32results about How to "Good activity" patented technology

The invention provides a broad spectrum heavy metal activity deactivator preparation method. The present invention relates to a soil conditioning agent preparation method, which comprises the following steps: (A) taking humic acid-rich peat, digest compost or a forest soil humus layer, and carrying out screening to provide a spare use; (B) adding the humic acid-rich material to HCl or HNO3 to soak, and stirring 2-3 times; (C) filtering the soaked material with a bamboo drying pad, washing 2-3 times with clear water, and carrying out air drying to a moisture content of less than 5%; (D) sequentially adding ZnSO4.7H2O, sodium silicate and sodium selenite to the material obtained from the step (C), carrying out aging on the mixed material for 2-3 days and uniformly mixing; and (E) adding limestone powder to the material obtained from the step (D), and completely and uniformly mixing to prepare the broad spectrum heavy metal deactivator. With the combination inhibitor prepared by the preparation method, activities of soil heavy metals can be significantly inactivated, the heavy metals can be inhibited from entering the food chain, and risks on human health by the heavy metals can be reduced.

It is an object of the present invention to provide a catalyst for manufacturing a carboxylic ester, which has superior catalytic activity. The present invention relates to a catalyst for preparing a carboxylic ester, used in a) a reaction for preparing a carboxylic ester by reacting oxygen, an aldehyde, and an alcohol, or b) a reaction for manufacturing a carboxylic ester by reacting oxygen and one or more types of alcohol, comprising a carrier and 1) ultrafine gold particles and/or 2) ultrafine metal particles containing gold and a second element other than gold, having an average particle diameter of not more than 6 nm, are supported on the carrier.

The invention provides cyclic carboxamide compounds and analogues thereof of Formula I

and the pharmaceutically salts and hydrates thereof.

The variables R, R₁, R₆-R₈, R₁₆, R₁₈, R₁₉, M, n, T, Y, and Z are defined herein. Certain compounds of Formula I are useful as antiviral agents. Certain cyclic carboxamide compounds and cyclic carboxamide analogues disclosed herein are potent and/or selective inhibitors of viral replication, particularly Hepatitis C virus replication. The invention also provides pharmaceutical compositions containing one or more cyclic carboxamide compounds or cyclic carboxamide analogues and one or more pharmaceutically acceptable carriers. Such pharmaceutical compositions may contain a cyclic carboxamide compound or cyclic carboxamide analogue as the only active agent or may contain a combination of a cyclic carboxamide compound or cyclic carboxamide analogue and one or more other pharmaceutically active agents. The invention also provides methods for treating viral infections, including Hepatitis C infections.

The invention discloses a carbon-free ladle brick and a preparation method thereof. The carbon-free ladle brick is prepared by using bauxite chamotte, a corundum raw material, magnesium oxide and alumina micro powder as main raw materials, adding iron oxide, a magnesium chloride solution, sodium hexametaphosphate and canary dextrin, mixing the above-mentioned materials by using special procedures, storing an obtained mixed for 30 min, carrying out compression molding and drying the mixture at a temperature of 200 DEG C for 24 h. According to the invention, iron oxide and alumina micro powder are enabled to exist in gaps between aggregate and powder and form hercynite with a low thermal expansion coefficient at a medium-high temperature, and no excess iron oxide enters into a matrix, which enables the ladle brick to have good high temperature stability and anti-stripping performance; therefore, the problem that molten steel carburetting caused by high temperature melting loss of a refractory brick influences smelting quality is overcome, and the prepared carbon-free ladle brick has excellent performances of high strength, washing resistance, a long service life, etc.

The invention discloses a rhodium complex as well as a preparation method and application thereof. The rhodium complex is monochloride o-mono-methoxy benzaldehyde acetal 4-methyl-3-thiosemicarbazide-pentamethylcyclopetadienyl-rhodium (III), and the rhodium complex can serve as the application for preparing drugs for treating cancers. The structural formula of the rhodium complex is shown in the Specification.

