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21 results about "Body surface area" patented technology

In physiology and medicine, the body surface area (BSA) is the measured or calculated surface area of a human body. For many clinical purposes BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass. Nevertheless, there have been several important critiques of the use of BSA in determining the dosage of medications with a narrow therapeutic index, such as chemotherapy.

Use of tapinarof for the treatment of atopic dermatitis

Topical compositions and methods for using topical compositions comprising tapinarof to treat mild to moderate atopic dermatitis or plaque psoriasis are described herein. Also described are clinical endpoints for treatment of subjects diagnosed with mild to moderate atopic dermatitis, wherein about 5% to about 35% of body surface area was affected, and Investigator Global Assessment (IGA) score was greater than or equal to 3. Also described are clinical endpoints for treatment of subjects diagnosed with chronic mild to moderate plaque psoriasis for greater than or equal to 6 months, wherein about 3% to about 20% of body surface area was affected, and Physician Global Assessment (PGA) score was greater than or equal to 2.
Owner:DERMAVANT SCI GMBH

A method for detecting a substance toxicity threshold based on a rat drinking water experiment

PendingCN122163840AIn-vivo testing preparationsToxicantDose conversion
This invention discloses a method for detecting the toxicity threshold of a substance based on a rat drinking experiment. The method of this invention includes the following steps: First, a drinking preference experiment is conducted, and then the toxicity threshold is determined: the amount of substance water and pure water consumed in the drinking preference is compared to determine the time when the rat begins to significantly avoid substance water, the mass of the toxic substance in the rat's body at that time is calculated, and the toxicity threshold of the rat is calculated; (3) dose conversion from rat to human: based on the interspecies dose conversion of body surface area, the toxicity threshold of the rat is first converted into the equivalent dose for humans to obtain the acute exposure dose, and then the acute exposure dose is converted into the chronic exposure dose for humans to obtain the substance toxicity threshold. This invention can accurately determine the toxicity threshold: it achieves toxicity assessment of low-dose exposure through spontaneous recognition behavior; it is easy to operate; and it is applicable to the toxicity assessment and non-destructive threshold determination of various substances such as environmental pollutants, chemical substances, and drugs.
Owner:PEKING UNIV

Air conditioner and control method thereof

The invention relates to an air conditioner and a control method thereof. The air conditioner comprises an indoor unit and an outdoor unit. The first sensing sensor is used for collecting environment data of a target environment; the second perception sensor is used for identifying the target state of the target object; the first temperature sensor is used for collecting the environment temperature of the target environment; the controller is used for extracting a body surface area and a bedding coverage area from the environmental data under the condition that the sleep guarding mode is started and the target object is in a sleep state; taking the area proportion of the bedding coverage area in the body surface area as the bedding coverage rate; according to the bedding coverage rate, determining a cold catching risk grade of the target object; according to the cold catching risk grade, the target age group of the target object and the working state of the indoor unit, the target temperature and the target air speed type of the air conditioner are determined; and the indoor unit and the outdoor unit are controlled, and the environment temperature is adjusted to the target temperature according to the target air speed type. By means of the air conditioner, the risk of catching cold can be lowered in a targeted mode.
Owner:HISENSE (SHANDONG) AIR CONDITIONING CO LTD

Method of treatment of soft tissue sarcoma with a peptide comprising a PCNA interacting motif

The present invention relates to pharmaceutical compositions and methods for the treatment of carcinomas and sarcomas. In particular, the invention provides a pharmaceutical composition comprising a peptide or pharmaceutically acceptable salt thereof for use in treating a carcinoma or a sarcoma in a human subject, wherein the peptide comprises an amino acid sequence as set forth in SEQ ID NO: 1 and a cell penetrating peptide and wherein the pharmaceutical composition is systemically administered to the subject weekly to provide a dose of the peptide of about 15-65 mg / m2 body surface area (BSA) per week, calculated as the free form of the peptide.
Owner:APIM THERAPEUTICS

Apparatus for measuring index of endothelial function of arterial vessel

To provide an endothelial function index value measuring device of an arterial blood vessel capable of quickly acquiring an endothelial function index value capable of evaluating an endothelial function.SOLUTION: A cross-sectional image is generated from reflected ultrasonic signals obtained by the ultrasonic probe 24 on the skin 18, the biceps muscle cross-sectional area MCSA is calculated from the muscle image area GKN of the biceps muscle in the cross-sectional image, the biceps muscle mass MCSAI (= MCSA / BSA) is calculated from the biceps muscle cross-sectional area MCSA and the body surface area BSA, and the endothelial mass index MHI (= MCSAI / MB) is calculated from the biceps muscle mass MCSAI and the muscle brightness MB of the muscle image area GKN.SELECTED DRAWING: Figure 1
Owner:UNAX CORP

