The invention discloses an active 3D simulation system based on virtual and live-action three dimensions, which belongs to the field of active 3D simulation systems based on virtual and live-action three dimensions, and comprises a data server, an application server, a 3D projector, a receiving card, a projection screen, 3D glasses, an infrared synchronous signal module, a 3D synchronous transmitter module and a simulation platform, the data server is connected with the application server, the application server is respectively connected with the simulation platform and the 3D projector, and the 3D projector is connected with the projection screen and the 3D glasses. Dynamic simulation and active 3D experience of natural geography, human landscapes and three-dimensional real scenes of different areas can be realized, and a user can perceive and experience environment characteristics and time domain changes of different geographic areas by constructing a virtual and real scene three-dimensional geographic environment, so that the learning, working, research and other efficiency is improved, and the method is more beneficial for related personnel to assist in decision making. Image ghosts are few, and the 3D effect is prominent. And multiple persons can watch and experience at the same time.