The invention discloses a method for separating and purifying oligomeric proanthocyanidins. The method comprises the following steps: carrying out water precipitation filtration and microfiltration treatment of a proanthocyanidin crude extract liquid, carrying out chromatography adsorption by a specific macroporous resin, and eluting by an ethanol solution to obtain a proanthocyanidin-containing eluate; and carrying out nanofiltration membrane concentration of the eluate, and drying to obtain a product.

The invention relates to sinomenine derivatives, methods for their synthesis and their applications. The sinomenine derivatives include oxidation derivatives, and C-10 substituted sinomenine derivatives. Based on the readily oxidizable phenol group on sinomenine structure, using oxidation, oxidative dearomatization, or conjugated addition aromatization, one can introduce C-10 substitutions to synthesize the sinomenine derivatives. The sinomenine derivatives of the invention have the following structures:

Using in vitro TNF-α inhibition assay, the activities of the synthetic compounds are assessed. Results from these assays shown that most compounds have anti-inflammatory effects, and some compounds have better activities than that of sinomenine. These compounds may be used in treating immune diseases such as rheumatoid arthritis (RA).

The invention discloses an activated waste rubber powder modified asphalt material. Firstly, a hydrogen peroxide/potassium ferrate complex oxidizing system is used for performing oxidation treatment on waste rubber powder, so that a large number of active groups are exposed at the surface thereof; then, silane coupling agent hydrolysate is used for performing modification treatment on the waste rubber powder; an efficient activity effect is achieved, so that the compatibility of the obtained waste rubber powder and the substrate asphalt is better; the performance of the composite asphalt material is improved; in addition, activated palygorskite can improve the temperature resistant performance and the anti-aging performance of the composite asphalt material; waste gas in the production process can also be adsorbed; the dirt is reduced; under the crosslinking catalysis effect of benzaldehyde, the ductility of the composite material is effectively improved; the waste gas release quantity is further controlled; the prepared modified asphalt material has excellent performance and environment-friendly effect; the economic values are high.

The invention discloses a hydrocracking catalyst for distillate oil, which comprises alumina, ZSM-23 elite and Y-shape elite modified by cation exchange with VIB and VIII groups metal as carriers, and active metal constituents from VIB and VIII groups; adjusting acid distribution of Y-shape elite special the B and L acids. This invention has well open-loop, hydrogenation and isomerization activity, increase hexadecane value in maximum limit, and ensures high diesel yield.

A core-shell support, comprising:

• • a core which comprises at least one oxygen storage/release material selected from the group consisting of ceria-zirconia based solid solutions and alumina-doped ceria-zirconia based solid solutions; and
  • a shell which comprises a rare earth-zirconia based composite oxide represented by a composition formula: (Re_1-xCe_x)₂Zr₂O_7+x (where Re represents a rare earth element, and x represents a number of 0.0 to 0.8) and with which an outside of the core is coated,
  • the rare earth-zirconia based composite oxide comprising crystal particles having a pyrochlore structure, and
  • the rare earth-zirconia based composite oxide having an average crystallite diameter of 3 to 9 nm.

The invention discloses a supported nano Pd/MgO catalyst which comprises nano magnesium oxide as a carrier and palladium as an active component loaded on the carrier, wherein the content of the palladium is 3-10% of total mass of the catalyst. A preparation method of the catalyst comprises the following steps: step I: preparing a palladium-containing aqueous solution, step II: adding nano magnesium oxide into the palladium-containing aqueous solution prepared in the step I, and performing continuous stirring for 1-5h at room temperature, and step III: adding a reducer into a solution preparedin the step II for reduction treatment, reducing divalent palladium in soluble palladium salt to zero-valent palladium, performing filtration to form a filter cake and performing water washing to formthe supported nano Pd/MgO catalyst. The invention provides a method of preparing a biphenyl compound by applying the nano Pd/MgO catalyst into a Suzuki coupling reaction at the same time. The catalyst has the advantages of low possibility of losing metal Pd in the catalyst, recyclability, high catalytic reaction activity, short reaction time and the like.