Use of tapinarof for the treatment of atopic dermatitis

PendingUS20260248743A1Atopic dermatitisBiology
Topical compositions and methods for using topical compositions comprising tapinarof to treat mild to moderate atopic dermatitis or plaque psoriasis are described herein. Also described are clinical endpoints for treatment of subjects diagnosed with mild to moderate atopic dermatitis, wherein about 5% to about 35% of body surface area was affected, and Investigator Global Assessment (IGA) score was greater than or equal to 3. Also described are clinical endpoints for treatment of subjects diagnosed with chronic mild to moderate plaque psoriasis for greater than or equal to 6 months, wherein about 3% to about 20% of body surface area was affected, and Physician Global Assessment (PGA) score was greater than or equal to 2.
Owner:DERMAVANT SCI GMBH

Body Surface Area Recording Board

ActiveCN310090196SOncologyChemo therapy
1. Name of the product in this design: Body Surface Area Recording Board. 2. Purpose of this design: For use as a body surface area recording board for chemotherapy in cancer patients. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.
Owner:HUANGGANG CENT HOSPITAL

Natural polymer bioelastomer tissue compensator for tumor radiotherapy as well as preparation method and application of natural polymer bioelastomer tissue compensator

The invention relates to a natural polymer bioelastomer tissue compensator for tumor radiotherapy and a preparation method and application thereof, and the tissue compensator is composed of natural polymer and plasticizer and can be applied to tumor radiotherapy. Compared with the prior art, the tissue compensator has the advantages that by adopting the natural polymer bioelastomer material, the adaptability, dosage accuracy, clinical operation convenience, cost effectiveness and the like of an irregular body surface area are obviously superior to those of an existing tissue compensator; the tissue compensator has the advantages that the tissue compensator has excellent morphological adaptability and good biocompatibility and degradability, and is combined with a personalized preparation process, so that the dosage uniformity and the treatment effect of radiotherapy are improved, and the medical cost and the environmental burden are reduced.
Owner:BEIJING UNIV OF CHEM TECH

Doxorubicin pharmacodynamics monitoring and toxicity early warning system based on optical sensing signal

The invention relates to the technical field of biomedical engineering and medical monitoring, and discloses a doxorubicin pharmacodynamics monitoring and toxicity early warning system based on optical sensing signals. Comprising a detection presetting module used for stably depositing a human serum albumin receptor system on a detection medium through an electrochemical method to realize presetting of a peripheral subcutaneous mesenchymal baseline environment and a detection limit; the range determination module is used for determining the main field intensity range of a fluorescence signal excited by the adriamycin by using an excitation LED with the wavelength of 350-400 nm and a cut-off light filtering device; the variation acquisition module is used for acquiring the variability of the finger tip blood oxygen data and the wearable electrocardiogram data; and the reference generation module is used for determining a target of single administration dosage according to the body surface area or body weight, monitoring the level of subcutaneous interstitial residual free adriamycin after multiple times of administration, and generating reference information of skin accumulated toxicity.
Owner:BOCE BIOMEDICAL (TIANJIN) CO LTD

Body surface area chart and method

A burn assessment chart, method of generation, and system is provided. The chart includes a front profile and a rear profile corresponding to front and rear human profiles, including a head, two arms and two legs. The chart includes longitudinal lines and lateral lines that intersect within either the front or rear profile to form segments that correspond to a percentage of a human's surface area (e.g., 1%, 0.5%, etc.). The segments can be marked at locations that correspond to burn indicators on a patient, and the marked segments counted to easily determine a total percentage of surface area of a human that is burned.
Owner:RES INST AT NATIONWIDE CHILDRENS HOSPITAL

Stepped pressurization mode capable of being used for medical hyperbaric oxygen chamber

