Tumors can be treated with an alternating electric field. The size of cells in the tumor is determined prior to the start of treatment by, for example, biopsy or by inverse electric impedance tomography. A treatment frequency is chosen based on the determined cell size. The cell size can be determined during the course of treatment and the treatment frequency is adjusted to reflect changes in the cell size. A suitable apparatus for this purpose includes a device for measuring the tumor impedance, an AC signal generator with a controllable output frequency, a processor for estimating the size of tumor cells and setting the frequency of the AC signal generator based thereon, and at least one pair of electrodes operatively connected to the AC signal generator such that an alternating electric field is applied to the tumor.
Tumors can be treated with an alternating electric field. The size of cells in the tumor is determined prior to the start of treatment by, for example, biopsy or by inverse electric impedance tomography. A treatment frequency is chosen based on the determined cell size. The cell size can be determined during the course of treatment and the treatment frequency is adjusted to reflect changes in the cell size. A suitable apparatus for this purpose includes a device for measuring the tumor impedance, an AC signal generator with a controllable output frequency, a processor for estimating the size of tumor cells and setting the frequency of the AC signal generator based thereon, and at least one pair of electrodes operatively connected to the AC signal generator such that an alternating electric field is applied to the tumor.
Voltage sources produce desired current patterns in an ACT-type Electrical ImpedanceTomography (EIT) system. An iterative adaptive algorithm generates the necessary voltage pattern that will result in the desired current pattern. The convergence of the algorithm is shown under the condition that the estimation error of the linear mapping from voltage to current is small. The simulation results are presented along with the implication of the convergence condition.
A method is provided for taking electrical impedancetomography measurements using multiple electrodes located at selected positions external to a volume of a subject body. Multiple orthogonal or near-orthogonal signals are introduced simultaneously by way of selected different electrodes and resultant predetermined responses (if any) at receiving electrodes are recorded or determined. The signals are encoded using the technique of code division multiplexing and received signals at each receiving electrode are cross-correlated with original signals to determine the contribution of each original signal to a composite received signal. The invention also relates to apparatus suitable for use in applying a method.
In a method of electrical impedancetomography (EIT), a mediating fluid provides electrical contact between the electrodes of an EIT device and the skin of a body part to be examined. The height of the fluid is raised or lowered between impedance measurements, enabling tomographic images of the tissue under examination to be resolved mathematically for subsequent viewing. Tomographic planes are isolated by calculating differences between Cartesian models generated from impedance values measured at the plane of interest and at an adjacent plane.
The invention discloses a calibration device for an electric impedance tomographysystem. The calibration device comprises basic impedance units for simulating impedance distribution or the disturbance of the impedance distribution and electrode / skin contact units for simulating electrode / skin contact characteristics, wherein the basic impedance units are distributed to form a calibration network with a known conductivity; at least four layers of basic impedance units are arranged from the central point to the edges of the calibration network; and the electrode / skin contact units are formed by electrode / skin contact impedance modules and electrode polarization potential simulation modules, distributed around the calibration network at equal interval and connected with the basic impedance units on the outermost layer of the calibration network. The device provided by the invention can meet the evaluating requirements of performance and an image reconstruction effect of an electric impedance tomographydata acquisitionsystem.
The invention provides a multi-depth layer electrical impedancetomography imaging system which detects a plurality of subcutaneous tomograms paralleling to different depth layers on the surface of the skin by the measurement of voltage amplitudes of a plurality of different electrodes. When in practical medical inspection, the subcutaneous practical impedance information of a human body is reconstructed by the measurement of the voltage amplitudes of the plurality of different electrodes. Firstly, a plurality of tomograms paralleling to the contact surface of the skin and an electrode disk and under the electrodes are set. The depth of each tomogram can be preset according to detection demands, and then all tomograms are respectively dissected, i.e. all tomograms are dissected into a plurality of small areas. The detection purpose for obtaining the corresponding impedance value of all small areas in all set tomograms can be achieved, and the impedance values are showed by a picture so as to obtain the tomography information of a plurality of subcutaneous tomograms paralleling to different depth layers on the surface of the skin.
