43 results about "Azo coupling" patented technology

The present invention describes methods for preparing aqueous colored pigment dispersions comprising the step of combining, in any order, a) a colored pigment, b) an azo coupler, c) an aromatic amine, d) a diazotizing agent, and e) an aqueous medium, wherein the aromatic amine comprises as least one ionic group, at least one ionizable group, or a mixture of at least one ionic group and at least one ionizable group. These colored pigment dispersions are particularly useful as an inkjet ink composition. Also disclosed are inkjet ink compositions comprising a) a liquid vehicle, b) a colored pigment, and c) a dispersant having the formula:

D-N═N-AC,

wherein AC is an azo coupling component and D is a diazo component comprising at least one ionic group, at least one ionizable group, or a mixture of at least one ionic group or ionizable group.

The invention provides a preparation method of hydroxymethyl substitutent o-alkyl biphenyl and intermediate thereof, which takes halogen o-alkyl biphenyl as a raw material to synthesize halogen o-alkyl biphenyl through diazonium coupling reaction. The raw materials and catalyst utilized by the invention are massively commercialized at home and abroad and all around the world with low price. The method of the invention has low production cost, short synthetic route, mild reaction condition, easy and feasible operation process, less three wastes (waste gas, waste water and industrial residue) generation, low cost of raw materials and high yield and purity, thereby being favorable to industrial volume production.

Aqueous green inkjet ink compositions are prepared from aqueous organic pigment dispersions for use in various inkjet printing methods. In particular, these methods provide a green image or expanded color gamut for other inkjet printed colors. The aqueous organic pigment dispersion contains a green copper phthalocyanine pigment and an azo-coupled β-ketoamide pigment and an organic pigment dispersant. The weight ratio of the green copper phthalocyanine pigment to the azo-coupled β-ketoamide pigment is from 1:1 to 10:1. The median particle diameter of each of the green copper phthalocyanine pigment and the azo-coupled β-ketoamide pigment is less than 85 nm. At least 95% of the total particles of each of the green copper phthalocyanine pigment and the azo-coupled β-ketoamide pigment have a particle diameter of less than 150 nm.

The invention is directed to an electrophotographic toner or developer, powder coating, ink jet ink or an electronic media having an azo colorant prepared by conducting the diazotization of aromatic or hetaromatic amines or the azo coupling reaction or the diazotization and the azo coupling reaction in a microreactor.

The invention discloses a graphene/phthalocyanine supercapacitor electrode material, and a preparation method thereof. The method mainly comprises the following steps: obtaining graphene oxide (GO) through the chemical oxidation method, and using p-phenylenediamine (pPD) as a reducing agent to obtain reduced GO-pPD (rGO-pPD) under the action of strong ammonia water; and carrying out azo-coupling reaction of the rGO-pPD and 2,9,16,23-tetraamino nickel (II) phthalocyanine (NiTAPc) with outstanding photoelectric property to obtain a covalently grafted binary composite material, i.e., rGO-p-Pc. The material and the preparation method thereof provided by the invention have the advantages that the method is simple and convenient to operate, and the yield rate reaches 95%; and the specific capacitance of the electrode material reaches 600F.g<-1>, and the cyclic stability is high.

The invention discloses a preparation method of eltrombopag olamine (Eltrombopag). The preparation method comprises the following steps: carrying out azo coupling reaction by using 3'-amino-2'-hydroxy-biphenyl-3-carboxylic acid (II) and acetoacetic acid alkyl ester to obtain (Z)-2-[3'-(2'-hydroxyl-3-hydroxy-biphenyl) hydrazono]-3-oxo acid alkyl ester (III); carrying out condensation cyclization reaction on an intermediate (III) and 3,4-dimethyl benzene hydrazine to prepare the eltrombopag olamine (I). The method is concise in process, available in raw material, economical and environmental friendly, and beneficial to achievement of industrialization, and economic and technological development of the eltrombopag olamine crude drug can be facilitated.

The invention discloses a silver ion-doped azo conjugated microporous polymer, a preparation method and application, which belong to the technical field of polymer material preparation. Specifically,with 4-(1,2,2-tri(4-aminophenyl)vinyl)aniline and phloroglucinol as comonomers, under the catalysis of concentrated hydrochloric acid, coupling is carried out by diazo-coupling reaction, silver ions are then loaded, and thereby the silver ion-doped azo conjugated microporous polymer is prepared. The polymer prepared by the invention shows excellent adsorption capability on iodine molecules, moreover, the performance of the polymer is excellent in aspects such as detecting heavy metal ions Cu<2+>, Hg<2+>, Cr<3+> and Ni<2+>, and the polymer has potential application value in fields such as iodine adsorption and heavy metal ion detection.

