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Antioxidative anti-aging SOD nano-selenium peptide composition and preparation method thereof

A peptide composition and nano-selenium technology, applied in biochemical equipment and methods, drug combinations, redox enzymes, etc., can solve problems such as no integration and cumbersome process flow, so as to improve absorption utilization and promote nutrient absorption rate, absorption enhancement effect

Inactive Publication Date: 2016-10-12
谭智洋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] There are some medicines and health foods containing SOD on the market, and many of them have applied for invention patents. For example, the patent No. ZL200610044379.1 discloses a SOD health care composition, which uses SOD and VC, VE, pollen And Polygonum multiflorum and Polygonatum extracts are mixed and compounded to obtain a health care composition with functions such as anti-oxidation, anti-aging, anti-fatigue, enhancing immunity, and lowering fat; Patent No. ZL200810112887.8 discloses a SOD composite capsule and its preparation method, This patent uses SOD enzyme preparation extracted from tadpoles, mixed with resveratrol, coenzyme Q10, foie gras extract, wheat germ extract, safflower extract, tartary buckwheat extract, and then packed into capsules. Oxidation function, but the process is cumbersome; Patent No. ZL201010604957.9 discloses an anti-aging, antihypertensive, lipid-lowering SOD pharmaceutical composition and its preparation method. The patent mainly uses ginseng powder, Tianqi powder, safflower powder, ginkgo powder After mixing with pine bark extract, drying and sterilizing, add SOD and mix well to make a capsule preparation; Patent No. ZL201110197534.4 discloses SOD collagen peptide beauty and anti-aging agent. The patent uses natural plant SOD and collagen peptide, The rational combination of hyaluronic acid, pearl powder and ginsenoside extract has the effects of activating cell function, improving immunity and beautifying and anti-aging; patent No. ZL201110254795.5 discloses a SOD composite capsule and its preparation method. Select SOD, ginseng extract, pearl powder, Codonopsis pilosula extract, safflower extract, Jiaogulan extract, spirulina, pine bark extract and Lycium barbarum polysaccharide to make enteric-coated capsules. The product can delay aging and enhance the body's immunity effect; Patent No. ZL201210179382.X discloses an oral biological drug for the treatment of chemotherapy and radiotherapy syndrome and its preparation method. The patent mainly uses recombinant human superoxide dismutase (rhSOD), mannose, trehalose, metal sulfur Protein, vitamin C and vitamin E are used as raw materials, and processed through step-by-step dissolving, filtering, freeze-drying and other steps to process the powdery oral biological new drug. and good anti-oxidative properties
The product formulations involved in these patent applications are different, but the production process is similar. Most of them supplement and regulate the SOD activity of the human body by adding Chinese herbal extracts to SOD, and some of them combine SOD with other antioxidants (such as Vitamin C and vitamin E) synergistically remove oxygen free radicals in the body, which does not involve the integration of exogenous SOD, enzyme active center elements, active small peptides and functional oligosaccharides, and through scientific formulations, synergistic Synergy to comprehensively improve and enhance the body's SOD activity
Therefore, there are deficiencies in the prior art scheme aspect product prescription and curative effect

Method used

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  • Antioxidative anti-aging SOD nano-selenium peptide composition and preparation method thereof
  • Antioxidative anti-aging SOD nano-selenium peptide composition and preparation method thereof
  • Antioxidative anti-aging SOD nano-selenium peptide composition and preparation method thereof

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preparation example Construction

[0070] Another object of the present invention is to provide a preparation method of anti-oxidation and anti-aging SOD nano-selenopeptide composition, which is characterized in that: the composition contains SOD, hemoglobin peptide, oligosaccharides, nano-selenium, zinc gluconate, Manganese gluconate and copper gluconate, the content of each component in each 100g composition is: SOD1.5-6.5 million activity units, hemoglobin peptide 35-70g, oligosaccharides 15-50g, nano-selenium 4-8mg, zinc gluconate 5000- 7200mg, manganese gluconate 1000-2200 mg, copper gluconate 600-1200 mg, including the following process steps:

[0071] (1) Preparation of SOD and hemoglobin powder:

[0072] A. Preparation of hemoglobin solution: collect qualified fresh pig blood, add sodium citrate for anticoagulant treatment, collect red blood cells by centrifugation, then add deionized water with 1 times the volume of red blood cells, and continue to stir for hemolysis for 1 hour to obtain hemoglobin sol...

Embodiment 1

[0123] The preparation method of this anti-oxidation and anti-aging SOD nano selenopeptide composition is characterized in that: the composition contains SOD, hemoglobin peptide, fructooligosaccharide, nano selenium, zinc gluconate, manganese gluconate, copper gluconate, The content of each component in the composition is: 20 million activity units of SOD, 500 g of hemoglobin peptide, 400 g of fructooligosaccharide, 70 mg of nano selenium, 50 g of zinc gluconate, 12 g of manganese gluconate, and 7 g of copper gluconate.

