The invention relates to an LED lamp tube convenient to replace and install. The LED lamp tube comprises a lamp shell, a base plate, two connecting blocks and at least two lighting mechanisms. A sealing mechanism is further included. Each lighting mechanism comprises a conductive block, a lamp bead, a conductive plate, a power supply assembly, a pressing plate, a first spring, a connecting plate and two mounting assemblies. Each mounting assembly comprises a flat plate, a sleeve, a fixing block, a mounting rod, a first through hole, a second through hole, a third through hole and a fourth through hole. The LED lamp tube convenient to replace and install has the advantages that: when the lamp beads need to be replaced, people only need to take a pull hook down from a pull ring and rotate asealing cover to open an opening and then rotate the sleeves in the mounting assemblies to install and detach the conductive blocks and the lamp beads to finish the replacement of the lamp beads. Then, the sealing cover is rotated to cover the opening, and the pull hook hooks the pull ring, so that the sealing protection of the lamp shell is realized, the disassembly, assembly and replacement of the lamp beads are more convenient and faster, and the practicability of the LED lamp tube is improved.