The invention discloses a PCR pre-packing reagent. The PCR pre-packing reagent is a lyophilized reagent, the lyophilized reagent is composed of a PCR reaction mixed solution and a cryoprotectant, andthe weight of the cryoprotectant is 6.25-30% (w/v) of the volume of the PCR reaction mixed solution. The PCR pre-packing reagent simplifies the PCR operation step and improves the experimental efficiency; and the PCR pre-packing reagent also has a high amplification activity and a high quality stability, and can be stored at room temperature for a long term to reduce the storage and transportationcost of the reagent. The invention also provides a reaction tube pre-loaded with the PCR reagent, the reaction chamber of the reaction tube is filled with the PCR pre-packing reagent, an identification code for distinguishing different reaction tubes is arranged on the surface of the reaction tube, and the identification code does not block lights transmitting out of the reaction tube from the reaction chamber. Distinguishing of the different reaction tubes with the identification code is beneficial to achieve automatic matching of PCR detection results with sample and index information, so the automatic operation of PCR detection experiments is realized.

The invention discloses an organic metal rhodium compound and a preparation method and application thereof. The organic metal rhodium compound is chlorine-(1E,6E)-1,7-bis(3,4-dimethoxyphenyl)-4-(p-methylamino phenyl vinyl)-1,6-heptadiene-2,5-diketone-pentamethyl cyclopentadienyl rhodium (III). The organic metal rhodium compound can be applied to preparation of a drug for treating cancer and resisting bacteria. The structural formula of the organic metal rhodium compound is shown in the specification.

The invention relates to the technical field of asphalt equipment and discloses an energy-saving and environment-friendly heating and cooling integrated high-efficiency asphalt laying device. The device comprises a stirring bin, wherein a stirring rod is movably connected to the interior of the stirring bin, a heating rod is fixedly connected to the interior of the stirring bin, and a feeding portis formed in the top of the stirring bin. According to the energy-saving and environment-friendly heating and cooling integrated high-efficiency asphalt laying device, through cooperative use of thestirring rod and the pushing mechanism, when asphalt is laid, the asphalt stored in the stirring bin can be simultaneously and continuously stirred and heated, the optimal state and activity of the asphalt are kept, the laying effect is guaranteed, the working efficiency is improved, and the energy-saving and environment-friendly heating and cooling integrated high-efficiency asphalt laying deviceis suitable for popularization; the laying quality is guaranteed, and energy waste and economic losses are avoided; and through cooperative use of a fan and a second belt, when asphalt is extruded out of an extrusion opening, the fan rotates to cool the laid asphalt pavement, and the laying quality is guaranteed to the maximum extent.

A conjugate of formula (I):

Ab-(DL)_p  (I)

wherein:

• Ab is an antibody that binds to AXL;
• DL is

The invention discloses a processing method for electroplating pretreatment. The method comprises the following steps of step 1, preparing a metamorphic loading agent; step 2, pre-activating a metal piece: activating the to-be-treated metal piece at the temperature of 210-250 DEG C for 20-30 minutes, then cooling the metal piece to 150 DEG C at the speed of 2 DEG C/min, and finally quenching the metal piece to room temperature by water; and step 3, treating the metamorphic loading agent. According to the method, the metal piece is firstly activated, and the activating treatment adopts 210 DEG C high-temperature, variable-temperature and water quenching treatment, so that the surface active performance of the metal piece is improved, the porosity of the surface structure of the metal piece is improved, and the subsequent modification treatment on the metal piece by the modification loading agent is facilitated.

A saccharide derivative represented by Chemical Formula (1) or (2), or a salt thereof, includes units of a monosaccharide linked to each other in a chainlike or cyclic manner through glycosidic bonding and has antimicrobial action. In the formulae, R¹ represents an amino-containing structure; and n represents an integer of 3 or more. A saccharide derivative represented by Chemical Formula (5) or (6), or a salt thereof, includes units of a monosaccharide linked to each other in a chainlike or cyclic manner through glycosidic bonding and has antimicrobial activity enhancing action. In the formulae, R³ represents an amino-containing structure; R⁴ is selected from acetyl and propanoyl; and n represents an integer of 3 or more.

