The invention discloses a reinforced compound sheathing canal, a preparation method and application thereof. The reinforced compound sheathing canal sequentially comprises an inner layer, a reinforced layer and an outer layer from interior to exterior, wherein the reinforced layer comprises axial reinforcing elements and a spiral reinforcing element, the spiral reinforcing element is a single spiral element or is formed by combining two or more spiral elements, the axial reinforcing elements are disposed on the inner side or outer side of the spiral element, or are inserted between the spiral elements, and various axial reinforcing elements are uniformly arranged in the circumference direction of the sheathing canal. The reinforced compound sheathing canal provided by the invention has the advantages of thin wall, high axial strength, high radial strength, high torque transitivity and the like, can be applied to a transport system for transporting medical device implants needed in a minimally invasive treatment and can reduce the outer diameter of the transport system, so that the medical device implants are easy to arrive at lesion positions, damage to the blood vessel of a patient is reduced, and sufficient technical support is provided for reliable, successful and safe transport and implantation of the medical device implants by the transport system.