An aqueous organic pigment dispersion contains a green copper phthalocyanine pigment and an azo-coupled β-ketoamide pigment. It also includes an organic pigment dispersant at 40 weight % to 100 weight %, based on the sum of the weights of the organic pigments. The weight ratio of the green copper phthalocyanine pigment to the azo-coupled β-ketoamide pigment is from 1:1 to 10:1. The median particle diameter of each of the green copper phthalocyanine pigment and the azo-coupled β-ketoamide pigment is less than 85 nm. At least 95% of the total particles of each of the green copper phthalocyanine pigment and the azo-coupled β-ketoamide pigment have a particle diameter of less than 150 nm. This dispersion can be used to prepare aqueous green inkjet ink compositions that can be used in various inkjet printing methods.

The invention relates to a main chain azobenzene type organic porous polymer material and a preparation method thereof and belongs to the field of new materials. The structural formula of the organicporous polymer material is shown in the description. The method comprises the steps as follows: dispersing aryl diamine in a first solvent at ice-water bath temperature, adding an acid medium after uniform dispersion to enable aryl diamine to be completely dissolved; dropwise adding a nitrosation agent for a diazotization reaction to obtain diazonium salt; adjusting the Ph value of the diazonium salt solution to be neutral by an alkaline solution to obtain a neutral solution; dissolving aryl diphenol in a second solvent, then, dropwise adding the solution to the neutral solution for an azo coupling polymerization reaction, and performing treatment to obtain the organic porous polymer material. The preparation method has the characteristics that preparation is simple, raw materials are easyto obtain, the reaction condition is mild and the like. The obtained main chain azobenzene type organic porous polymer material has the characteristics of solubility, good thermal stability, high specific surface area, large pore volume and the like.

The present invention provides a process for preparing uncoated, readily dispersible C.I. Pigment Red 112 by azo coupling in a microreactor, which comprises precipitating the coupling component in an upstream microreactor and coupling the precipitated coupling component in finely divided form to the diazo component in a microreactor. The C.I. Pigment Red 112 of the invention features low dispersion harshness in alkyd resin varnish, and a PCB content of below 25 ppm.

The invention discloses a method for detecting tyramine content in aquatic products based on the azo coupling reaction and the surface enhanced resonance Raman scattering. The method for detecting tyramine content in aquatic products based on the azo coupling reaction and the surface enhanced resonance Raman scattering is characterized by comprising the following steps: taking fresh fish meat andadding trichloroacetic acid solution for homogenate, shaking at room temperature, then centrifuging to take the supernatant, repeatedly extracting the residue with the trichloroacetic acid solution, merging the supernatant to make up the volume, and passing a filtering membrane, so as to obtain a sample solution to be detected; adding a NaNO<2> solution to a mixture obtained by dissolving para aminobenzoic acid in a HCl solution, and quickly adding a Na<2>CO<3> solution and a tyramine solution to carry out the tyramine azo coupling reaction under a stirring condition after the reaction, so asto obtain a tyramine-derived azo compound solution; and mixing the tyramine-derived azo compound solution with Au@Ag NPs solution in proportion to perform spectral detection, and calculating the tyramine content in the sample to be detected according to the linear relationship between the tyramine concentration and the characteristic peak signal intensity. The advantages of the method for detecting tyramine content in aquatic products based on the azo coupling reaction and the surface enhanced resonance Raman scattering are simple, fast and high-sensitivity.

The invention discloses a method for detecting bisphenol A in a water environment on the basis of an azo coupling reaction. The method comprises the following steps: 1, clenbuterol hydrochloride is added to a sodium nitrite solution under an acidic condition for diazotization; 2, bisphenol A with different concentrations is added, dilute ammonia water is added, and secondary water is added for dilution; 3, the reaction liquid in the step 2 has a visible absorption peak at 410 nm; bisphenol A is detected with a spectrophotometric method; 4, the reaction liquid in the step 2 has strong fluorescence emission at 305 nm, and the fluorescence signals are enhanced 3.2 times than those of bisphenol A with the same concentration. With adoption of the method, the absorbance and the fluorescence signals are enhanced multiple times than those of bisphenol A with the same concentration, and the sensitivity of a fluorescence method and the spectrophotometric method for detecting bisphenol A is improved; the method is simple, fast and good in selectivity, can be used for detecting bisphenol A in the water environment and avoids use of an organic solvent.