The invention relates to a method for preparing ketone compounds. A reaction is carried out at normal pressure in a two-stage fixed bed reactor, a first-stage catalyst is CeO2, a reaction temperatureis 300-450 DEG C, a raw material is acetic acid, and a feeding mass space velocity of the raw material is 0.1-1.0 h<-1>. Acetone is generated after the acetic acid is subjected to a ketonization reaction in the first stage, and then a second-stage reaction is carried out. A second-stage catalyst is CeO2-SnO2, a reaction temperature is 350-450 DEG C, a raw material is ethanol, and a feeding mass space velocity of the raw material is 0.1-1.0 h<-1>. 2-pentanone and 4-heptanone are prepared through dehydrogenation and an Aldol condensation reaction in the second stage. The method is characterizedin that CeO2 and a cerium-based composite oxide are used as catalysts, and the catalyst is simple to prepare and has good stability. The ketone compounds are generated by efficiently catalyzing aceticacid and ethanol through a two-stage method, the conversion rate is up to 35% (based on the total carbon number), and the total selectivity of the ketone compounds can reach 99%, wherein the selectivity of 2-pentanone is 85%, and the selectivity of 4-heptanone is 15%. In the process, acetic acid and ethanol are taken as raw materials, the raw material source is wide, and a potential industrial application prospect is achieved.

The invention relates to a doped carbon material, a platinum-carbon catalyst and a preparation method and application thereof. In the XPS analysis of the carbon material, a characteristic peak exists at 135.8 +/-0.5 ev. The platinum-carbon catalyst prepared from the carbon material has excellent catalytic performance and carbon corrosion resistance when being used for catalyzing oxygen reduction reaction.

The invention provides an extraction method of crocodile polypeptide, and belongs to the technical field of extraction of biological samples. The extraction method comprises the steps of performing heating for softening on crocodile tissue, then performing high-temperature constant-temperature hydrolysis, and then concentrating and drying hydrolysates to obtain crocodile polypeptide extract powder. The extraction method has the advantages of being simple to operate, high in extraction efficiency and high in extract activity.

The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, esters, or prodrugs thereof:

which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

The invention discloses a semiconductor structure and a production method thereof. The production method comprises the steps of forming a nitrogen-containing compound layer on a substrate; carrying out a heat treatment process on the nitrogen-containing compound layer; and forming a photoresist pattern layer, wherein at least one part of nitrogen-containing compound layer is exposed out of the photoresist pattern layer. According to the production method, the heat treatment process is carried out on the nitrogen-containing compound layer before the photoresist pattern layer is formed, and theactivity of a nitrogen bond on the surface of the nitrogen-containing compound layer can be destroyed by the heat treatment process, so that the nitrogen bond does not react with air or a hydrogen bond in a cleaning process on the surface of the nitrogen-containing compound layer during the formation of the photoresist pattern layer, thereby preventing generation of residual gum. Therefore, CD ofthe semiconductor structure produced through the production method is stable and the semiconductor structure has good product quality and performance.

The invention discloses a target material for semiconductor industry. The target material comprises the following raw materials in parts by weight: 10-20 parts of germanium, 5-10 parts of tellurium, 4-10 parts of selenium, 1-2 parts of a modified bentonite dispersant, 1-6 parts of a modifier, 1-3 parts of rare earth agent modified graphite powder and 30-40 parts of silicon powder. In the preparation of the target material for the semiconductor industry, the target material is prepared from germanium, tellurium, selenium and other raw materials in proportion, the added modified bentonite dispersing agent and the rare earth agent modified graphite powder are treated by a modifier and then are applied to a product as a pretreatment additive, so that the performance of the product can be remarkably improved, and the density and the shrinkage degree of the raw materials are improved.