There is disclosed a system of electrodes used for transdermal conduction of electrical signals and a method of use thereof, the system comprising a plurality of electrode parts connected by means of electrical conductors to electric impedance tomography apparatuses, as well as other devices, the parts being secured to an outer side of a flexible and porous blade coated on both sides thereof by layers of electrically conductive and adhesive materials, such electrically conductive and adhesive materials being in mutual contact through the pores of the blade, the inner face of the latter being removably secured, by means of adhesion, to the patient. The invention comprises means for positioning the electrode parts, as well as means for external protection thereof and of their respective conductors.
There is suggested a system for automated adjustment of a pressure set by a respiration device, in particular a positive end-expiratory pressure and / or a maximum airway pressure, comprising: an arrangement for electrical impedancetomography for detecting an electrical impedance distribution along at least a two-dimensional cross-section through the human thorax at least at the end of an inspiration phase and at the end of an associated expiration phase; a device for dividing the detected electrical impedance distribution at the end of the inspiration phase and at the end of the expiration phase into a plurality of EIT pixels and for determining a value of the electrical impedance at the end of the inspiration phase and at the end of the expiration phase, as associated with a respective EIT pixel; and a device for automated adjustment of the pressure set by the respiration device on the basis of a comparison (i) of a deviation between the value of the electrical impedance at the end of the inspiration phase associated with an individual EIT pixel and the value of the electrical impedance at the end of the expiration phase associated with the respective individual EIT pixel (ii) with a deviation between the value of the electrical impedance at the end of the inspiration phase and the value of the electrical impedance at the end of the expiration phase, as determined on the basis of the entirety of EIT pixels.
There is disclosed a system of electrodes used for transdermal conduction of electric signals and a method of use thereof, the said system comprising a plurality of electrode parts (17, 58, 58′) connected by means of electrical conductors (17′, 68) to electric impedance tomography apparatuses, as well as other devices, the said parts being secured to the outer side (15a, 54a, 54′a) of a flexible and porous blade (15, 54c, 51′) coated on both sides thereof by layers of electrically conductive and adhesive materials, such electrically conductive materials being in mutual contact through the pores (74) of the said blade, the inner face of the latter being removably secured, by means of adhesion, to the skin of the patient (65). The invention comprises means for positioning the said electrode parts, as well as means for external protection thereof and of their respective conductors.
The invention discloses an electric impedance tomography method of a brain based on layered reconstruction, which comprises the steps as follows: layering a head model; layering the head model as a scalp layer omegascalp, a skull layer omegaskull and a brain layer omega brain according to space distribution prior information; introducing a constraint matrix D to further layer and reconstruct so as to reduce artificial images of the skull layer; and layering and reconstructing the reconstructed head model in a second step to further reduce the interference of the scalp layer and highlight the target in the brain. By means of concept of layered image reconstruction, the method has the benefits of reducing the skull artificial images, lowering the interference of the scalp layer and improving the imaging quality.
Tumors can be treated with an alternating electric field. The size of cells in the tumor is determined prior to the start of treatment by, for example, biopsy or by inverse electric impedance tomography. A treatment frequency is chosen based on the determined cell size. The cell size can be determined during the course of treatment and the treatment frequency is adjusted to reflect changes in the cell size. A suitable apparatus for this purpose includes a device for measuring the tumor impedance, an AC signal generator with a controllable output frequency, a processor for estimating the size of tumor cells and setting the frequency of the AC signal generator based thereon, and at least one pair of electrodes operatively connected to the AC signal generator such that an alternating electric field is applied to the tumor.
The invention provides a focused type electric impedance tomographysignal detection system. Focused electrode arrays (1) are evenly distributed around a three-dimensional research object, and the output end of an excitation current source module, the output end of a focusing current source module and the input end of a signal detection processing module are connected with the focused electrode arrays (1). The output end of a control module is connected with the focused electrode arrays (1), the input end of the excitation current source module, the input end of the focusing current source module and the input end of the signal detection processing module. The input end of an electric impedance tomographyalgorithm module is connected with the output end of the signal detection processing module. By means of focused electrode bodies (5 and 6) distributed at the two ends of a focused electrode, current is injected into the three-dimensional research object, a current shielding face is formed in the object, three-dimensional divergency of current injected into main electrodes (2) is limited, and conductivity distribution of the whole three-dimensional research object is inverted by solving section conductivity information of a circulation interface S where the main electrodes (2) inject current.