The invention relates to the technical field of medical hyperbaric oxygen chamber control, in particular to a stepped pressurization mode for a medical hyperbaric oxygen chamber, which comprises the following steps of: acquiring a heart rate variability basic value, a respiratory rate baseline value and individual physiological characteristic parameters of body surface area of a user, analyzing preset target treatment pressure, and determining the target treatment pressure; and generating a staged pressurization rate set containing the multi-stage pressure increasing rate and the corresponding target pressure sub-value through a preset stepped pressurization strategy model. After pressurization is started, the real-time heart rate variability and respiratory rate of a user are collected in real time, the pressurization rate of the current stage is adjusted according to dynamic physiological data in each pressure increasing stage, and after the pressure in the cabin reaches a target pressure sub-value, the next stage is started until the target treatment pressure is reached. According to the mode, stage pressurization parameters are customized by combining individual physiological characteristics, and the pressurization rate is dynamically regulated and controlled by real-time physiological data to adapt to the physiological state of a user.
Owner:深圳微子医疗有限公司

A three-dimensional mannequin of a body surface area innervated by a spinal nerve

ActiveCN224682741UHuman anatomyHuman body
The utility model provides a kind of three-dimensional human body model of spinal nerve innervation body surface area, specifically related to human anatomy and neurology research technical field.Aiming at two-dimensional display mode and light interference and other problems, the utility model provides a kind of three-dimensional human body model of spinal nerve innervation body surface area, including three-dimensional human body model ontology, three-dimensional human body model ontology is divided into multiple spinal nerve innervation areas, adjacent spinal nerve innervation area is separated by light-tight partition, and each spinal nerve innervation area is provided with luminous body at its sensory key point.The device enables learners to more intuitively understand and remember the distribution and function of spinal nerves.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU UNIV OF CHINESE MEDICINE

Radiotherapy body position adjusting method, device and system based on millimeter wave radar

The invention relates to the technical field of medical treatment, and discloses a radiotherapy body position adjusting method, device and system based on millimeter wave radar, and the method comprises the steps: obtaining target millimeter wave echo data of a body surface region covered by a fixed film in a state that the body surface of a patient is covered by the fixed film; according to the target millimeter wave echo data, an actual three-dimensional model reflecting the actual body position of the patient is generated; a reference three-dimensional model of the standard body position of the patient is obtained; the actual three-dimensional model and the reference three-dimensional model are registered, and the pose deviation and the positioning confidence coefficient of the current body position of the patient relative to the standard body position are determined; and according to the pose deviation and the positioning confidence coefficient, generating a body position adjustment guide instruction or prompt information of the patient. According to the technical scheme, the problem that in the prior art, the patient body position adjusting efficiency is low is solved, and the patient body position adjusting efficiency is improved.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI

Intraoperative patient body temperature distribution monitoring method and system based on infrared image

The invention relates to the technical field of medical infrared image processing and intraoperative body temperature monitoring, and discloses an intraoperative patient body temperature distribution monitoring method and system based on an infrared image. The method comprises the steps of infrared thermal imaging image acquisition and temperature calibration preprocessing, human body exposed body surface area intelligent segmentation and interference heat source elimination, anatomical area temperature field characteristic parameter extraction and analysis and intraoperative low body temperature risk dynamic evaluation and early warning. The limitation of traditional single-point temperature measurement is overcome, and adaptive monitoring parameter adjustment is realized based on a closed-loop feedback mechanism.
Owner:THE FIRST AFFILIATED HOSPITAL OF XINXIANG MEDICAL UNIVERSITY

Fat melting method and system for controlling laser intensity based on skin color and storage medium

The invention discloses a fat melting method and system for controlling laser intensity based on skin color, and a storage medium. The fat melting method comprises the following steps: constructing a three-dimensional surface model of a body surface area; acquiring skin color feature data of the region to be subjected to fat melting through a multi-mode sensor; the skin color feature data and the three-dimensional surface model are input into a pre-trained skin color grading model, the skin color grading model carries out skin color grade classification on the skin area according to the skin color feature data, and a skin color grading three-dimensional model at least comprising three skin color grades is obtained, the three skin color grades at least comprise a light skin color, a normal skin color and a deep skin color; generating a laser intensity control scheme according to the skin color grading three-dimensional model; and according to the laser intensity control scheme, grease melting laser is used for executing irradiation operation.
Owner:SHENZHEN QIAOFU INTELLIGENT EQUIPMENT CO LTD

Method of treatment of soft tissue sarcoma with a peptide comrpising a PCNA interacting motif

The present invention relates to pharmaceutical compositions and methods for the treatment of carcinomas and sarcomas. In particular, the invention provides a pharmaceutical composition comprising a peptide or pharmaceutically acceptable salt thereof for use in treating a carcinoma or a sarcoma in a human subject, wherein the peptide comprises an amino acid sequence as set forth in SEQ ID NO: 1 and a cell penetrating peptide and wherein the pharmaceutical composition is systemically administered to the subject weekly to provide a dose of the peptide of about 15-65 mg / m2 body surface area (BSA) per week, calculated as the free form of the peptide.
Owner:APIM THERAPEUTICS

