A method, computer program product, and computing system device for receiving, at a computing device, a plurality of candidate therapy options, a corpus of therapy data, and a set of therapy recipient cohorts. At least a portion of therapy data may be filtered from the corpus of therapy data based upon, at least in part, the plurality of candidate therapy options and the set of therapy recipient cohorts. A graph may be generated to include a plurality of nodes representative of the plurality of candidate therapy options and a plurality of connections between the plurality of nodes indicating a sentiment factor with respect to the plurality of candidate therapy options based upon, at least in part, the at least a portion of therapy data filtered from the corpus of therapy data. Using the graph, a ranked list of the plurality of candidate therapy options may be generated.