The invention relates to a packaging production line used for multi-product collective packaging. The packaging production line comprises a main conveying belt, a plastic demounting support machine, a feeding conveying belt, a coding machine, a feeding manipulator, a box demounting machine, a box packing and sealing machine, a box unpacking machine, an integral code layer box filling machine, a box sealing machine and a control cabinet. The packaging production line is characterized in that the plastic demounting support machine, the feeding manipulator, the box unpacking machine and the box packing and sealing machine are sequentially connected via the main conveying belt, the coding machine is mounted on the lower portion of the feeding conveying belt, the feeding manipulator is arranged right above the main conveying belt and higher than the feeding conveying belt, and the main conveying belt, the plastic demounting support machine, the feeding conveying belt, the coding machine, the feeding manipulator, the box demounting machine, the box packing and sealing machine, the box unpacking machine, the integral code layer box filling machine and the box sealing machine are electrically connected with a control system in the control cabinet.