An angiocardiography pressing device comprises a base plate device, a supporting plate, an adjusting device, a support device, a positioning device, a pressing device, a driving device, a holding device and a friction device, wherein the base plate device comprises a base plate, a first supporting block, a first roller, a first bent rod, a first supporting rod, a first positioning rod, a first cross plate and a first positioning block, a second bent rod, a first spring, a first elastic rod, a second positioning block and a first support are arranged on the supporting plate, the adjusting device comprises a first rotary rod, a third positioning block, a first positioning frame, a first gear, a first rotary shaft, a second support, a second gear, a second rotary shaft, a first rotary part and a second positioning rod, the support device comprises a second supporting rod, a second cross plate, a first holding ring, a third support, a first holding rod, a first cross rod and a second holding ring, and the positioning device comprises a first cushion block, a third positioning rod, a second cross rod, a second supporting block and a fourth support.The device has a remarkable hemostatic effect and can improve hemostasis efficiency.