating the sequencing results to obtain expression information of sample miRNA expression quantity; urine sample exosome miRNA is analyzed by high-throughput sequencing technology to acquire expression information of miRNA; a database for IgA nephrotic patient and a healthy control patient is established, differentially expressed miRNA is deeply studied through target gene function prediction, the deep study on the differentially expressed miRNA helps further illustrate the pathogenesis of IgA nephropathy, and novel method and theoretical basis is provided for the diagnosis of IgA nephropathy. The method is reasonable and feasible in design, a noninvasive precise differential expression miRNA method can be effectively established, and novel ideas are provided for clinical diagnosis and treatment.

The invention discloses a method for detection of microRNAs in excreta (sputum, faeces and urine) as a biomarker for early screening and diagnosing lung cancer, colorectal cancer and bladder cancer. The method comprises: (1) screening abnormal expression microRNAs existed in tissues of the lung cancer, the colorectal cancer and the bladder cancer; (2) by using resection tumor samples from patients of the lung cancer, the colorectal cancer and the bladder cancer, verifying the screened microRNAs in the tumor tissues; and (3) detecting expressions of the microRNAs in samples of sputum, faeces and urine from the patients of the lung cancer, the colorectal cancer and the bladder cancer, analyzing correlation with expression in the tissues, and confirming the microRNAs for early screening and diagnosis. The method is substantially characterized in that the microRNAs in the excreta is taken as the biomarker for early screening and diagnosing the cancers, and the method helps to realize noninvasive screening for the cancer patients and possesses a wide application scope.

The invention discloses a complete antigen for detecting tetrahydrocannabinol and preparing an antibody. The invention also discloses an anti-tetrahydrocannabinol monoclonal antibody prepared by the complete antigen and a tetrahydrocannabinol monoclonal antibody immunity detection plate through a collaurum tag for detecting the tetrahydrocannabinol in medicine, a urine specimen or other human specimens. Compared with HPLC and other methods, the detection plate is simple, portable and easy to carry, can carry out field detection and does not need expensive equipment. When the detection plate is used to detect the tetrahydrocannabinol, the whole test can be completed within 1.5 minutes; the detecting sensitivity can reach 0.5ng; and the detection plate has no crossed reaction with more than 60 kinds of common medicaments, drugs and internal metabolins of the tetrahydrocannabinol.

The present invention relates to a urine specimen capture device comprising a narrow slit disposed on a surface exposed to urine that retains a portion of the urine specimen.

A system for collecting urine specimens from pet or animal comprising an elongated tray section having at one end a collection chamber for collecting a predetermined volume of urine in fluid communication with an open section of said tray to receive a stream of urine from the pet or animal, a discharge port at the opposite end of said tray and a specimen vial removably mounted to the discharge end of said tray whereby when an animal is urinating, the device is positioned under the stream with the collection chamber end downwardly inclined so that a sufficient quantity flows into the collection chamber to predetermined level and then tilting the device in a reverse direction so the collected sample flows into the specimen vial and is sealed.

The invention discloses an intelligent collector for midstream urine of an infant. The intelligent collector is characterized in that a urine receiving device, a urinary catheter and branch catheters are sequentially connected, wherein the branch catheters comprise a first catheter and a second catheter; the first catheter is connected with a urine collecting bag; the second catheter is connected with a urine cup; a first infrared transmitter and a first infrared receiver which are mutually symmetric are arranged on the outer side wall of the urinary catheter; an electromagnetic valve for switching the catheters is arranged on the branch catheters; a second infrared transmitter and a second infrared receiver which are mutually symmetric are arranged on the outer side wall of the urine cup mouth; the first infrared receiver, the second infrared receiver and the electromagnetic valve are respectively and electrically connected with a microprocessor. Corresponding flow speed inductions are set according to the difference of urine volumes for each time of infant patients in different age groups; a 20ml midstream urine cup is arranged for directly collecting midstream urine; the midstream urine is directly taken for testing, so that secondary pollution caused by secondary pouring is avoided; after a urine specimen is successfully retained, a urine cup sensor can transmit a signal, urine reenters a disposable urine bag, so that the interruption of the urination caused by the stimulation to the infant patients is avoided.

