The invention relates to the technical field of microbial fertilizer fermentation, and provides a microbial fertilizer fermentation machine and a microbial fertilizer fermentation process, the microbial fertilizer fermentation machine is provided with a plurality of fermentation tank bodies, the placement, fermentation and discharge of microbial fertilizers in the plurality of fermentation tank bodies are not mutually influenced, the preparation efficiency of the microbial fertilizers is high, and the production cost is low. The microbial fertilizer fermentation device is simple in structure and convenient to operate, the fermentation period can be well guaranteed, control and guarantee of the fermentation quality of microbial fertilizer are achieved, meanwhile, the multiple fermentation tank bodies are switched conveniently and smoothly, practicability is good, the microbial fertilizer fermentation device comprises smashing equipment and the multiple fermentation tank bodies, screening equipment is arranged on the right side of the smashing equipment, and granulation equipment is arranged on the right side of the screening equipment; cooling equipment is arranged on the right side of the granulation equipment, the carrier frame comprises a bottom bracket, a bottom frame is rotationally connected to the bottom bracket, a driving device for driving the bottom frame is mounted on the bottom bracket, the fermentation tank bodies are all mounted on the bottom frame, a center frame is connected to the bottom bracket, and a mounting frame is connected to the top end of the center frame.