Acupuncture point thermal imaging auxiliary positioning method and system for weight loss of traditional Chinese medicine

The invention provides an acupuncture point thermal imaging auxiliary positioning method and system oriented to traditional Chinese medicine weight loss, belongs to the technical field of data processing, and aims to solve the problem of poor accuracy of current acupuncture point positioning, and can utilize a baseline period infrared thermal imaging sequence and a baseline period blood perfusion sequence of a target user in a target body surface area to position acupuncture points. The target acupoint target of the target body surface area can be determined through the metabolism-perfusion divergence index distribution of the target user in combination with the dynamic response characteristics of the dynamic interested body surface area obtained through the thermal stimulation test, and the accuracy of acupuncture acupoint positioning can be improved to a certain extent in combination with the body surface function state of the target user.
Owner:BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV

An intelligent acupoint positioning method and system based on multi-modal imaging

The application relates to the technical field of medical positioning, and discloses an acupoint intelligent positioning method and system based on multi-modal imaging. The method comprises the following steps: decoupling infrared thermal imaging data and ultrasonic elastic imaging data of a target patient to obtain a feature waveform set; matching the feature waveform set with an acupoint initial position marker point set corresponding to a preset acupoint waveform template library; projecting the acupoint initial position marker point set to a body surface area corresponding to the target patient, and correcting distortion of acupoint projection to obtain a high-precision acupoint coordinate set; mapping the high-precision acupoint coordinate set to a three-dimensional space to obtain a three-dimensional acupoint model; performing real-time parameter registration on the three-dimensional acupoint model based on a real-time physiological state of the target patient to obtain a standard space parameter set of the three-dimensional acupoint model; and superimposing the standard space parameter set on the three-dimensional acupoint model to obtain a visual acupoint view. The application can improve the accuracy of acupoint intelligent positioning based on multi-modal imaging.
Owner:CHANGCHUN UNIV OF CHINESE MEDICINE

A health analysis method and device

This disclosure provides a health analysis method and apparatus, relating to computer technology and intelligent agents, particularly to the field of AI-driven healthcare. The specific implementation involves: acquiring images of body surface areas and health description text; extracting multiple region features from the body surface area images using a first feature extraction model; extracting textual features from the health description text using a second feature extraction model; performing cross-attention processing on the multiple region features and textual features to obtain fused features; and using an image understanding model, determining the health analysis result based on the fused features. This approach improves the accuracy and reliability of the health analysis results.
Owner:BEIJING BAIDU NETCOM SCI & TECH CO LTD

Blood pump for pediatric patients

Various apparatus, systems, and methods are disclosed. The method may include determining a body surface area of a patient (which may have a body surface area of about 0.6 m2 to about 1.3 m2), selecting a blood pump from a plurality of blood pumps of different sizes based on the body surface area of the patient, implanting the blood pump, and activating the blood pump to provide support to the patient. A selected blood pump may have a cannula connecting an inlet and an outlet. The sleeve may have a bend and a sleeve length that measures an axial length between the inlet and the outlet. If the body surface area is less than 0.9 m2, the cannula length may be between about 30 mm and about 46 mm.
Owner:ABIOMED INC

Patient medicine information processing method and system for thoracic surgery department

The invention discloses a medicine information processing method and system for a thoracic surgery patient, and relates to the technical field of medical information processing, and the method comprises the steps: collecting prescription medicine information and real-time physiological monitoring data of the patient; the method comprises the following steps: carrying out structured modeling on prescription drugs, and extracting metabolic enzyme categories, pharmacological targets and pharmacokinetic characteristics; sequentially analyzing the comprehensive similarity degree of adjacent drugs in the prescription to identify potential interaction risks; establishing a dynamic risk correction model by combining indexes such as heart rate, blood pressure and oxyhemoglobin saturation of the patient; in the drug risk recursion process, the risk threshold value is adjusted in real time according to the patient state, and the overall risk level of the prescription is output; individualized dose suggestions and blood concentration prediction results are generated according to parameters such as body surface area and liver and kidney functions, the system is composed of a data acquisition module, a drug modeling module, a similarity analysis module, a risk assessment module, a dose adjustment module and a visualization module, and the system is automatically operated when a doctor makes a prescription, prompts drug risks in real time and provides medication optimization suggestions.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY