3 results about "Serum specimen" patented technology

The present application relates to a specimen extraction solution and a specimen extraction method, and an inspection reagent using the same, the specimen extraction solution containing a component capable of inhibiting false negative reactions that cannot be completely inhibited by conventional methods when detecting antigens such as viruses, bacteria, and proteins to be detected from specimens from body fluids such as a nasal swab specimen, a nasal aspirate specimen, a nasal lavage specimen, a nasal discharge specimen, a throat swab specimen, a saliva specimen, a fecal specimen, a serum specimen, a plasma specimen, a urine specimen, and the like using an inspection reagent that utilizes antigen-antibody reactions or reactions of substances having interactions with each other. The specimen extraction solution of the inspection reagent, or a component that comes into contact with a specimen in a process before a detection reaction of a detection object or a process performed simultaneously with the detection reaction, and the like contain a water-soluble compound having a phenyl group, a benzyl group, a tolyl group, or a xylyl group in the structure, and at least a functional group including a carboxyl group or a carboxyl group methylated or ethylated atom group or a hydroxyl group bonded to the above group.

The application provides an automatic reading method and system for antibody identification results based on a vector space model, which comprises the following steps: constructing an antibody specificity vector model, mapping the antigen spectrum corresponding to each antibody specificity in an antibody identification pedigree table into an antibody specificity vector with a fixed dimension; mapping the reaction results of antibody identification of a serum sample to be tested into a to-be-tested vector through the antibody specificity vector model; calculating the similarity between the to-be-tested vector and the antibody specificity vector; and performing reading based on reading logic according to the similarity calculation results to obtain antibody identification results. The antibody identification results can be automatically read by calculating the vector similarity, the antibody identification can be realized quickly, accurately and standardly, and the work efficiency is improved significantly, and the manpower is liberated.

The application belongs to the technical field of biological medicine, discloses application of bone metastasis specific secreted protein DKK3 in early diagnosis of lung cancer bone metastasis, and specifically discloses application of a substance for detecting DKK3 in preparation of a product for diagnosing or early screening of lung cancer bone metastasis. The application discloses the relationship between secreted protein DKK3 expression and lung cancer specific bone metastasis for the first time, and verifies that secreted protein DKK3 is specifically highly expressed in serum samples of lung cancer bone metastasis patients and lung cancer bone metastasis cells, which indicates that secreted protein DKK3 can be used as a new lung cancer bone metastasis diagnostic marker, and can significantly distinguish lung cancer patients with bone metastasis from lung cancer patients with metastasis to other organs and healthy people.