17 results about "Pituitary part" patented technology

The present invention discloses a posterior pituitary pulverizing mechanism for preparing posterior pituitary injection, which relates to the field of medicine, and includes: a shell, a pulverizing mechanism is arranged in the shell, and the pulverizing mechanism includes a first motor and two rotating shafts; a feed port is arranged at the top of the shell, and a discharge port is arranged at the bottom, the rotating shaft is movably connected to the inside of the shell, and pulverizing rods are arranged on the two rotating shafts, and the pulverizing rods of the two rotating shafts cross-pulverize the posterior pituitary, the first motor is connected to one side of the shell, and the first motor drives the rotating shaft to rotate, and the posterior pituitary pulverizing and drying integrated equipment also includes a constant temperature drying mechanism. The present invention cross-extrudes and pulverizes the posterior pituitary through the pulverizing mechanism in the shell, and the raw materials remaining on the pulverizing rod after pulverization are cleaned on the metal rod wall on the other side of the rotating shaft, which can effectively clean the pulverized blocks attached to the pulverizing rod, and one side is cleaned and the other side is pulverized at the same time, which is highly efficient.

A kit and sterile preparation of purified corticotropin and methods relating thereto in which the preparation includes corticotropin extracted from a whole porcine pituitary gland including both anterior and posterior portions, and having proteins or peptides having a molecular weight higher than 4.6 kDa removed. Methods of manufacturing, testing, increasing stability, storage, and use of the purified corticotropin are also provided.

The invention relates to a multi-mode eye-brain collaborative maintenance intelligent device, and belongs to the technical field of eye-brain nursing equipment.The device is provided with an impression stimulation module, the impression stimulation module stimulates mild energy of an impression acupoint, the mild energy can be directly conducted to a paranasal sinus olfactory bulb in the deep part of a nasal cavity, the area is the starting end of paranasal sinus nerves, the paranasal sinus nerves are branches of cranial nerves, and therefore the paranasal sinus acupoint can be stimulated; the neural pathway directly extends to brain hippocampus, brain marginal tissue, pituitary gland and other core structures related to neuronutrition and brain metabolism; after stimulation, the paranasal sinus olfactory bulb and paranasal sinus nerves are activated to form a neural pathway for targeted delivery of the atomized liquid, so that the atomized particles of the brain care liquid are adsorbed on the surface of the paranasal sinus olfactory bulb and permeate into the brain along the activated neural pathway, and meanwhile, the permeability of the blood brain barrier is improved, so that the delivery resistance of the atomized liquid to related functional areas of the brain is further reduced, and the targeted delivery of the atomized liquid is realized. Precise nutrition for cranial nerves is achieved, and the problem that brain maintenance is invalid due to the fact that conventional nasal cavity atomized liquid enters the lung is thoroughly solved.

Provided are drug-device combinations and methods used for direct delivery of therapeutic drugs to the pituitary gland, wherein the drug-device combination also acts as a barrier between a sella turcica (pituitary fossa) and a sphenoid sinus to effectively trap or confine the drug substance within the sella turcica to prevent its premature escape away into the CSF from the target pituitary; thereby reducing or eliminating systemic toxicity of the drug substance. The drug-device combination includes a cap, a stem, a drug that is therapeutically effective for a pituitary gland disorder.

A method and apparatus for manipulating a temperature set-point of a human or homeothermic-animal for increasing or decreasing the body temperature above or below the prevailing body temperature for therapeutic purposes. The method includes the steps of warming or cooling sphenoid sinuses externally resulting in manipulation of the temperature of the pituitary gland which in turn results in manipulation of the body-temperature set-point and the body temperature manipulates accordingly to the new temperature set-point. A heat exchange medium can be used to warm or cool sphenoid sinuses and thus the pituitary gland. The heat exchange fluid can be liquid, or gas maintained at a predetermined temperature. Alternatively, a temperature-controlled probe can be used that upon contact with the sphenoid sinuses provides for the heat exchange.

The present invention relates to the technical field of medical devices, and particularly relates to a portable head-mounted pituitary gland stimulation device, which includes an elastic band, a mounting disc, and a cooling member. During the process of the spiral wire generating a magnetic field, heat will be generated. According to the position setting of the turbulence tube in the cooling member, when the turbulence fan blades rotate, the gas in the turbulence tube forms an air flow along the axis of the turbulence tube. After the gas in the turbulence tube flows, a pressure difference is formed inside and outside the turbulence tube, so that the gas exchanges on both sides of the turbulence tube through a plurality of circulation ports. When the gas flows through the spiral wire, the gas absorbs the heat generated when the spiral wire works. During the gas circulation process, the heat of the spiral wire is evenly distributed throughout the installation cavity, and the heat in the installation cavity is dissipated outward through the side walls of the installation box, thereby reducing the temperature when the spiral wire works.