The present invention discloses a preparation method of catalyst for preparing transition metal carbide, its precursor is formed from carbon material and transition metal compound. Said invention adopts the impregnation or mechanical mixing method to load the transmition metal on the carbon material, and the weight percentage of the transition metal compound loaded quantity is in the range of 1-200%, and the obtained sample can be heated to 500-1000 deg.C in heating rate of 1-20 deg.C/min under the atmosphere of hydrogen gas, then thermostatic reduced for 0.1-10 hr, and reduced to room temp. and passivated by using 1% of oxygen gas under the atmosphere of hydrogen gas or reduced to room temp. under the inert-atmosphere so as to obtain the correspondent transion metal carbide or transition metal carbide loaded on the carbon material.

The invention relates to a use of a compound in preparation of drugs for treatment and/or prevention of drug moderate lung cancer and/or drug-resistant lung cancer, and a composition of the compound,specifically, a use of the compound represented by a structural formula I and/or a pharmaceutically acceptable salt thereof in preparation of the drugs for treatment and/or prevention of lung cancer,wherein R1 and R6 are hydroxyl respectively, and R2, R3, R4 and R5 are selected independently from one of hydrogen, alkyl and hydroxyl; preferably, R2, R3, R4 and R5 are selected independently from hydrogen or alkyl; and more preferably, the alkyl is selected from one of methyl, ethyl and propyl.

The invention provides a plant component moistening type anti-decoloration lipstick as well as a preparation method and a use method of the plant component moistening type anti-decoloration lipstick. The plant component moistening type anti-decoloration lipstick is prepared from the following raw materials in parts by weight: 10 to 20 parts of ethylhexyl palmitate, 5 to 10 parts of polydimethylsiloxane, 1 to 6 parts of pure ozocerite, 2 to 5 parts of polydimethylsiloxane cross-linked polymer, 1 to 4 parts of modified mica, 1 to 3 parts of microcrystalline wax, 1 to 2 parts of polyethylene, 1 to 3 parts of isododecane and 1 to 2 parts of bis-PEG-15 polydimethylsiloxane/IPDI copolymer. The lipstick disclosed by the invention has the effects of moistening, decoloring prevention and cup sticking prevention, the use effect of the lipstick can be improved by proportioning and selecting the raw materials, the modified mica is added into the lipstick, the active performance of the mica is enhanced by active treatment of the mica, and then thermal contraction and cold contraction treatment is adopted, so that the shrinkage degree of the mica is improved, and the shrinkage efficiency of a mica sheet layer is improved.

The invention relates to a preparation method of a sulfur-phosphorus-doped carbon material and a product and application thereof, and the method comprises the following steps: contacting a sulfur-doped carbon material with a phosphorus source, and carrying out high-temperature treatment in inert gas to obtain the sulfur-phosphorus-doped carbon material. The platinum-carbon catalyst prepared by taking the sulfur-phosphorus doped carbon material as a carrier has excellent catalytic performance.

Provided are prodrugs of a bicyclic substituted pyrimidine type PDE-5 inhibitors, pharmaceutically acceptable salts or stereoisomers thereof. Also provided are methods for preparing these prodrug compounds, pharmaceutical preparations, and pharmaceutical compositions, as well as a use of these compounds, pharmaceutical preparations and pharmaceutical compositions in the manufacture of medicaments for treatment and/or prophylaxis of sexual dysfunction and lower urinary tract symptoms.

The invention relates to a phosphorus-boron-doped carbon material, a platinum-carbon catalyst and a preparation method and application of the phosphorus-boron-doped carbon material and the platinum-carbon catalyst, and the phosphorus-boron-doped carbon material has a characteristic peak at 190.5 +/-0.5 eV in a B1s spectrum peak of XPS analysis of the phosphorus-boron-doped carbon material. A platinum-carbon catalyst taking the phosphorus-boron doped carbon material as a carrier has good mass ratio activity, ECSA and excellent ECSA stability.