The invention discloses a kit based on single particle diameter for simultaneously detecting beta2-microglobulin in serum and urine specimen. The kit comprises a reagent R1, a reagent R2, a calibration product and a quality control product, wherein the reagent R2 consists of a streptavidin marked latex-biotin marked rabbit anti-human beta2-microglobulin polyclonal antibody and reagent R2 buffer liquid. The kit has the advantages that the reagent sensitivity is improved; the measuring range is greatly increased; the beta2-microglobulin in the blood and urine specimen can be simultaneously detected; meanwhile, most biochemical testing equipment in the market can be compatible; the kit can directly enter the market.

A urine specimen collection device that aids in positioning a standard urine specimen cup in a urine flow path to avoid inadvertent contact between the user's hands and the urine being collected. A standard specimen collection cup is insertable through an aperture disposed in a cup holder portion of the device. The aperture is preferably expandable from a first size to a larger second size when a specimen cup is inserted and is preferably configured to support the cup in a position where around 50% or more of the height of the cup is disposed on an underside of the cup holder body. The cup holder end of the device may bend at an angle between about 120° and 170° relative to a handle end of the device when a specimen cup is inserted through the aperture. Optional handle extensions may be used to further elongate the device.

The invention discloses an automatic collection device for mid-stream urine. The device comprises a collection cup body. The collection cup body comprises an upper cup cavity and a lower cup cavity, both of which communicate with each other. The upper cup cavity communicates with the lower cup cavity through an annular sleeve pipe body. The annular sleeve pipe body comprises an outer sleeve pipe and an inner sleeve pipe. A fluid passage is formed in an annular passage between the outer sleeve pipe and the inner sleeve pipe. The upper end and the lower end of the fluid passage are respectivelyequipped with an upper check ring body and a lower metal check ring body in a matching manner. The upper check ring body and the lower metal check ring are respectively equipped with multiple throughholes. Electromagnetic attraction force of the lower metal check ring is utilized to automatically and upwardly attract an annular metal check ring of a floating block body. Therefore, the annular metal check ring can be closely connected with the lower metal check ring in an attraction manner. A through hole of the lower metal check ring is blocked so that the upper cup cavity is separated from the lower cup cavity. Therefore, mid-stream urine samples can be conveniently and automatically collected. Data accuracy of urine detection is increased. Additionally, effective and stable separation is achieved.

The invention discloses a device for collecting urine specimen. The device comprises a collect canister A and a standard centrifuge tube B. The collect canister A includes a hopper collect canister 1, a collect canister cover 2, an extensible arm 3, an extensible pipe 4, a butterfly-shape compression board 5, a spongy mass 6, a lower baffle plate 7, a sealed baffle plate 8, a dropping tube 9; the standard centrifuge tube B is a private plastic container, which has screw-thread on the inner wall of the tube opening to connect with the collect canister A.

The present invention to a protein related to carcinoma of urinary bladder and its detection method. Said invention adopts surface intensified laser desorption ionization time-of-flight mass spectra technology, combined application protein chip technology and Biomarker Patterns Software to create tree analysis mode for detecting and analyzing the specific protein related to the carcinoma of urinary bladder which has difference expression in urine sample. The sensibility of the protein related to the tested carcinoma of urinary bladder can be up to 84%, and its specificity can be up to 91%.

