The invention discloses a sealing detection system of an intercooling front intake pipe, and a use method thereof. The sealing detection system comprises a water tank, a control cabinet arranged on one side of the water tank, a detection device arranged on an upper edge of the water tank, and a lifting device located in the water tank. Compared with the prior art, the sealing detection system disclosed by the invention has the advantages that the intercooling front intake pipe is pre-fixed by a convex block and the intercooling front intake pipe is fixed by the cooperation of a ''U''-shaped ring and a nut, so that the intercooling front intake pipe is fixed firmly, and the device is not loose; a pipe head is sealed by a sealing device, and the movement of the sealing device is limited by afastening device, thereby ensuring the strict sealing of the pipe head, and accordingly, the sealing effect is good; and a clamping portion is arranged on a vertical limiting rod of the sealing device, the clamping portion is close fit with a clearance to prevent the occurrence of a gap between a gland and the pipe head when the fastening device is screwed, thereby avoiding the influence of the poor sealing effect of the pipe head on the detection result and playing a secondary limiting role, and furthermore, the system is simple in overall structure, convenient to use, good in sealing and detection effects and suitable for promotion and application.