The invention relates to a method for collecting animal hypothalamus and / or pituitary, which comprises the following steps of: (1) taking a slaughtered animal head, longitudinally cutting to the occipital condyle along the median line behind the cranium, transversely cutting at the occipital condyle to expose an occipital bone macropore, transversely cutting at the connecting line of two ears of the cranium behind the brain to the rear of two lateral ears, horizontally cutting at the rear lower parts of the two lateral ears to the occipital bone macropore, and opening a rear cranial cavity; (2) taking the hypothalamus and / or pituitary according to the following mode: taking out the complete brain from the posterior opening of the cranium in the step (1), enabling the hypothalamus to be positioned at the triangular area behind the optic nerve intersection at the bottom of the brain, and cutting and separating inwards to obtain the hypothalamus; and taking out the tissue in the pituitary fossa below the hypothalamus at the bottom of the cranial cavity, and separating to obtain the pituitary. According to the method disclosed by the invention, the complete brain tissue of the animal can be quickly obtained in a labor-saving manner by using fewer tools, an operator can accurately find the hypothalamus and the pituitary, the accuracy is high, and the damage to a sample is small.

A kit and sterile preparation of purified corticotropin and methods relating thereto in which the preparation includes corticotropin extracted from a whole porcine pituitary gland including both anterior and posterior portions, and having proteins or peptides having a molecular weight higher than 4.6 kDa removed. Methods of manufacturing, testing, increasing stability, storage, and use of the purified corticotropin are also provided.

The invention relates to the technical field of microorganisms, in particular to a probiotic composition for relieving anxiety and application, and the probiotic composition comprises lactobacillus rhamnosus LGD-0817, lactobacillus rhamnosus LDL-1708, lactobacillus plantarum LEP-1208 and lactobacillus plantarum MCA-3066. The probiotic composition is used for fermenting the traditional Chinese medicine composition, the obtained traditional Chinese medicine fermentation composition contains probiotics and traditional Chinese medicine fermentation liquor, the probiotics and the traditional Chinese medicine fermentation liquor can effectively achieve a synergistic effect, and the medicine effect of improving and treating depression is achieved; the traditional Chinese medicine fermentation composition plays a role through a plurality of ways, on one hand, the CRF content of hypothalamus and the ACTH content secreted by pituitary are reduced, so that the level of serum corticosterone is regulated and controlled, and the anti-depression and anti-anxiety effects are achieved; on the other hand, the 5-HT level of the central nervous system can be increased, the anti-depression effect is achieved, and it is prompted that the compound has the prospect of developing new anti-depression and anti-anxiety drugs and has clinical practical value.

A method and apparatus for manipulating a temperature set-point of a human or homeothermic-animal for increasing or decreasing the body temperature above or below the prevailing body temperature for therapeutic purposes. The method includes the steps of warming or cooling sphenoid sinuses remotely resulting in manipulation of the temperature of the pituitary gland without manipulation of the hypothalamus temperature which in turn results in manipulation of the body-temperature set-point and the body temperature manipulates accordingly to the new temperature set-point. A heat exchange medium can be used to warm or cool sphenoid sinuses and thus the pituitary gland. The heat exchange fluid can be liquid, or gas maintained at a predetermined temperature. Alternatively, a temperature-controlled probe can be used that upon contact with the sphenoid sinuses provides for the heat exchange.

The present invention relates to a system for use in the treatment or prevention of disease or symptoms thereof, the system comprising: at least one object, wherein the object is configured for being positioned in or adjacent to the pituitary gland or the pituitary stalk of a subject; and a device configured to generate at least one intermittent stimulating signal in the object, wherein the signal subsequently activates a release of biologically active agents.