The invention provides a digital analyzer of a saliva or urine specimen. The digital analyzer of the saliva or urine specimen is characterized by comprising a specimen collection device and a portable specimen testing device, and the portable specimen testing device is provided with a connector used for allowing the specimen collection device to be inserted into; the specimen collection device comprises a collection sponge used for collecting saliva or urine, the collection sponge is fixed on a fixed structure, one end of a pressing rod serves as a pressing portion, the pressing portion is fixedly connected with the fixed structure, the other end of the pressing rod serves as an operation portion, one end of a detection reagent is located in the pressing portion of the pressing rod, and the other end of the detection reagent penetrates through the fixed structure and then is located in the collection sponge; the specimen collection device further comprises a specimen collection plate which is provided with a specimen collection tank, the edges of an opening of the specimen collection tank are each provided with a pressing plate, and the specimen collection plate is further provided with color-development test paper which is communicated with the specimen collection tank through a liquid path. By means of the digital analyzer of the saliva or urine specimen, whether a testee takes drugs or not can be detected any time any where, and police can enforce the law conveniently.

Embodiments of this invention disclose new second generation uric acid-sensing electrodes at least characterized by chemically bonding both uricase and the redox mediator to an electrode. The produced electrodes can be long-term stably used without losing activity. The developed electrode has been successfully applied for the analysis of uric acid (UA) in healthy human urine specimens which exhibits very good analysis accuracy and precision without too much interference. Therefore, the developed electrodes have the potential for clinical applications.

The present invention is a hand held apparatus to manually retain a urine specimen cup between the legs of a person so that a person can provide a urine specimen into the cup while precisely holding the cup beneath his or her legs so that the urine can be precisely voided into the cup.

Disclosed is a compact, foldable, sanitary urine specimen collection device. The device is intended to collect urine specimens from domestic animals, such as dogs. A telescopic pole with a handle is attached to a pivotal support member for supporting a specimen collection container.

The invention relates to a kit for detecting urine transferrin through a chemiluminescence enzyme immunoassay method, and a preparation method thereof. The kit comprises an antibody-coated plate, a urine transferrin enzyme antibody, a coating buffer solution, a blocking solution, a urine transferrin standard substance, a standard substance dilution solution, a washing solution, a sample dilution solution and a chemiluminescent substrate solution. According to the present invention, the kit can detect the UTF concentration level of human based on chemiluminescence enzyme immunoassay; the chemiluminescent substrate catalytic enzyme HRP and the anti-UTF antibody are conjugated, the obtained conjugate reacts with the sample or the antigen to form the immune complexes, the chemiluminescent substrate solution is added, the relative light unit of the chemiluminescent reaction is measured, the UTF antigen content in the standard substance / the sample is proportional to the relative light unit measured by the optical system, and through standard curve fitting, the UTF content in the urine sample is determined; and the kit of the invention has advantages of high sensitivity, strong specificity, easy operation, low cost and the like.

Disclosed is a compact, foldable, sanitary urine specimen collection device. The device is intended to collect urine specimens from domestic animals, such as dogs. A telescopic pole with a handle is attached to a pivotal support member for supporting a specimen collection container.

The invention discloses an automatic urine specimen collecting system device which comprises a urinary catheter. The top of the urinary catheter is inserted into the human bladder, a branch tube is arranged on the surface of the urinary catheter, a collecting bin is fixedly connected to the surface, close to the bottom, of the branch tube hermetically, a first shaft driven to rotate by a power mechanism limitedly rotates on the inner wall of the collecting bin, and the power mechanism is electrically connected with a microprocessor. The surface, close to the rear end, of the first shaft penetrates through the rear side of the collecting bin and is fixedly connected with a first wheel, the surface of the first wheel is sleeved with a transmission belt, and the inner wall, close to the bottom, of the collecting bin is fixedly connected with a first check valve. By adopting the matched use of the structures, the problem is solved that it is difficult to collect urine regularly due to thefact that the urine in different time periods is mixed in a urine bag in the actual use process; the problem is solved that the collection of a urine sample in each time period is also difficult to achieve, manual operation also consumes time and labor and accordingly inconvenience is brought in use.