[0124] The specific preparation process steps of this anti-oxidation and anti-aging SOD nanometer selenopeptide composition are as follows:

[0125] (1) Preparation of SOD and hemoglobin powder:

[0126] A. Preparation of hemoglobin solution: Collect 100L of qualified fresh pig blood, add 0.5% sodium citrate by weight of fresh pig blood as anticoagulant, centrifuge at 16300r / min in a tubular centrifuge, collect 46L of red blood cells, and then add blood Deio...

Embodiment 2

[0143] The preparation method of this anti-oxidation and anti-aging SOD nano-selenopeptide composition is characterized in that: the composition contains SOD, hemoglobin peptide, isomaltooligosaccharide, nano-selenium, zinc gluconate, manganese gluconate, gluconic acid Copper, the content of each component in the composition is: SOD40 million activity units, hemoglobin peptide 680g, isomaltooligosaccharide 200g, nano selenium 60mg, zinc gluconate 60g, manganese gluconate 15g, copper gluconate 9g.

[0144] The specific preparation process steps of this anti-oxidation and anti-aging SOD nanometer selenopeptide composition are as follows:

[0145] (1) Preparation of SOD and hemoglobin powder:

[0146] A. Preparation of hemoglobin solution: Collect 200L of qualified fresh pig blood, add 0.5% sodium citrate by weight of fresh pig blood for anticoagulation, collect 89L of red blood cells by centrifugation at 16300r / min in a tubular centrifuge, and then add red blood cell volume 1 t...

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Abstract

The invention relates to an antioxidative anti-aging SOD nano-selenium peptide composition. Every 100 g of the composition is prepared from a million and a half activity units to six million and a half activity units of SOD, 35-70 g of hemoglobin peptide, 15-50 g of oligosaccharide, 4-8 mg of nano-selenium, 5,000-7,200 mg of zinc gluconate, 1,000-2,200 mg of manganese gluconate and 600-1,200 mg of copper gluconate. A preparation method of the composition comprises the steps that firstly, the SOD and the hemoglobin peptide are prepared by taking swine erythrocytes as a raw material, and nano-selenium is prepared by taking the oligosaccharide as a medium template; secondly, the hemoglobin peptide is subjected to a chelation reaction with nano-selenium, zinc gluconate, manganese gluconate and copper gluconate to prepare hemoglobin peptide chelation powder; thirdly, the SOD, oligosaccharide and the hemoglobin peptide chelation powder are mixed to obtain the SOD nano-selenium peptide composition, and the SOD nano-selenium peptide composition can be prepared into conventional orally-taken preparations such as powder, tablets and capsules as needed. According to the antioxidative anti-aging SOD nano-selenium peptide composition, drugs are scientifically used to form a prescription, the organism SOD activity and content are enhanced and increased respectively from the three aspects including conditioning, nourishing and tonifying, free radicals in a body can be significantly scavenged, the malondialdehyde (MDA) content is decreased, and therefore the effects of resisting oxidation and aging and enhancing the immunity are achieved.

Description

technical field [0001] The invention relates to a health food, in particular to an anti-oxidation and anti-aging SOD nanometer selenopeptide composition and a preparation method thereof. Background technique [0002] The human body will produce too many active free radicals due to factors such as aging, disease, trauma, environmental pollution, unhealthy lifestyle, and chemical drugs. Excessive free radicals will cause membrane damage and the formation of cross-link bonds, denaturing proteins in the body , Nucleic acid metabolism disorder, bio-enzyme destruction, hormones are oxidized, and lead to the loss of membrane function, a large amount of aging pigments accumulate in lysosomes, and a large amount of lipid peroxide (LPO) and malondialdehyde (MDA) are produced, causing various organs of the body to Damage and loss of function, leading to aging of the body and various diseases. A large number of scientific studies have shown that a series of oxidation and peroxidation r...

Claims

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Application Information

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IPC IPC(8): A23L33/00A23L33/10A23L33/18A23L33/125A23L33/16A61K38/44A61P37/04A61P39/06A61K38/42A61K33/04A61K33/30A61K33/32A61K33/34A61K31/702
CPCA23V2002/00A61K31/702A61K33/04A61K33/30A61K33/32A61K33/34A61K38/42A61K38/446C12Y115/01001A23V2200/302A23V2200/324A23V2200/30A23V2250/1588A23V2250/1626A23V2250/1642A23V2250/1612A23V2250/55A61K2300/00
Inventor 陈石良
Owner 谭智洋
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