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Nano-silver mouth wash for preventing and treating oral diseases and preparation method thereof

A technology for oral diseases and nano-silver, which is used in oral care, respiratory system diseases, antiviral agents, etc., can solve the problems of large toxic and side effects, adverse effects, insufficient local concentration, etc. Produce simple effects

Inactive Publication Date: 2013-11-13
阎昭良
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the suitable temperature and humidity in the oral cavity and sufficient nutrients, the number of pathogenic microorganisms is huge, various and interact with each other, making the prevention and treatment of oral and throat diseases difficult. In addition, there are more and more drug-resistant bacteria and a large number of metabolites of harmful bacteria. In the oral mucosa, the active ingredients of the drug are difficult to reach the lesion, and the duration of the drug effect is short and other unfavorable factors. Therefore, the drug has a small adaptability range in the prevention and treatment of oral and throat diseases, and the local concentration is not enough. And other issues
Toothpaste and mouthwash in the prior art are mostly products for cleaning the oral cavity, which mainly clean and care for teeth and periodontal tissue. Drug toothpaste and mouthwash containing active ingredients of medicine also have the same adverse effects as drug prevention and treatment.

Method used

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  • Nano-silver mouth wash for preventing and treating oral diseases and preparation method thereof
  • Nano-silver mouth wash for preventing and treating oral diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Embodiment 1: The said nano silver mouthwash for preventing and treating oral diseases, which comprises the following components:

[0016] 10000g deionized water containing 0.1ppm-1000ppm; hemostatic agent: tranexamic acid 1g-500g; local anesthetic: benzocaine 1g-500g; bacteriostatic agent: compound paraben 1g-1000g; dispersant: cross Low-substituted hydroxypropyl cellulose 5g-1250g, croscarmellose sodium 5g-1250g; thickener: sodium alginate 5g-1250g, polyethylene glycol 5g-1250g; wetting agent: Tween 5g- 750g, sodium lauryl sulfate 5g-750g; cooling agent: menthol 10g-1000g; adhesive: micronized silica gel 5g-1750g, microcrystalline cellulose 5g-1750g; flavoring agent: aspartame 1g-500g; Coloring agent: brilliant blue 1g-500g.

[0017] The preparation process is as follows:

[0018] Step 1: Take nano-silver, tranexamic acid and benzocaine in proportion to weigh and mix.

[0019] Step 2: Weigh the bacteriostatic agent, dispersant, thickener, wetting agent, cooling agent, and a...

Embodiment 2

[0023] Embodiment 2: The said nano silver mouthwash for preventing and treating oral diseases, which comprises the following components:

[0024] 10000g deionized water containing 0.1ppm-1000ppm; hemostatic agent: tranexamic acid 1g-500g; local anesthetic: benzocaine 1g-500g; bacteriostatic agent: compound paraben 1g-1000g; dispersant: cross Low-substituted hydroxypropyl cellulose 5g-1250g, poloxamer 5g-1250g; thickener: polyethylene glycol 5g-1250g, betacyclodextrin 5g-1250g; wetting agent: Tween 5g-750g , Sodium dodecylbenzene sulfonate 5g-750g; Cooling agent: Menthol 10g-1000g; Adhesive: Microcrystalline cellulose 5g-1750g, Pregelatinized starch 5g-1750g; Flavoring agent: Aspartame 1g -500g; colorant: brilliant blue 1g-500g.

[0025] The preparation process is as follows:

[0026] Step 1: Take nano-silver, tranexamic acid and benzocaine in proportion to weigh and mix.

[0027] Step 2: Weigh the bacteriostatic agent, dispersant, thickener, wetting agent, cooling agent, and adhesio...

Embodiment 3

[0031] Embodiment 3: The said nano silver mouthwash for preventing and treating oral diseases, which comprises the following components:

[0032] 10000g deionized water containing 0.1ppm-1000ppm; hemostatic agent: tranexamic acid 1g-500g; local anesthetic: benzocaine 1g-500g; bacteriostatic agent: compound paraben 1g-1000g; dispersant: cross Sodium carboxymethyl starch 5g-1250g, poloxamer 5g-1250g; thickener: sodium alginate 5g-1250g, beta cyclodextrin 5g-1250g; wetting agent: sodium lauryl sulfate 5g- 750g, sodium dodecylbenzene sulfonate 5g-750g; cooling agent: menthol 10g-1000g; adhesive: micronized silica gel 5g-1750g, pregelatinized starch 5g-1750g; flavoring agent: aspartame 1g- 500g; Coloring agent: brilliant blue 1g-500g;

[0033] The preparation process is as follows:

[0034] Step 1: Take nano-silver, tranexamic acid and benzocaine in proportion to weigh and mix.

[0035] Step 2: Weigh the bacteriostatic agent, dispersant, thickener, wetting agent, cooling agent, and adhes...

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Abstract

The invention relates to the technical field of daily consumer goods for killing malignant bacteria, viruses and funguses in oral cavity and throat, cleaning the oral cavity and preventing and treating oral diseases, and in particular relates to nano-silver mouth wash for preventing and treating oral diseases and a preparation method thereof. The mouth wash is characterized by comprising 0.1ppm-1000ppm nano silver and the following components in percentage by weight: 0.01-5% of a hemostatic, 0.01-5% of a topical anaesthetic, 0.01-10% of a bacteriostatic agent, 0.1-25% of a dispersant, 0.1-25% of a thickener, 0.1-15% of a wetting agent, 0.1-10% of an algefacient, 0.1-35% of an adhesive agent, 0.01-5% of a corrigent and 0.01-5% of a colorant. The principle is as follows: silver particles with diameter of 10-50 nanometers can be absorbed to cytomembranes of harmful microorganisms to damage protein capsids and DNA (Deoxyribonucleic Acid) molecules of the harmful microorganisms to lead to death of the harmful microorganisms by interfering metabolism of the harmful microorganisms, so that the nano-silver mouth wash has broad spectrum sterilizing and bacteriostatic effect, is durable and effective in effect, free from toxic and side effects as well as drug resistance, safe and reliable, convenient to use, simple in production and preparation, and has very good preventing and treating effect to periodontal disease, acute and chronic aryngitis and oral mucosal diseases.

Description

Technical field [0001] The present invention relates to the technical field of daily consumer goods used to kill harmful bacteria, viruses, and fungi in the oral and throat, prevent oral diseases, clean, and prevent oral diseases, in particular to a nano silver mouthwash for preventing oral diseases and a preparation method thereof . Background technique [0002] There are more than 100 kinds of harmful microorganisms in the mouth and throat. Common viruses include adenovirus, herpes virus, influenza virus, mumps virus, parainfluenza virus, hepatitis virus and Chlamydia pneumoniae. Common harmful bacteria mainly include catarrhalis, gingival carbon dioxide cellophages, hemolytic carbon dioxide cellophages, sputum-producing carbon dioxide cellophages, Corynebacterium diphtheria, Corynebacterium ulcerans, Escherichia coli, Clostridium gingivalis, Haemolytic Haemolyticus, Influenza Haemophilus, Helicobacter pylori, Neisseria mucin, Neisseria gonorrhoeae, Streptococcus pyogenes, Sto...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/81A61K8/44A61K8/19A61Q11/00A61P1/02A61P31/04A61P31/10A61P31/12A61P11/04
Inventor 阎昭良
Owner 阎昭良
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