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46results about "Corticotropin releasing factor" patented technology

CRF2 receptor agonists and their therapeutic use

The present invention provides a CRF2 agonist having desirable efficacy, pharmacokinetic properties (e.g., improved half-life), and / or physicochemical properties (e.g., improved stability and / or solubility). [Solution] Provided are compounds that are agonists of corticotropin-releasing factor receptor 2 (CRF2), which are peptides containing a specific amino acid sequence, or pharmaceutically acceptable salts thereof, and the use thereof in the treatment, particularly in the treatment or prevention of cardiovascular disease, obesity and diabetes.
Owner:SANOFI SA(FR)