A process with a corresponding device for lung ventilation involves recording an image of the lung status with an electric impedance tomography (EIT) system (2) and the total area of ventilated lung areas is determined by a computing unit (4) from all image values, subsequently divided into at least two lung areas and the extent of the homogeneity of the ventilated lung areas is determined by comparison of the impedance changes within these areas. In case of a homogeneity rated as being too low, the respiration pressures are increased step by step by means of the respirator (1) and the respiration pressure at which the greatest possible homogeneity is obtained from subsequently determined status images is determined by means of the EIT system (2). The respiration pressure is subsequently lowered again by the respirator (1) until the computing unit (4) detects a reduction in the homogeneity of ventilated lung areas, so that the respiration pressure is subsequently increased again by means of the respirator (1) to the last value at which no reduction in the homogeneity of the ventilated lung areas occurred.
An electric impedance tomography device with chest electrodes, a display and a control and analyzing unit to determine a time series of a global ventilation curve from the sequence of reconstructed matrices as a time series of the mean impedance change or of a measured respiration volume, to divide an inspiration or expiration phase into a number of steps of equal volume change, to determine the times corresponding to these steps, to determine the change in local impedance between these times for each image element, the ratio of this local change in impedance to the global equal volume change to form a local sequence of relative impedance changes of the image element as a function of the steps of equal volume change, to determine a scalar indicator characteristic as a function of the steps of equal volume change and to display each image element based on the respective scalar indicator.
The invention relates to an electric impedance tomography optimization algorithm based on fuzzy clustering, which comprises the following steps: (1) obtaining an image matrix of the electric impedancetomography; (2) extracting a feature representing each pixel information from the image matrix, wherein the feature 1: a mean vector, that is, the mean value of each boundary voltage value corresponding to each pixel point; Feature 2: variance matrix, on the basis of the mean matrix, calculating the variance of each pixel, each pixel 2-dimensional eigenvector to form the eigenmatrix; (3) fuzzy clustering being carried out by using the feature matrix as the input data set of the fuzzy clusteringalgorithm, and the membership degree value of each pixel point being obtained, and the membership degree value of each pixel point to each class being characterized; according to the degree of membership matrix, the classification being judged.
The present invention relates to a method for performing electrical impedancetomography (EIT) by an MR system, wherein during the MR measurement continuous RF signals for an EIT measurement are emitted by at least one RF coil of the MR system, and continuous RF signals modulated by the object undergoing examination are received by the receiving coils of the MR system. An image of the object undergoing examination is determined, based on the modulated continuous RF signals, by an EIT technique.
A system, instrumentality, and method for performing an oral care evaluation of a user via electrical impedancetomography (EIT). For example, a system may include an oral care device having a first member housing a first electrode. The first electrode may be configured to transmit a first signal through a gingiva of a user to cause an altered first signal. The oral care device may have a second member housing a second electrode. The second electrode may be configured to receive the altered first signal. The system may be configured to generate an electrical impedancetomography (EIT) profile of the gingiva of the user, for example, based on data indicative of the first signal and the altered first signal. An oral health characteristic of the user may be determined based on the EIT profile of the gingiva of the user.
A great device (10) processes and visualizes electrical impedancetomography (EIT) data (3) of at least one region of the lungs for determining and visualizing regional properties of the lungs of a living being. The EIT data (3) are obtained from an electrical impedancetomography apparatus (30). The device makes it possible to visualize regional properties of the lungs or of regions of the lungs in terms of hyperdistension or collapse.
An electrical impedancetomography device (1) includes an electrode array, including a plurality of electrodes (33) arranged spaced apart from one another, a signal feed unit (51) and a signal acquisition unit (50). A calculation and control unit (70) is configured to determine a situation with an axial twist angle of the electrode array on a thorax (34) of a human being and to provide a control signal (79), which indicates the situation with axial twist angle of the electrode array. The calculation and control unit (70) may be configured as a central unit or an array of distributed units (cloud computing) in order to determine and to provide the axial twist angle.