Novel biomolecular conjugates containing non-natural aromatic chemical moieties covalently coupled to a diazonium compound and methods of their use are disclosed.

An aqueous organic pigment dispersion contains a green copper phthalocyanine pigment and an azo-coupled β-ketoamide pigment. It also includes an organic pigment dispersant at 40 weight % to 100 weight %, based on the sum of the weights of the organic pigments. This aqueous organic pigment dispersion can be combined with a humectant to provide an aqueous green inkjet ink composition. The weight ratio of the green copper phthalocyanine pigment to the azo-coupled β-ketoamide pigment is from 1:1 to 10:1. The median particle diameter of each of the green copper phthalocyanine pigment and the azo-coupled β-ketoamide pigment is less than 85 nm. At least 95% of the total particles of each of the green copper phthalocyanine pigment and the azo-coupled β-ketoamide pigment have a particle diameter of less than 150 nm. The aqueous green inkjet ink compositions can be used in various inkjet printing methods.

The invention provides a novel photochromic azobenzene compound and a synthesis method thereof and relates to a novel compound N-[4-[2-(4-methoxyphenyl) diazenyl] phenyl]-2-nitroaniline with a photochromic property and a synthesis method of the novel compound. The synthesis method comprises diazonium coupling reaction and coupling reaction between aromatic amine and aromatic halides. According to the invention, coupling reaction conditions of aromatic amine and aromatic halides are very simple, to be specific, only alkali metal fluorides with equal molar mass are added into reaction liquid, and reflux is carried out at 130 DEG for 3 h; a solvent is not required to be subjected to anhydrous anaerobic treatment, that reaction is carried out under nitrogen or argon atmosphere is not required, no side reaction is generated, aftertreatment of the product is simple, the conversion rate is higher, the yield of the target product is 48-74%, in addition, equipment adopted by the invention is relatively simple, the cost is low, and obvious economic benefits and environment-protection benefits are realized. The defects, in the prior art, that coupling reaction between aromatic amine and aromatic halides can be carried out at high temperature, with existence of inorganic base and under anhydrous anaerobic inert atmosphere usually, the reaction time is long, side reaction is multiple and the yield is low are overcome.

Methods and compositions are disclosed for quantifying and/or identifying a nitroderivative compound, or a residue thereof, and are applicable for assessing in vivo nitrative stress and for aiding in diagnosis of mammalian pathologies such as asthma, atherosclerosis, Alzheimer's disease, inflammation, ischemia, Parkinson's disease, and cancer. A preferred method comprises a) providing a sample containing the nitroderivative compound, or residue thereof, in the form of a diazo compound or residue thereof; b) azo-coupling the diazo compound, or residue thereof, to a target compound capable of producing a signal, to yield an azo-coupled compound; c) isolating the nitroderivative compound, or residue thereof, or the azo-coupled compound; d) quantitating and/or detecting the signal, to yield a quantitation and/or detection result; and e) determining from the quantitation and/or detection result the identity and/or concentration of the nitroderivative compound, or residue thereof, in the sample.

The invention belongs to the technical field of organic chemical synthesis, and relates to a synthetic method of triphenylene, in particular to a synthetic method of 2,7-dibromo-benzo[9,10]phenanthrene. The synthetic method includes dissolving 4,4'-dibromobiphenyl in dichloromethane; adopting a mixed solution of nitric acid and sulfuric acid for nitration reaction, and carrying out washing, concentrating and recrystallizing to obtain 2-nitro-4,4'-dibromobiphenyl, wherein the yield is 82%; reducing a nitro group into an amino group by a Fe/NH4Cl system, and subjecting the obtained product and benzene to diazo coupling reaction to obtain 4,4'-dibromo-1,1',2',1-terphenyl; performing oxidative coupling by a Pd/trifluoromethanesulfonic acid system to obtain the 2,7-dibromo-benzo[9,10]phenanthrene, wherein the yield is 62.5%, and the HPCL purity is 99.5%. The synthetic method avoids the problems of complex synthesis, low yield and environmental pollution in conventional methods.