Composition containing bifidobacteria for adjusting intestinal flora and enhancing immunity

Abstract

A composition containing bifidobacteria for adjusting intestinal flora and enhancing immunity is characterized by comprising, by weight, 0.01-10% of bifidobacteria, 10-50% of oligosaccharide, 0.01-10% of vitamin, and 0.01-10% of metals, with the balance being auxiliary materials. The composition containing bifidobacteria provided by the invention has functions of adjusting intestinal flora and enhancing immunity. The composition can be made into capsules, soluble granules, granules, tablets, etc., and applied in food, health product and pharmaceutical fields.

Description

Technical field [0001] The invention relates to a bifidobacterium product, in particular to a bifidobacterium-containing composition for regulating intestinal flora and enhancing immunity, belonging to the technical field of bifidobacterium product preparation. Background technique [0002] The intestinal microecosystem is the largest and most complex microecosystem of the human body, and it is also the most important and active part of the human microecosystem. Intestinal flora is an important part of the intestinal defense barrier. A balanced intestinal flora is very important to human health. However, due to the aging of the body, environmental pollution, dietary changes, and the abuse of antibiotics, the human intestinal microecosystem is often destroyed, causing imbalance of the intestinal flora, seriously affecting the body’s immune system, resulting in weakened immune function and leading to bacteria Group translocations induce endogenous infections, cause body diseases, ...

AI Technical Summary

Problems solved by technology

Patent CN 1056877C discloses a bifidobacterium microcapsule and its manufacturing method, CN 1063051C discloses a bifidobacterium compound living bacteria preparation, and CN 1149092C discloses an acid-resistant enteric-coated microcapsule of active bifidobacterium strain , the three patents all use microencapsulation technology, which enhances the ability of bifidobacteria to resist the external environment, and can resist the erosion of gastric acid and bile salts. It can still effectively protect its activity when stored in a liquid state or at room temperature for a long time. However, Generally, it takes more than six hours for bifidobacteria embedded in microcapsules to dissolve and release after reaching the intestinal tract, and the effect is limited

Patent CN 1116410C discloses a high-viability live bacteria preparation and its preparation method. In this patent, Bifidobacteria are subjected to liquid deep-layer high-density culture, and the number of viable bacteria in the fermentation liquid is 5×10 8 cfu / mL, the bacteria adopts four protection measures of freeze-dried powder, microcapsules, nitrogen-filled canned capsules, and nitrogen-filled double-aluminum packaging to make live bacteria preparations, which significantly improves the survival rate of bacteria. However, the preparation process is cumbersome and time-consuming, and the number of viable bacteria is still low after high-density culture, and the microencapsulation technology used in the later stage also has the problem of exerting beneficial effects

Patent CN 100519738C discloses a bifidobacterium live bacteria preparation and its special protective agent, and CN 100497594C discloses a composite protective agent of high-activity bifidobacterium dry powder preparation. The two patents use a special protective agent and use it to prepare The resulting freeze-dried powder has an average live bacteria content of 1.0×10 11 More than cfu / g, while solving the problem of difficulty in storing bifidobacteria products at room temperature, but the effectiveness of bifidobacteria effectively colonizing the intestinal tract and exerting a probiotic effect has not been solved

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