The present invention discloses an inspection robot with adjustable internal size of a cable pipeline, the structure of which comprises a main control machine, an adjusting support rod, a top frame, side rods and moving wheels, the side rods being installed on the left and right sides of the main control machine, the adjusting support rods being fixed to the upper surface of the main control machine, the adjusting support rods being supported between the top frame and the main control machine, the side rods comprising support rods, a connecting core, a through port, a light bar, a pituitary body, auxiliary wheels, a push wheel and a protective layer, the support rods being fitted between the two pituitary bodies, the connecting core and the pituitary body being an integrated structure, the through port running through the inside of the pituitary body, the size of the main control machine itself being relatively small, and the robot can be flexibly adjusted and changed mainly by adjusting the support rods and the side rods according to the thickness of different cables, the side rods form an inverted C-shaped structure with the main control machine through their own vertical gravity, so that when the main control machine moves on the surface of the cable, the two sides are bent and wrapped by the pituitary bodies to change together with the bending shape of the cable, and the auxiliary wheels assist the side rods to move smoothly as a whole following the main control machine.

Provided are drug-device combinations and methods used for direct delivery of therapeutic drugs to the pituitary gland, wherein the drug-device combination also acts as a barrier between a sella turcica (pituitary fossa) and a sphenoid sinus to effectively trap or confine the drug substance within the sella turcica to prevent its premature escape away into the CSF from the target pituitary; thereby reducing or eliminating systemic toxicity of the drug substance. The drug-device combination includes a cap, a stem, a drug that is therapeutically effective for a pituitary gland disorder.

The invention relates to the technical field of biological tissue staining, in particular to a staining method and a staining reagent for staining a pituitary gland of a rat, and the staining method adopts a multi-dye synergistic combination of PAS staining, hematoxylin staining, fast green staining and orange G staining to stain a pituitary gland tissue section of the rat. According to the dyeing method disclosed by the invention, the rat pituitary tissue section is dyed through the synergistic combination of multiple dyes, and the core defects of fuzzy details, unclear boundary of suspected cells, light dyeing and low identification degree of traditional dyeing particles are radically solved through the precise synergy and functional complementation of the dyes.

The present invention provides a transnasal soft endoscopic minimally invasive surgical instrument for pituitary tumors, which relates to the field of medical device technology, including a catheter, an endoscope, an electrocoagulation bipolar stripping blade, an adsorbable irrigation tube, a preliminary fixing mechanism and a blocking hemostasis mechanism; the endoscope angle of the endoscope is adjustable and is used to eliminate blind spots under the microscope, the electrocoagulation bipolar stripping blade can both strip the pituitary gland and electrocoagulate the bleeding site of the wound, making tumor resection more thorough, and is particularly suitable for tumors with suprasellar extension and cavernous sinus invasion; the adsorbable irrigation tube is used for flushing the inside of the channel, and can also strip the pituitary gland by adsorption; the preliminary fixing mechanism is used to fix the catheter and further release the hemostatic agent through the blocking hemostasis mechanism to ensure complete hemostasis of the postoperative bleeding wound. The present invention can be used for high-risk pituitary tumor surgery, and can achieve smaller sellar floor fenestration, multi-segment fixation and local hemostasis, which can significantly improve the treatment effect and reduce surgical trauma.

The invention provides a transnasal soft endoscope pituitary tumor minimally invasive surgical instrument, which relates to the technical field of medical instruments, and comprises a catheter, an endoscope, an electrocoagulation bipolar stripping cutter head, an adsorbable flushing tube, a preliminary fixing mechanism and a plugging hemostasis mechanism, the endoscope angle of the endoscope is adjustable, the endoscope is used for eliminating a blind area under a microscope, the electrocoagulation bipolar stripping tool bit can strip a pituitary body and also can electrocoagulate a bleeding part of a wound surface, so that tumor excision is more thorough, and the electrocoagulation bipolar stripping tool bit is particularly suitable for tumors expanded on a saddle and invaded by sponge sinus; the adsorbable flushing pipe is used for flushing the interior of the hole channel, and meanwhile the pituitary body can be stripped through an adsorption means; the preliminary fixing mechanism is used for fixing the catheter and further releasing hemostatic through the blocking hemostasis mechanism, and it is ensured that bleeding wounds after operation are completely stopped. The device can be used for a high-risk pituitary tumor operation, smaller saddle bottom windowing, multi-section fixing and local hemostasis can be achieved, the treatment effect can be remarkably improved, and operation wounds can be reduced.

The present invention relates to a system and method, in which a distal end of an electrode is implanted in an organ, such as a pituitary gland, for intermittent electrical stimulation thereof and a proximal end of the electrode is provided with a connection plug, a distal end of which can be attached to a bone adjacent the organ, such an anterior wall of the sphenoid sinus / vomer, and a proximal end of which can be reversibly connected electrically to a wire that is connected electrically to a source of electrical stimulation for the organ.